WormBase Tree Display for WBProcess: WBbiopr:00000003
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WBbiopr:00000003 | Public_name | Autophagy | |||
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Summary | Autophagy is the degradation of cytoplasmic components through an autophagolysosome (autolysosome). Of the many types of autophagy in nature, macroautophagy, which involves the sequestration of cellular material by a double-membrane autophagosome, has been observed in C. elegans. The steps in this degradation process include nucleation of vesicle formation, expansion of the membrane with concomitant capture of cellular components (vesicle elongation), autophagolysosome or autolysosome, formation (autophagosome fusion with lysosome), and completion (vesicle breakdown and the lysis of the captured cytoplasmic material). | ||||
Related_topic | Specialisation_of | WBbiopr:00000052 | |||
Involved_entity | Gene | WBGene00018294 | Paper_evidence | WBPaper00006070 | |
WBGene00006786 | Paper_evidence | WBPaper00031045 | |||
WBPaper00006070 | |||||
WBGene00003954 | Paper_evidence | WBPaper00032500 | |||
WBPaper00028951 | |||||
WBGene00006921 | Paper_evidence | WBPaper00031045 | |||
WBGene00006911 | Paper_evidence | WBPaper00031045 | |||
WBGene00002980 | Paper_evidence | WBPaper00031045 | |||
WBPaper00006070 | |||||
WBPaper00041209 | |||||
WBGene00010882 | Paper_evidence | WBPaper00006070 | |||
Interaction (37) | |||||
Molecule | WBMol:00003513 | Paper_evidence | WBPaper00041209 | ||
Associated_with | Phenotype | WBPhenotype:0000736 | |||
GO_term | GO:0006914 | ||||
Reference (33) |