WormBase Tree Display for Variation: WBVar00143373
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WBVar00143373 | Name | Public_name | e652 | ||||||
---|---|---|---|---|---|---|---|---|---|
Sequence_details | Mapping_target | F47A4 | |||||||
SeqStatus | Pending_curation | ||||||||
Variation_type | Allele | ||||||||
Origin | Species | Caenorhabditis elegans | |||||||
Strain | WBStrain00004192 | ||||||||
Laboratory | CB | ||||||||
Status | Live | ||||||||
Affects | Gene | WBGene00001081 | |||||||
Interactor | WBInteraction000052284 | ||||||||
Genetics | Mapping_data | In_2_point | 624 | ||||||
3153 | |||||||||
3156 | |||||||||
In_multi_point | 531 | ||||||||
532 | |||||||||
533 | |||||||||
1195 | |||||||||
1196 | |||||||||
In_pos_neg_data | 3154 | ||||||||
Description | Phenotype | WBPhenotype:0000031 | Person_evidence | WBPerson261 | |||||
Curator_confirmed | WBPerson712 | ||||||||
Remark | slow-growing (XX) | Person_evidence | WBPerson261 | ||||||
Curator_confirmed | WBPerson712 | ||||||||
WBPhenotype:0000032 | Paper_evidence | WBPaper00001011 | |||||||
Curator_confirmed | WBPerson712 | ||||||||
Remark | XX and XO animals are sick. | Paper_evidence | WBPaper00001011 | ||||||
Curator_confirmed | WBPerson712 | ||||||||
EQ_annotations | Life_stage | WBls:0000057 | PATO:0000460 | Paper_evidence | WBPaper00001011 | ||||
Curator_confirmed | WBPerson712 | ||||||||
WBls:0000056 | PATO:0000460 | Paper_evidence | WBPaper00001011 | ||||||
Curator_confirmed | WBPerson712 | ||||||||
WBPhenotype:0000065 | Person_evidence | WBPerson261 | |||||||
Curator_confirmed | WBPerson712 | ||||||||
Remark | very abnormal small or inviable male (XO) | Person_evidence | WBPerson261 | ||||||
Curator_confirmed | WBPerson712 | ||||||||
WBPhenotype:0000314 | Person_evidence | WBPerson261 | |||||||
Curator_confirmed | WBPerson712 | ||||||||
WBPhenotype:0000409 | Person_evidence | WBPerson261 | |||||||
Curator_confirmed | WBPerson712 | ||||||||
Remark | variable, difficult to score (ES2) at all XX stages XX, easy to score (ES3) at all X0 stages | Person_evidence | WBPerson261 | ||||||
Curator_confirmed | WBPerson712 | ||||||||
Ease_of_scoring | ES2_Difficult_to_score (2) | ||||||||
WBPhenotype:0000583 | Paper_evidence | WBPaper00001011 | |||||||
Person_evidence | WBPerson261 | ||||||||
Curator_confirmed | WBPerson712 | ||||||||
Remark | XX and XO animals are strong dumpy. | Paper_evidence | WBPaper00001011 | ||||||
Curator_confirmed | WBPerson712 | ||||||||
EQ_annotations | Life_stage | WBls:0000057 | PATO:0000460 | Paper_evidence | WBPaper00001011 | ||||
Curator_confirmed | WBPerson712 | ||||||||
WBls:0000056 | PATO:0000460 | Paper_evidence | WBPaper00001011 | ||||||
Curator_confirmed | WBPerson712 | ||||||||
WBPhenotype:0001582 | Paper_evidence | WBPaper00001011 | |||||||
Person_evidence | WBPerson261 | ||||||||
Curator_confirmed | WBPerson712 | ||||||||
Remark | XX animals have slightly enhanced lin-14 mutant seam cells (41% n=20) compared to lin-14 animals alone (30% n=40). XO males have 79% (n=20) mutant seam cell nuclei, which is significantly higher than XO lin-14 animals (50% n=20) and more similar to lin-14/Df XX animals (84% n=20). | Paper_evidence | WBPaper00001011 | ||||||
Curator_confirmed | WBPerson712 | ||||||||
reduced X chromosome expression | Person_evidence | WBPerson261 | |||||||
Curator_confirmed | WBPerson712 | ||||||||
EQ_annotations | Life_stage | WBls:0000057 | PATO:0000460 | Paper_evidence | WBPaper00001011 | ||||
Curator_confirmed | WBPerson712 | ||||||||
WBls:0000056 | PATO:0000460 | Paper_evidence | WBPaper00001011 | ||||||
Curator_confirmed | WBPerson712 | ||||||||
Phenotype_assay | Temperature | 20 | Paper_evidence | WBPaper00001011 | |||||
Curator_confirmed | WBPerson712 | ||||||||
Genotype | lin-14(n179) or him-5/+; lin-14(n179)/0 | Paper_evidence | WBPaper00001011 | ||||||
Curator_confirmed | WBPerson712 | ||||||||
Phenotype_not_observed | WBPhenotype:0000064 | Paper_evidence | WBPaper00001011 | ||||||
Curator_confirmed | WBPerson712 | ||||||||
Remark | No strong bias in viability between XX (83%, n=569) and XO (78%, n=377) animals were observed. | Paper_evidence | WBPaper00001011 | ||||||
Curator_confirmed | WBPerson712 | ||||||||
Phenotype_assay | Treatment | XX viability was determined directly by counts of eggs from homozygous dpy-22 hermaphrodites and following development through adulthood. XO viability was determined by counts of progeny from dpy-22 hermaphrodites mated to WT males. | Paper_evidence | WBPaper00001011 | |||||
Curator_confirmed | WBPerson712 | ||||||||
Reference | WBPaper00001011 | ||||||||
WBPaper00016237 | |||||||||
WBPaper00016243 | |||||||||
WBPaper00016415 | |||||||||
Remark | This allele causes a frameshift after the G residue at amino acid position 2333. | Paper_evidence | WBPaper00025050 | ||||||
Method | Allele |