WormBase Tree Display for Variation: WBVar00143314
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WBVar00143314 | Evidence | Paper_evidence | WBPaper00028438 | |||||
---|---|---|---|---|---|---|---|---|
Name | Public_name | e580 | ||||||
Sequence_details | Mapping_target | K03E6 | ||||||
Type_of_mutation | Substitution | |||||||
SeqStatus | Pending_curation | |||||||
Variation_type | Allele | |||||||
Origin | Species | Caenorhabditis elegans | ||||||
Strain | WBStrain00027058 | |||||||
Laboratory | CB | |||||||
Status | Live | |||||||
Affects | Gene | WBGene00006741 | ||||||
Interactor | WBInteraction000052184 | |||||||
Genetics | Mapping_data | In_2_point | 4453 | |||||
Description | Phenotype | WBPhenotype:0001610 | Paper_evidence | WBPaper00028438 | ||||
Curator_confirmed | WBPerson2987 | |||||||
Remark | Table 1 | Paper_evidence | WBPaper00028438 | |||||
Curator_confirmed | WBPerson2987 | |||||||
Affected_by | Molecule | WBMol:00007859 | Paper_evidence | WBPaper00028438 | ||||
Curator_confirmed | WBPerson2987 | |||||||
Phenotype_not_observed | WBPhenotype:0000523 | Paper_evidence | WBPaper00028438 | |||||
Curator_confirmed | WBPerson2987 | |||||||
Remark | Table 1 | Paper_evidence | WBPaper00028438 | |||||
Curator_confirmed | WBPerson2987 | |||||||
Affected_by | Molecule | WBMol:00001705 | Paper_evidence | WBPaper00028438 | ||||
Curator_confirmed | WBPerson2987 | |||||||
WBMol:00004563 | Paper_evidence | WBPaper00028438 | ||||||
Curator_confirmed | WBPerson2987 | |||||||
WBPhenotype:0001612 | Paper_evidence | WBPaper00002358 | ||||||
Curator_confirmed | WBPerson712 | |||||||
Remark | Animals have a similar EC50 (1030 20 mM) compared to N2 (1050 25 mM). | Paper_evidence | WBPaper00002358 | |||||
Curator_confirmed | WBPerson712 | |||||||
Phenotype_assay | Treatment | 50 animals were scored for mobility for 10 sec. at each concentration of ethanol after 5 min exposure. EC50's (concentration at which 50% of the animals were immobile for >10 sec) were determined from a dose response curve over a minimum of 12 concentrations (mM). Immobility was used an as endpoint. Upon removal from ethanol, immobility was reversible within 10-15 min. Treatment and scoring of anesthetic responses are described in Sedensky and Meneely, 1987; Morgan et al. , 1990; Morgan and Sedensky, 1994. | Paper_evidence | WBPaper00002358 | ||||
Curator_confirmed | WBPerson712 | |||||||
Temperature | 22-24C | Paper_evidence | WBPaper00002358 | |||||
Curator_confirmed | WBPerson712 | |||||||
Reference | WBPaper00015366 | |||||||
WBPaper00022645 | ||||||||
WBPaper00015173 | ||||||||
WBPaper00022026 | ||||||||
WBPaper00002358 | ||||||||
WBPaper00018537 | ||||||||
WBPaper00028438 | ||||||||
WBPaper00065317 | ||||||||
Method | Substitution_allele |