WormBase Tree Display for Variation: WBVar00143038
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WBVar00143038 | Name | Public_name | e211 | |||||
---|---|---|---|---|---|---|---|---|
Sequence_details | SeqStatus | Pending_curation | ||||||
Variation_type | Allele | |||||||
Origin | Species | Caenorhabditis elegans | ||||||
Strain | WBStrain00004129 | |||||||
WBStrain00030691 | ||||||||
Laboratory | CB | |||||||
Status | Live | |||||||
Affects | Gene | WBGene00002974 | ||||||
Interactor | WBInteraction000518500 | |||||||
WBInteraction000518501 | ||||||||
WBInteraction000556207 | ||||||||
Genetics | Mapping_data | In_multi_point | 1118 | |||||
2656 | ||||||||
Description | Phenotype | WBPhenotype:0000421 | Paper_evidence | WBPaper00000484 | ||||
WBPaper00035548 | ||||||||
Curator_confirmed | WBPerson2021 | |||||||
WBPerson712 | ||||||||
Affected_by | Molecule | WBMol:00004019 | Paper_evidence | WBPaper00000484 | ||||
Curator_confirmed | WBPerson2021 | |||||||
Phenotype_assay | Treatment | 1mM levamisole | Paper_evidence | WBPaper00000484 | ||||
Curator_confirmed | WBPerson2021 | |||||||
WBPhenotype:0000643 | Paper_evidence | WBPaper00035548 | ||||||
WBPaper00041959 | ||||||||
Person_evidence | WBPerson261 | |||||||
Curator_confirmed | WBPerson712 | |||||||
WBPerson557 | ||||||||
Remark | Almost normal movement in absence of drug. | Person_evidence | WBPerson261 | |||||
Curator_confirmed | WBPerson712 | |||||||
Exhibited significantly reduced general locomotor activity compared to control worms. | Paper_evidence | WBPaper00041959 | ||||||
Curator_confirmed | WBPerson557 | |||||||
WBPhenotype:0000845 | Person_evidence | WBPerson261 | ||||||
Curator_confirmed | WBPerson712 | |||||||
Remark | Uncoordinated but not hypercontracted in 1 mM levamisole. | Person_evidence | WBPerson261 | |||||
Curator_confirmed | WBPerson712 | |||||||
Ease_of_scoring | ES2_Difficult_to_score | Person_evidence | WBPerson261 | |||||
Curator_confirmed | WBPerson712 | |||||||
WBPhenotype:0001315 | Paper_evidence | WBPaper00029130 | ||||||
Curator_confirmed | WBPerson14391 | |||||||
Remark | Reduced conductance of levamisole-sensitive AChRs in muscle. Altered activation kinetics. | Paper_evidence | WBPaper00029130 | |||||
Curator_confirmed | WBPerson14391 | |||||||
WBPhenotype:0001645 | Paper_evidence | WBPaper00004117 | ||||||
Curator_confirmed | WBPerson1754 | |||||||
Remark | Increased levels of protein degradation in muscle in response to starvation | Paper_evidence | WBPaper00004117 | |||||
Curator_confirmed | WBPerson1754 | |||||||
Resistant to levamisole prevention of muscle protein degradation in response to starvation | Paper_evidence | WBPaper00004117 | ||||||
Curator_confirmed | WBPerson1754 | |||||||
WBPhenotype:0001852 | Paper_evidence | WBPaper00035074 | ||||||
Curator_confirmed | WBPerson2021 | |||||||
Remark | Mutants are resistant to tribendimidine | Paper_evidence | WBPaper00035074 | |||||
Curator_confirmed | WBPerson2021 | |||||||
WBPhenotype:0002256 | Paper_evidence | WBPaper00041069 | ||||||
Curator_confirmed | WBPerson1754 | |||||||
Remark | Increased sensitivity to movement decline in response to selenium exposure | Paper_evidence | WBPaper00041069 | |||||
Curator_confirmed | WBPerson1754 | |||||||
Affected_by | Molecule | WBMol:00001915 | Paper_evidence | WBPaper00041069 | ||||
Curator_confirmed | WBPerson1754 | |||||||
Phenotype_not_observed | WBPhenotype:0001853 | Paper_evidence | WBPaper00035150 | |||||
Curator_confirmed | WBPerson2021 | |||||||
Remark | Mutant response to AAD 1470 was comparable to that observed in wild-type | Paper_evidence | WBPaper00035150 | |||||
Curator_confirmed | WBPerson2021 | |||||||
Reference (11) | ||||||||
Method | Allele |