WormBase Tree Display for Variation: WBVar00000004
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WBVar00000004 | Name | Public_name | ad418 | |||||
---|---|---|---|---|---|---|---|---|
Sequence_details | SeqStatus | Pending_curation | ||||||
Variation_type | Allele | |||||||
Origin | Species | Caenorhabditis elegans | ||||||
Laboratory | DA | |||||||
Status | Live | |||||||
Affects | Gene | WBGene00000086 | ||||||
Interactor | WBInteraction000052182 | |||||||
Genetics | Mapping_data | In_2_point | 4467 | |||||
4570 | ||||||||
In_multi_point | 1548 | |||||||
1549 | ||||||||
1586 | ||||||||
Description | Phenotype | WBPhenotype:0000061 | Paper_evidence | WBPaper00024698 | ||||
Curator_confirmed | WBPerson712 | |||||||
Remark | Mean life-span extended by 16%. | Paper_evidence | WBPaper00024698 | |||||
Curator_confirmed | WBPerson712 | |||||||
WBPhenotype:0000204 | Paper_evidence | WBPaper00001709 | ||||||
Curator_confirmed | WBPerson2021 | |||||||
Remark | Defect in the anterior body wall muscle contraction step of the defecation cycle | Paper_evidence | WBPaper00001709 | |||||
Curator_confirmed | WBPerson2021 | |||||||
WBPhenotype:0000650 | Person_evidence | WBPerson261 | ||||||
Curator_confirmed | WBPerson712 | |||||||
Remark | defecation defective | Person_evidence | WBPerson261 | |||||
Curator_confirmed | WBPerson712 | |||||||
WBPhenotype:0000651 | Person_evidence | WBPerson261 | ||||||
Curator_confirmed | WBPerson712 | |||||||
Remark | slightly constipated | Person_evidence | WBPerson261 | |||||
Curator_confirmed | WBPerson712 | |||||||
WBPhenotype:0000996 | Paper_evidence | WBPaper00001709 | ||||||
Curator_confirmed | WBPerson2021 | |||||||
Remark | Defect in the expulsion step of the defecation cycle | Paper_evidence | WBPaper00001709 | |||||
Curator_confirmed | WBPerson2021 | |||||||
WBPhenotype:0001793 | Person_evidence | WBPerson261 | ||||||
Curator_confirmed | WBPerson712 | |||||||
Remark | anterior body contraction (aBoc) and expulsion muscle contraction (Exp) missing in five of six defecation cycles, adult males unaffected and mate well. | Person_evidence | WBPerson261 | |||||
Curator_confirmed | WBPerson712 | |||||||
Phenotype_not_observed | WBPhenotype:0001616 | Paper_evidence | WBPaper00024698 | |||||
Curator_confirmed | WBPerson712 | |||||||
Remark | Trimethadione significantly extended life-span of mutant animals (N=113)(2 ind.exp.), as observed for WT animals. | Paper_evidence | WBPaper00024698 | |||||
Curator_confirmed | WBPerson712 | |||||||
Phenotype_assay | Treatment | Lifespan analysis was performed on animals exposed to 4 mg/ml of the drug from fertilization until death. Animals were cultured on NGM plates containing the drug and seeded with OP50. | Paper_evidence | WBPaper00024698 | ||||
Curator_confirmed | WBPerson712 | |||||||
Temperature | 20°C | Paper_evidence | WBPaper00024698 | |||||
Curator_confirmed | WBPerson712 | |||||||
WBPhenotype:0001617 | Paper_evidence | WBPaper00024698 | ||||||
Curator_confirmed | WBPerson712 | |||||||
Remark | Ethosuximide significantly extended life-span of mutant animals (N=236)(4 ind.exp.), as observed for WT animals. | Paper_evidence | WBPaper00024698 | |||||
Curator_confirmed | WBPerson712 | |||||||
Phenotype_assay | Treatment | Lifespan analysis was performed on animals exposed to 4 mg/ml of the drug from fertilization until death. Animals were cultured on NGM plates containing the drug and seeded with OP50. | Paper_evidence | WBPaper00024698 | ||||
Curator_confirmed | WBPerson712 | |||||||
Temperature | 20°C | Paper_evidence | WBPaper00024698 | |||||
Curator_confirmed | WBPerson712 | |||||||
Reference (6) | ||||||||
Method | Allele |