WormBase Tree Display for Transgene: WBTransgene00005480
expand all nodes | collapse all nodes | view schema
WBTransgene00005480 | Public_name | wyEx1904 | |||||||
---|---|---|---|---|---|---|---|---|---|
Summary | [egl-20::unc-6] | ||||||||
Synonym | (Pegl-20::unc-6#1) | ||||||||
Construction | Construct | WBCnstr00005403 | |||||||
Genetic_information | Extrachromosomal | ||||||||
Phenotype | WBPhenotype:0000384 | Paper_evidence | WBPaper00032163 | ||||||
Curator_confirmed | WBPerson712 | ||||||||
Remark | Ectopic expression of UNC-6/netrin caused DA9 axon guidance defects. | Paper_evidence | WBPaper00032163 | ||||||
Curator_confirmed | WBPerson712 | ||||||||
Penetrance | Incomplete | Paper_evidence | WBPaper00032163 | ||||||
Curator_confirmed | WBPerson712 | ||||||||
Caused_by_gene | WBGene00006746 | Paper_evidence | WBPaper00032163 | ||||||
Curator_confirmed | WBPerson712 | ||||||||
EQ_annotations | Anatomy_term | WBbt:0004857 | PATO:0000460 | Paper_evidence | WBPaper00032163 | ||||
Curator_confirmed | WBPerson712 | ||||||||
WBPhenotype:0000679 | Paper_evidence | WBPaper00032163 | |||||||
Curator_confirmed | WBPerson712 | ||||||||
Remark | GFP::RAB-3 was displaced anteriorly and created an enlarged asynaptic zone in the posterior segment of the DA9 dorsal axon. | Paper_evidence | WBPaper00032163 | ||||||
Curator_confirmed | WBPerson712 | ||||||||
Caused_by_gene | WBGene00006746 | Paper_evidence | WBPaper00032163 | ||||||
Curator_confirmed | WBPerson712 | ||||||||
EQ_annotations | Anatomy_term | WBbt:0004857 | PATO:0000460 | Paper_evidence | WBPaper00032163 | ||||
Curator_confirmed | WBPerson712 | ||||||||
WBPhenotype:0001224 | Paper_evidence | WBPaper00032163 | |||||||
Curator_confirmed | WBPerson712 | ||||||||
Remark | The ectopic expression of UNC-6/netrin does not alter the dorsal axon length of DA9 from that of control animals. | Paper_evidence | WBPaper00032163 | ||||||
Curator_confirmed | WBPerson712 | ||||||||
Caused_by_gene | WBGene00006746 | Paper_evidence | WBPaper00032163 | ||||||
Curator_confirmed | WBPerson712 | ||||||||
EQ_annotations | Anatomy_term | WBbt:0004857 | PATO:0000460 | Paper_evidence | WBPaper00032163 | ||||
Curator_confirmed | WBPerson712 | ||||||||
Phenotype_assay | Genotype | wyEx1902 | Paper_evidence | WBPaper00032163 | |||||
Curator_confirmed | WBPerson712 | ||||||||
WBPhenotype:0001799 | Paper_evidence | WBPaper00032163 | |||||||
Curator_confirmed | WBPerson712 | ||||||||
Remark | Posterior overexpression of UNC-6 created an enlarged asynaptic zone in the posterior segment of the DA9 dorsal axon.The average length of asynaptic regions in DA9 neurons of adults is much greater than that observed for wild-type animals as assayed by the number of GFP::RAB-3 puncta in adult animals. | Paper_evidence | WBPaper00032163 | ||||||
Curator_confirmed | WBPerson712 | ||||||||
Caused_by_gene | WBGene00006746 | Paper_evidence | WBPaper00032163 | ||||||
Curator_confirmed | WBPerson712 | ||||||||
Reference | WBPaper00032163 | ||||||||
Species | Caenorhabditis elegans |