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WormBase Tree Display for Interaction: WBInteraction000542874

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Name Class

WBInteraction000542874Interaction_typeRegulatoryChange_of_localization
InteractorInteractor_overlapping_geneWBGene00011910Interactor_typeTrans_regulator
WBGene00006449Interactor_typeTrans_regulator
WBGene00021113Interactor_typeTrans_regulated
Variation_interactorWBVar00250170Interactor_typeTrans_regulator
WBVar00092311Interactor_typeTrans_regulator
Interaction_summary"Unlike WT spermatozoa, however, these alg-3/4 spermatozoa never formed pseudopods of normal morphology or polarity, with MSP and GSP-3 localized to the leading edge of the pseudopod (Figure 3B). Instead, we observed that (1) MSP and GSP-3 remained in large punctae that resemble sperm organelles called fibrousbodies (FBs) (5%), (2) MSP localized to the cortex and GSP-3 to the cytoplasm of the spermatid but lacked polarity (3%), or (3) GSP-3 remained in the cytoplasm and spermatids formed a multibranched, spikey pseudopod containing MSP (4%)."
Regulation_levelPost_translational
Regulation_resultPositive_regulateLife_stageWBls:0000056
Anatomy_termWBbt:0006799
PaperWBPaper00044616
RemarkFig. 5B; 25C