WormBase Tree Display for Gene: WBGene00022739

WBGene00022739 SMap: S_parent: Sequence: ZK430
  Identity: Version: 2
    Name: CGC_name: toe-1 Person_evidence: WBPerson3232
            WBPerson555
      Sequence_name: ZK430.1
      Molecular_name: ZK430.1
        ZK430.1.1
        CE05078
      Other_name: CELE_ZK430.1 Accession_evidence: NDB BX284602
      Public_name: toe-1
    DB_info: Database: AceView gene 2E721
        WormQTL gene WBGene00022739
        WormFlux gene WBGene00022739
        NDB locus_tag CELE_ZK430.1
        Panther gene CAEEL|WormBase=WBGene00022739|UniProtKB=Q23495
          family PTHR13457
        NCBI gene 173779
        RefSeq protein NM_062381.6
        SwissProt UniProtAcc Q23495
        TREEFAM TREEFAM_ID TF314593
        UniProt_GCRP UniProtAcc Q23495
    Species: Caenorhabditis elegans
    History: Version_change: 1 28 May 2004 13:31:06 WBPerson1971 Event: Imported: Initial conversion from CDS class of stlace from WS125
        2 02 Mar 2009 11:15:07 WBPerson9133 Name_change: CGC_name: toe-1
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: toe
    Allele (117)
    Strain: WBStrain00037372
    RNASeq_FPKM (74)
    GO_annotation (11)
    Ortholog (35)
    Structured_description: Automated_description: Predicted to enable snoRNA binding activity. Predicted to be involved in maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) and positive regulation of transcription by RNA polymerase I. Predicted to be located in nucleolus. Predicted to be part of 90S preribosome; small-subunit processome; and t-UTP complex. Human ortholog(s) of this gene implicated in glioblastoma and pancreatic ductal carcinoma. Is an ortholog of human HEATR1 (HEAT repeat containing 1). Paper_evidence: WBPaper00065943
            WBPaper00067038
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS296 version of WormBase
          Date_last_updated: 20 Mar 2025 00:00:00
  Disease_info: Potential_model: DOID:3068 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:25517)
      DOID:3587 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:25517)
  Molecular_info: Corresponding_CDS: ZK430.1
    Corresponding_transcript: ZK430.1.1
    Other_sequence (24)
    Associated_feature: WBsf644103
      WBsf221125
  Experimental_info: RNAi_result: WBRNAi00026278 Inferred_automatically: RNAi_primary
      WBRNAi00035508 Inferred_automatically: RNAi_primary
      WBRNAi00059425 Inferred_automatically: RNAi_primary
      WBRNAi00027072 Inferred_automatically: RNAi_primary
      WBRNAi00103661 Inferred_automatically: RNAi_primary
      WBRNAi00091014 Inferred_automatically: RNAi_primary
      WBRNAi00082707 Inferred_automatically: RNAi_primary
      WBRNAi00009470 Inferred_automatically: RNAi_primary
      WBRNAi00082391 Inferred_automatically: RNAi_primary
      WBRNAi00009161 Inferred_automatically: RNAi_primary
    Expr_pattern: Expr1016826
      Expr1040053
      Expr1162852
      Expr2017441
      Expr2035580
    Microarray_results (20)
    Expression_cluster (108)
    Interaction (261)
  Map_info: Map: II Position: -4.51525 Error: 0.017392
    Positive: Positive_clone: ZK430 Inferred_automatically: From sequence, transcript, pseudogene data
    Pseudo_map_position
  Reference: WBPaper00032961
    WBPaper00038491
    WBPaper00049828
    WBPaper00055090
    WBPaper00066405
  Remark: Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. CGC_data_submission
  Method: Gene