WormBase Tree Display for Gene: WBGene00021152
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| WBGene00021152 | SMap | S_parent | Sequence | Y4C6A | |||||
|---|---|---|---|---|---|---|---|---|---|
| Identity | Version | 2 | |||||||
| Name | CGC_name | mgl-3 | Paper_evidence | WBPaper00028607 | |||||
| Person_evidence | WBPerson309 | ||||||||
| Sequence_name | Y4C6A.2 | ||||||||
| Molecular_name (21) | |||||||||
| Other_name | CELE_Y4C6A.2 | Accession_evidence | NDB | BX284604 | |||||
| Public_name | mgl-3 | ||||||||
| DB_info | Database (11) | ||||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 28 May 2004 13:31:04 | WBPerson1971 | Event | Imported | Initial conversion from CDS class of stlace from WS125 | ||
| 2 | 01 Nov 2006 11:33:19 | WBPerson1847 | Name_change | CGC_name | mgl-3 | ||||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | mgl | ||||||||
| Allele (101) | |||||||||
| Strain | WBStrain00062524 | ||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation (16) | |||||||||
| Ortholog (52) | |||||||||
| Paralog | WBGene00003232 | Caenorhabditis elegans | From_analysis | TreeFam | |||||
| Panther | |||||||||
| WormBase-Compara | |||||||||
| WBGene00003233 | Caenorhabditis elegans | From_analysis | TreeFam | ||||||
| Panther | |||||||||
| WormBase-Compara | |||||||||
| WBGene00016242 | Caenorhabditis elegans | From_analysis | Panther | ||||||
| WormBase-Compara | |||||||||
| WBGene00018073 | Caenorhabditis elegans | From_analysis | Panther | ||||||
| WormBase-Compara | |||||||||
| Structured_description | Concise_description | mgl-3 encodes one of three C. elegans G protein-coupled metabotropic glutamate receptors; loss of mgl-3 activity reduces the excess fat of daf-7 mutants, indicating that mgl-3 plays a role in regulation of fat accumulation. | Paper_evidence | WBPaper00028607 | |||||
| WBPaper00032082 | |||||||||
| Curator_confirmed | WBPerson1843 | ||||||||
| Date_last_updated | 24 Jun 2014 00:00:00 | ||||||||
| Automated_description | Predicted to enable adenylate cyclase inhibiting G protein-coupled glutamate receptor activity. Involved in positive regulation of lipid storage. Predicted to be located in plasma membrane. Expressed in NSM; head neurons; and nerve ring. Human ortholog(s) of this gene implicated in several diseases, including alcohol dependence; attention deficit hyperactivity disorder; and autistic disorder. Is an ortholog of human GRM8 (glutamate metabotropic receptor 8). | Paper_evidence | WBPaper00065943 | ||||||
| WBPaper00067038 | |||||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS296 version of WormBase | ||||||||
| Date_last_updated | 20 Mar 2025 00:00:00 | ||||||||
| Disease_info | Potential_model | DOID:1094 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:4600) | ||||
| DOID:0050741 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:4600) | ||||||
| DOID:2377 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:4600) | ||||||
| DOID:12849 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:4600) | ||||||
| DOID:0110865 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:4598) | ||||||
| DOID:5419 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:4600) | ||||||
| Molecular_info | Corresponding_CDS | Y4C6A.2a | |||||||
| Y4C6A.2d | |||||||||
| Y4C6A.2e | |||||||||
| Y4C6A.2f | |||||||||
| Y4C6A.2g | |||||||||
| Y4C6A.2h | |||||||||
| Corresponding_CDS_history | Y4C6A.2:wp83 | ||||||||
| Y4C6A.2a:wp240 | |||||||||
| Y4C6A.2b:wp240 | |||||||||
| Y4C6A.2b:wp246 | |||||||||
| Y4C6A.2c:wp240 | |||||||||
| Y4C6A.2c:wp246 | |||||||||
| Y4C6A.2d:wp176 | |||||||||
| Y4C6A.2d:wp240 | |||||||||
| Corresponding_transcript | Y4C6A.2b | ||||||||
| Y4C6A.2c | |||||||||
| Y4C6A.2i | |||||||||
| Y4C6A.2a.1 | |||||||||
| Y4C6A.2d.1 | |||||||||
| Y4C6A.2e.1 | |||||||||
| Y4C6A.2f.1 | |||||||||
| Y4C6A.2g.1 | |||||||||
| Y4C6A.2h.1 | |||||||||
| Other_sequence | GRC04461_1 | ||||||||
| EW743950.1 | |||||||||
| GR17111 | |||||||||
| MH07985 | |||||||||
| PPC18921_1 | |||||||||
| JI466943.1 | |||||||||
| JI165283.1 | |||||||||
| ACC23182_1 | |||||||||
| Associated_feature | WBsf996505 | ||||||||
| WBsf228308 | |||||||||
| Experimental_info | RNAi_result | WBRNAi00024159 | Inferred_automatically | RNAi_primary | |||||
| WBRNAi00020814 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00023872 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00020813 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00057056 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00023359 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00024234 | Inferred_automatically | RNAi_primary | |||||||
| Expr_pattern | Expr8247 | ||||||||
| Expr11451 | |||||||||
| Expr12338 | |||||||||
| Expr15388 | |||||||||
| Expr1014032 | |||||||||
| Expr1039227 | |||||||||
| Expr1160499 | |||||||||
| Expr2013552 | |||||||||
| Expr2031785 | |||||||||
| Drives_construct | WBCnstr00013208 | ||||||||
| WBCnstr00018854 | |||||||||
| WBCnstr00020792 | |||||||||
| WBCnstr00024663 | |||||||||
| Construct_product | WBCnstr00024663 | ||||||||
| Microarray_results (39) | |||||||||
| Expression_cluster (134) | |||||||||
| Interaction | WBInteraction000504302 | ||||||||
| Map_info | Map | IV | Position | 1.67826 | |||||
| Positive | Positive_clone | Y4C6A | Inferred_automatically | From sequence, transcript, pseudogene data | |||||
| Pseudo_map_position | |||||||||
| Reference (12) | |||||||||
| Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||||
| [140923 pad] Modified Map position as it was a reverse physical that could not be fixed by automated methods. | |||||||||
| Method | Gene |
