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WormBase Tree Display for Gene: WBGene00020951

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Name Class

WBGene00020951SMapS_parentSequenceW02F12
IdentityVersion2
NameCGC_namesna-1Person_evidenceWBPerson71
Sequence_nameW02F12.6
Molecular_nameW02F12.6
W02F12.6.1
CE31084
Other_nameCELE_W02F12.6Accession_evidenceNDBBX284605
Public_namesna-1
DB_infoDatabaseAceViewgene5H190
WormQTLgeneWBGene00020951
WormFluxgeneWBGene00020951
NDBlocus_tagCELE_W02F12.6
PanthergeneCAEEL|WormBase=WBGene00020951|UniProtKB=O45149
familyPTHR13104
NCBIgene179064
RefSeqproteinNM_072300.7
TREEFAMTREEFAM_IDTF343425
TrEMBLUniProtAccO45149
UniProt_GCRPUniProtAccO45149
SpeciesCaenorhabditis elegans
HistoryVersion_change128 May 2004 13:31:03WBPerson1971EventImportedInitial conversion from CDS class of stlace from WS125
205 Dec 2006 15:46:53WBPerson1847Name_changeCGC_namesna-1
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classsna
Allele (25)
Possibly_affected_byWBVar02158598
RNASeq_FPKM (74)
GO_annotation00035391
00035392
00035393
00035394
00035395
Contained_in_operonCEOP5132
Ortholog (25)
ParalogWBGene00003164Caenorhabditis elegansFrom_analysisPanther
WBGene00020475Caenorhabditis elegansFrom_analysisTreeFam
Structured_descriptionConcise_descriptionsna-1 encodes an snRNP-binding protein (SNA-1/SL21p) orthologous toAscaris SL30p (SL 30kd) and Brugia 13258.m00169, and paralogous toBrugia 14704.m00455; SNA-1 is found in the Sm snRNP SL1, but not in SL2;in snRNP SL1, SNA-1 associates with the SNA-2/SL75p protein, while beingreplaced by SUT-1/SL26p (a paralog of SNA-1) in snRNP Y; sna-1(RNAi)animals, like sut-1(bk79) mutants, have cold-sensitive sterility,whereas sna-1(RNAi) combined with sut-1(bk79) is synthetically lethal;double sna-1(RNAi) sut-1(RNAi) is lethal; these RNAi data indicate thatSNA-1 and SUT-1 are partially redundant, and suggest that snRNP Y (likesnRNP SL1) may participate in trans-splicing; SNA-1 can bind SNA-2 evenin the absence of RNA.Paper_evidenceWBPaper00029092
WBPaper00029095
WBPaper00029096
Curator_confirmedWBPerson567
Date_last_updated11 Feb 2007 00:00:00
Automated_descriptionPredicted to enable transcription coactivator activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be part of core mediator complex and mediator complex. Expressed in several structures, including germ cell and somatic cell.Paper_evidenceWBPaper00065943
WBPaper00067038
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS296 version of WormBase
Date_last_updated20 Mar 2025 00:00:00
Molecular_infoCorresponding_CDSW02F12.6
Corresponding_transcriptW02F12.6.1
Other_sequenceCBC05314_1
CR00422
CRC05434_1
CRC11360_1
Associated_featureWBsf652732
WBsf233857
Experimental_infoRNAi_resultWBRNAi00062396Inferred_automaticallyRNAi_primary
WBRNAi00054620Inferred_automaticallyRNAi_primary
WBRNAi00019512Inferred_automaticallyRNAi_primary
WBRNAi00103558Inferred_automaticallyRNAi_primary
WBRNAi00065828Inferred_automaticallyRNAi_primary
WBRNAi00036205Inferred_automaticallyRNAi_primary
WBRNAi00065827Inferred_automaticallyRNAi_primary
Expr_patternExpr16316
Expr1023577
Expr1039129
Expr1158164
Expr2015934
Expr2034167
Drives_constructWBCnstr00024761
Construct_productWBCnstr00024761
Regulate_expr_clusterWBPaper00064201:SNA-1_interacting
AntibodyWBAntibody00001225
Microarray_results (18)
Expression_cluster (124)
Interaction (70)
Map_infoMapVPosition0.134485Error8.3e-05
PositivePositive_cloneW02F12Inferred_automaticallyFrom sequence, transcript, pseudogene data
Pseudo_map_position
ReferenceWBPaper00029092
WBPaper00033621
WBPaper00051343
WBPaper00063447
WBPaper00064201
WBPaper00065308
RemarkMap position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.CGC_data_submission
MethodGene