WormBase Tree Display for Gene: WBGene00020658
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| WBGene00020658 | SMap | S_parent | Sequence | T21F4 | |||||
|---|---|---|---|---|---|---|---|---|---|
| Identity | Version | 2 | |||||||
| Name | CGC_name | argn-1 | Person_evidence | WBPerson2241 | |||||
| Sequence_name | T21F4.1 | ||||||||
| Molecular_name | T21F4.1 | ||||||||
| T21F4.1.1 | |||||||||
| CE33700 | |||||||||
| T21F4.1.2 | |||||||||
| Other_name | CELE_T21F4.1 | Accession_evidence | NDB | BX284606 | |||||
| Public_name | argn-1 | ||||||||
| DB_info | Database (12) | ||||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 28 May 2004 13:31:03 | WBPerson1971 | Event | Imported | Initial conversion from CDS class of stlace from WS125 | ||
| 2 | 02 Mar 2020 15:36:25 | WBPerson1983 | Name_change | CGC_name | argn-1 | ||||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | argn | ||||||||
| Allele (36) | |||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation | 00002978 | ||||||||
| 00002979 | |||||||||
| 00002980 | |||||||||
| 00002981 | |||||||||
| 00002982 | |||||||||
| 00002983 | |||||||||
| 00002984 | |||||||||
| 00129147 | |||||||||
| Ortholog (35) | |||||||||
| Structured_description | Concise_description | T21F4.1 is orthologous to the human gene Arginase Type I Erythroid Variant (ARG1), which contributes most of the arginase activity in the liver. | Paper_evidence | WBPaper00038491 | |||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson1823 | |||||||||
| WBPerson567 | |||||||||
| Date_last_updated | 19 Jun 2012 00:00:00 | ||||||||
| Automated_description | Predicted to enable arginase activity and manganese ion binding activity. Involved in innate immune response. Predicted to be located in cytosol. Expressed in hypodermal cell. Used to study hyperargininemia. Human ortholog(s) of this gene implicated in several diseases, including colitis; hepatocellular carcinoma; and hyperargininemia. Is an ortholog of human ARG1 (arginase 1) and ARG2 (arginase 2). | Paper_evidence | WBPaper00065943 | ||||||
| WBPaper00067038 | |||||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS296 version of WormBase | ||||||||
| Date_last_updated | 20 Mar 2025 00:00:00 | ||||||||
| Disease_info | Experimental_model | DOID:9278 | Homo sapiens | Paper_evidence | WBPaper00059575 | ||||
| Curator_confirmed | WBPerson324 | ||||||||
| Date_last_updated | 09 Jun 2021 00:00:00 | ||||||||
| Potential_model | DOID:9278 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:663) | |||||
| DOID:2841 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:663,HGNC:664) | ||||||
| DOID:0060180 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:663) | ||||||
| DOID:684 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:663) | ||||||
| Models_disease_in_annotation | WBDOannot00000944 | ||||||||
| Models_disease_asserted | WBDOannot00000943 | ||||||||
| Molecular_info | Corresponding_CDS | T21F4.1 | |||||||
| Corresponding_CDS_history | T21F4.1:wp97 | ||||||||
| T21F4.1:wp225 | |||||||||
| T21F4.1a:wp259 | |||||||||
| T21F4.1b:wp259 | |||||||||
| Corresponding_transcript | T21F4.1.1 | ||||||||
| T21F4.1.2 | |||||||||
| Other_sequence (50) | |||||||||
| Associated_feature (12) | |||||||||
| Experimental_info | RNAi_result | WBRNAi00018988 | Inferred_automatically | RNAi_primary | |||||
| WBRNAi00053755 | Inferred_automatically | RNAi_primary | |||||||
| Expr_pattern | Expr16081 | ||||||||
| Expr16082 | |||||||||
| Expr1029161 | |||||||||
| Expr1038997 | |||||||||
| Expr1157304 | |||||||||
| Expr2006332 | |||||||||
| Expr2024552 | |||||||||
| Drives_construct | WBCnstr00042752 | ||||||||
| WBCnstr00042753 | |||||||||
| Construct_product | WBCnstr00042753 | ||||||||
| Microarray_results (21) | |||||||||
| Expression_cluster (218) | |||||||||
| Interaction (48) | |||||||||
| Map_info | Map | X | Position | -4.42581 | |||||
| Positive | Positive_clone | T21F4 | Inferred_automatically | From sequence, transcript, pseudogene data | |||||
| Pseudo_map_position | |||||||||
| Reference | WBPaper00038491 | ||||||||
| WBPaper00055090 | |||||||||
| WBPaper00059575 | |||||||||
| Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||||
| Method | Gene |
