WormBase Tree Display for Gene: WBGene00020282
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| WBGene00020282 | SMap | S_parent | Sequence | T06A4 | |||||
|---|---|---|---|---|---|---|---|---|---|
| Identity | Version | 2 | |||||||
| Name | CGC_name | mps-3 | Person_evidence | WBPerson3192 | |||||
| Sequence_name | T06A4.2 | ||||||||
| Molecular_name | T06A4.2 | ||||||||
| T06A4.2.1 | |||||||||
| CE29464 | |||||||||
| Other_name | CELE_T06A4.2 | Accession_evidence | NDB | BX284601 | |||||
| Public_name | mps-3 | ||||||||
| DB_info | Database | AceView | gene | 1B234 | |||||
| WormQTL | gene | WBGene00020282 | |||||||
| WormFlux | gene | WBGene00020282 | |||||||
| NDB | locus_tag | CELE_T06A4.2 | |||||||
| NCBI | gene | 188157 | |||||||
| RefSeq | protein | NM_058377.4 | |||||||
| TrEMBL | UniProtAcc | G5ECI4 | |||||||
| UniProt_GCRP | UniProtAcc | G5ECI4 | |||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 28 May 2004 13:31:02 | WBPerson1971 | Event | Imported | Initial conversion from CDS class of stlace from WS125 | ||
| 2 | 12 Jul 2005 16:22:27 | WBPerson2970 | Name_change | CGC_name | mps-3 | ||||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | mps | ||||||||
| Allele (18) | |||||||||
| Strain | WBStrain00032348 | ||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation | 00012351 | ||||||||
| 00012352 | |||||||||
| 00012353 | |||||||||
| 00012354 | |||||||||
| 00012355 | |||||||||
| Ortholog (15) | |||||||||
| Structured_description | Concise_description | mps-3 encodes a single-pass transmembrane protein that is related to the vertebrate KCNE proteins, also known as MinK-related peptides (MiRPs) that associate with, and regulate, pore-forming ion channels; mps-1 is required for the normal function of several neurons and thus for normal body touch sensation, chemotaxis to select molecules, osmotic avoidance, and nose-touch; when coexpressed in tissue culture cells with C. elegans KVS-1, MPS-3 is able to alter the activity of this potassium-selective channel, suggesting that MPS-3 functions in vivo to regulate KVS-1 activity in neurons in which the two proteins are coexpressed; in addition, activity of MPS-2, MPS-3, and KVS-1 coexpressed in culture suggests that these three proteins can form a functional ternary complex that genetic analyses indicate likely plays a role in regulating responsiveness to sodium; MPS-3 reporter fusions are expressed in the ADF amphid sensory neuron, the PVC and PVN neurons, and two neurons in the anterior bulb of the pharynx. | Paper_evidence | WBPaper00025063 | |||||
| Curator_confirmed | WBPerson1843 | ||||||||
| Date_last_updated | 11 May 2007 00:00:00 | ||||||||
| Automated_description | Enables potassium channel regulator activity. Involved in regulation of chemotaxis and regulation of potassium ion transport. Predicted to be located in membrane. Expressed in ADF; lumbar neurons; and pharyngeal neurons. | Paper_evidence | WBPaper00065943 | ||||||
| WBPaper00067038 | |||||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS296 version of WormBase | ||||||||
| Date_last_updated | 20 Mar 2025 00:00:00 | ||||||||
| Molecular_info | Corresponding_CDS | T06A4.2 | |||||||
| Corresponding_transcript | T06A4.2.1 | ||||||||
| Associated_feature | WBsf982566 | ||||||||
| WBsf218935 | |||||||||
| Experimental_info | RNAi_result | WBRNAi00035249 | Inferred_automatically | RNAi_primary | |||||
| WBRNAi00052613 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00004147 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00085210 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00085207 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00085214 | Inferred_automatically | RNAi_primary | |||||||
| Expr_pattern | Expr3267 | ||||||||
| Expr1019367 | |||||||||
| Expr1156219 | |||||||||
| Expr2013673 | |||||||||
| Expr2031907 | |||||||||
| Drives_construct | WBCnstr00011270 | ||||||||
| WBCnstr00025242 | |||||||||
| Construct_product | WBCnstr00011270 | ||||||||
| WBCnstr00025242 | |||||||||
| Microarray_results (16) | |||||||||
| Expression_cluster (160) | |||||||||
| Interaction | WBInteraction000335768 | ||||||||
| WBInteraction000554835 | |||||||||
| WBInteraction000555998 | |||||||||
| WBInteraction000555999 | |||||||||
| Map_info | Map | I | Position | -18.2871 | Error | 0.040091 | |||
| Positive | Positive_clone | T06A4 | Inferred_automatically | From sequence, transcript, pseudogene data | |||||
| Pseudo_map_position | |||||||||
| Reference | WBPaper00025063 | ||||||||
| WBPaper00028450 | |||||||||
| WBPaper00052591 | |||||||||
| Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||||
| Method | Gene |
