WormBase Tree Display for Gene: WBGene00020046

WBGene00020046 SMap: S_parent: Sequence: R13A1
  Identity: Version: 2
    Name: CGC_name: best-16 Person_evidence: WBPerson260
      Sequence_name: R13A1.9
      Molecular_name: R13A1.9
        R13A1.9.1
        CE49408
      Other_name: R13A1.c Curator_confirmed: WBPerson1983
          Remark: Old cosmid naming mapped via unique overlapping PCR_product on CDSs
        CELE_R13A1.9 Accession_evidence: NDB BX284604
      Public_name: best-16
    DB_info: Database: AceView gene 4H956
        WormQTL gene WBGene00020046
        WormFlux gene WBGene00020046
        NDB locus_tag CELE_R13A1.9
        Panther gene CAEEL|WormBase=WBGene00020046|UniProtKB=Q7YXH3
          family PTHR10736
        NCBI gene 3565658
        RefSeq protein NM_001028173.5
        TrEMBL UniProtAcc Q7YXH3
        UniProt_GCRP UniProtAcc Q7YXH3
        OMIM gene 607854
    Species: Caenorhabditis elegans
    History: Version_change: 1 28 May 2004 13:31:02 WBPerson1971 Event: Imported: Initial conversion from CDS class of stlace from WS125
        2 07 Feb 2012 16:30:56 WBPerson2970 Name_change: CGC_name: best-16
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: best
    Allele (26)
    RNASeq_FPKM (74)
    GO_annotation: 00078706
      00078707
      00078708
      00078709
      00078710
      00078711
      00078712
      00078713
      00119520
    Ortholog (33)
    Paralog (26)
    Structured_description: Automated_description: Predicted to enable chloride channel activity. Predicted to be involved in chloride transmembrane transport. Predicted to be located in plasma membrane. Predicted to be part of chloride channel complex. Human ortholog(s) of this gene implicated in autosomal dominant vitreoretinochoroidopathy and retinal degeneration (multiple). Is an ortholog of several human genes including BEST1 (bestrophin 1); BEST2 (bestrophin 2); and BEST3 (bestrophin 3). Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS292 version of WormBase
          Date_last_updated: 24 Apr 2024 00:00:00
  Disease_info: Potential_model: DOID:0110396 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:12703)
      DOID:4448 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:12703)
      DOID:0050661 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:12703)
      DOID:0050662 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:12703)
      DOID:0111569 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:12703)
  Molecular_info: Corresponding_CDS: R13A1.9
    Corresponding_CDS_history: R13A1.9:wp143
      R13A1.9:wp240
    Corresponding_transcript: R13A1.9.1
  Experimental_info: RNAi_result: WBRNAi00034911 Inferred_automatically: RNAi_primary
    Expr_pattern: Expr1011133
      Expr1155540
    Drives_construct: WBCnstr00025405
    Construct_product: WBCnstr00025405
    Microarray_results (12)
    Expression_cluster (59)
  Map_info: Map: IV Position: 3.29294
    Positive: Positive_clone: R13A1 Inferred_automatically: From sequence, transcript, pseudogene data
    Pseudo_map_position
  Reference: WBPaper00038491
    WBPaper00055090
  Remark: Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. CGC_data_submission
  Method: Gene