WormBase Tree Display for Gene: WBGene00020007
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WBGene00020007 | SMap | S_parent | Sequence | R11F4 | |||||
---|---|---|---|---|---|---|---|---|---|
Identity | Version | 1 | |||||||
Name | Sequence_name | R11F4.1 | |||||||
Molecular_name | R11F4.1 | ||||||||
R11F4.1.1 | |||||||||
CE04828 | |||||||||
Other_name | R11F4.a | Curator_confirmed | WBPerson1983 | ||||||
Remark | Old cosmid naming mapped via unique overlapping PCR_product on CDSs | ||||||||
CELE_R11F4.1 | Accession_evidence | NDB | BX284602 | ||||||
Public_name | R11F4.1 | ||||||||
DB_info | Database (13) | ||||||||
Species | Caenorhabditis elegans | ||||||||
History | Version_change | 1 | 28 May 2004 13:31:02 | WBPerson1971 | Event | Imported | Initial conversion from CDS class of stlace from WS125 | ||
Status | Live | ||||||||
Gene_info | Biotype | SO:0001217 | |||||||
Allele (47) | |||||||||
RNASeq_FPKM (74) | |||||||||
GO_annotation (15) | |||||||||
Ortholog (45) | |||||||||
Paralog | WBGene00011147 | Caenorhabditis elegans | From_analysis | Panther | |||||
WormBase-Compara | |||||||||
WBGene00012017 | Caenorhabditis elegans | From_analysis | Panther | ||||||
WBGene00016939 | Caenorhabditis elegans | From_analysis | Panther | ||||||
WormBase-Compara | |||||||||
Structured_description | Concise_description | The R11F4.1 gene encodes a putative glycerol kinase and is orthologous to human glycerol kinase (GK); glycerol kinase catalyses the phosphorylation of glycerol to glycerol-3 phosphate; in elegans, glycerol kinase is enriched in the dauer stage and is one of several genes involved in energy metabolism that are upregulated, when worms are grown in a nutrient deficient medium. | Paper_evidence | WBPaper00004103 | |||||
WBPaper00031648 | |||||||||
WBPaper00005859 | |||||||||
Curator_confirmed | WBPerson567 | ||||||||
WBPerson324 | |||||||||
Date_last_updated | 27 Aug 2012 00:00:00 | ||||||||
Automated_description | Predicted to enable glycerol kinase activity. Predicted to be involved in glycerol metabolic process; glycerol-3-phosphate biosynthetic process; and triglyceride metabolic process. Predicted to be located in mitochondrion. Human ortholog(s) of this gene implicated in glycerol kinase deficiency. Is an ortholog of human GK (glycerol kinase); GK2 (glycerol kinase 2); and GK3 (glycerol kinase 3). | Paper_evidence | WBPaper00065943 | ||||||
Curator_confirmed | WBPerson324 | ||||||||
WBPerson37462 | |||||||||
Inferred_automatically | This description was generated automatically by a script based on data from the WS292 version of WormBase | ||||||||
Date_last_updated | 24 Apr 2024 00:00:00 | ||||||||
Disease_info | Potential_model | DOID:0060363 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:4289) | ||||
Disease_relevance | R11F4.1 is orthologous to human glycerol kinase, which when mutated causes glycerol kinase deficiency, leading to hyperglycerolemia. | Homo sapiens | Accession_evidence | OMIM | 307030 | ||||
300474 | |||||||||
Curator_confirmed | WBPerson324 | ||||||||
Date_last_updated | 27 Aug 2012 00:00:00 | ||||||||
Molecular_info | Corresponding_CDS | R11F4.1 | |||||||
Corresponding_transcript | R11F4.1.1 | ||||||||
Other_sequence (158) | |||||||||
Associated_feature (18) | |||||||||
Experimental_info | RNAi_result | WBRNAi00001325 | Inferred_automatically | RNAi_primary | |||||
WBRNAi00051795 | Inferred_automatically | RNAi_primary | |||||||
WBRNAi00001756 | Inferred_automatically | RNAi_primary | |||||||
WBRNAi00001439 | Inferred_automatically | RNAi_primary | |||||||
WBRNAi00017755 | Inferred_automatically | RNAi_primary | |||||||
WBRNAi00034863 | Inferred_automatically | RNAi_primary | |||||||
Expr_pattern | Chronogram446 | ||||||||
Expr6508 | |||||||||
Expr1012336 | |||||||||
Expr1038688 | |||||||||
Expr1155456 | |||||||||
Expr2005589 | |||||||||
Expr2023807 | |||||||||
Drives_construct | WBCnstr00003958 | ||||||||
WBCnstr00025437 | |||||||||
Construct_product | WBCnstr00025437 | ||||||||
Microarray_results (23) | |||||||||
Expression_cluster (226) | |||||||||
Interaction (130) | |||||||||
Map_info | Positive | Positive_clone | R11F4 | Inferred_automatically | From sequence, transcript, pseudogene data | ||||
Interpolated_map_position | II | -5.62873 | |||||||
Reference | WBPaper00031648 | ||||||||
WBPaper00038491 | |||||||||
WBPaper00042257 | |||||||||
WBPaper00055090 | |||||||||
Method | Gene |