WormBase Tree Display for Gene: WBGene00016803
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| WBGene00016803 | SMap | S_parent | Sequence | C50C3 | |||||
|---|---|---|---|---|---|---|---|---|---|
| Identity | Version | 2 | |||||||
| Name | CGC_name | bath-42 | Person_evidence | WBPerson655 | |||||
| Sequence_name | C50C3.8 | ||||||||
| Molecular_name | C50C3.8 | ||||||||
| C50C3.8.1 | |||||||||
| CE00124 | |||||||||
| Other_name | CELE_C50C3.8 | Accession_evidence | NDB | BX284603 | |||||
| Public_name | bath-42 | ||||||||
| DB_info | Database (11) | ||||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 28 May 2004 13:30:57 | WBPerson1971 | Event | Imported | Initial conversion from CDS class of stlace from WS125 | ||
| 2 | 22 Aug 2005 16:08:42 | WBPerson2970 | Name_change | CGC_name | bath-42 | ||||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | bath | ||||||||
| Allele (25) | |||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation | 00043867 | ||||||||
| 00043868 | |||||||||
| 00043869 | |||||||||
| 00043870 | |||||||||
| 00043871 | |||||||||
| 00043872 | |||||||||
| 00043873 | |||||||||
| 00043874 | |||||||||
| Contained_in_operon | CEOP3484 | ||||||||
| Ortholog (45) | |||||||||
| Paralog | WBGene00003209 | Caenorhabditis elegans | From_analysis | Panther | |||||
| WormBase-Compara | |||||||||
| WBGene00011815 | Caenorhabditis elegans | From_analysis | Panther | ||||||
| WormBase-Compara | |||||||||
| WBGene00015567 | Caenorhabditis elegans | From_analysis | Panther | ||||||
| WBGene00018137 | Caenorhabditis elegans | From_analysis | Panther | ||||||
| WBGene00006415 | Caenorhabditis elegans | From_analysis | WormBase-Compara | ||||||
| WBGene00013689 | Caenorhabditis elegans | From_analysis | WormBase-Compara | ||||||
| WBGene00015463 | Caenorhabditis elegans | From_analysis | WormBase-Compara | ||||||
| Structured_description | Concise_description | bath-42 encodes a BTB (broad-complex, Tramtrack, and bric-a-brac) and MATH (meprin-associated Traf homology) domain-containing protein; loss of bath-42 function results in increased levels of the RIC-3 nicotinic acetylcholine receptor (nAChR)-specific chaperone in vulval muscles and decreased egg-laying in response to treatment with levamisole, an nAChR agonist; in addition, overexpression of BATH-42 results in decreased pharyngeal pumping, in a manner dependent upon the presence of the RIC-3 C-terminus and the CUL-3 cullin; as BATH-42 interacts in vitro with both CUL-3 and the RIC-3 C-terminus, BATH-42 likely functions to regulate RIC-3 levels via CUL-3-mediated ubiquitination and degradation; bath-42::gfp promoter fusions are expressed in vulval and pharyngeal muscles, some head and body neurons, the posterior intestine, and hypodermal seam cells. | Paper_evidence | WBPaper00004589 | |||||
| WBPaper00006055 | |||||||||
| WBPaper00032915 | |||||||||
| Curator_confirmed | WBPerson1843 | ||||||||
| WBPerson567 | |||||||||
| Date_last_updated | 19 Feb 2009 00:00:00 | ||||||||
| Automated_description | Predicted to enable ubiquitin protein ligase binding activity. Predicted to be involved in proteasome-mediated ubiquitin-dependent protein catabolic process and regulation of proteolysis. Predicted to be located in cytoplasm and nucleus. Expressed in intestine; pharyngeal muscle cell; seam cell; and vulval muscle. | Paper_evidence | WBPaper00065943 | ||||||
| WBPaper00067038 | |||||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS296 version of WormBase | ||||||||
| Date_last_updated | 20 Mar 2025 00:00:00 | ||||||||
| Molecular_info | Corresponding_CDS | C50C3.8 | |||||||
| Corresponding_transcript | C50C3.8.1 | ||||||||
| Other_sequence (32) | |||||||||
| Associated_feature | WBsf667139 | ||||||||
| WBsf667140 | |||||||||
| WBsf227091 | |||||||||
| Experimental_info | RNAi_result | WBRNAi00030019 | Inferred_automatically | RNAi_primary | |||||
| WBRNAi00005446 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00012200 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00007778 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00078506 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00078840 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00077821 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00042877 | Inferred_automatically | RNAi_primary | |||||||
| Expr_pattern | Chronogram400 | ||||||||
| Expr5549 | |||||||||
| Expr8532 | |||||||||
| Expr1022637 | |||||||||
| Expr1037212 | |||||||||
| Expr1146856 | |||||||||
| Expr2009559 | |||||||||
| Expr2027796 | |||||||||
| Drives_construct | WBCnstr00002927 | ||||||||
| WBCnstr00013350 | |||||||||
| WBCnstr00027794 | |||||||||
| Construct_product | WBCnstr00027794 | ||||||||
| Microarray_results (22) | |||||||||
| Expression_cluster (142) | |||||||||
| Interaction (224) | |||||||||
| Map_info | Map | III | Position | -0.374511 | Error | 0.00019 | |||
| Positive | Positive_clone | C50C3 | Inferred_automatically | From sequence, transcript, pseudogene data | |||||
| Pseudo_map_position | |||||||||
| Reference | WBPaper00017263 | ||||||||
| WBPaper00032915 | |||||||||
| WBPaper00035231 | |||||||||
| WBPaper00035381 | |||||||||
| WBPaper00055090 | |||||||||
| WBPaper00060694 | |||||||||
| Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||||
| Method | Gene |
