WormBase Tree Display for Gene: WBGene00013878
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WBGene00013878 | SMap | S_parent | Sequence | CHROMOSOME_V | |||||
---|---|---|---|---|---|---|---|---|---|
Identity | Version | 2 | |||||||
Name | CGC_name | atfs-1 | Person_evidence | WBPerson9073 | |||||
Sequence_name | ZC376.7 | ||||||||
Molecular_name (15) | |||||||||
Other_name | CELE_ZC376.7 | Accession_evidence | NDB | BX284605 | |||||
Public_name | atfs-1 | ||||||||
DB_info | Database | AceView | gene | 5O677 | |||||
WormQTL | gene | WBGene00013878 | |||||||
WormFlux | gene | WBGene00013878 | |||||||
NDB | locus_tag | CELE_ZC376.7 | |||||||
Panther | gene | CAEEL|WormBase=WBGene00013878|UniProtKB=Q23272 | |||||||
family | PTHR13044 | ||||||||
NCBI | gene | 179922 | |||||||
RefSeq | protein | NM_001269642.3 | |||||||
NM_182360.9 | |||||||||
NM_074114.7 | |||||||||
NM_001029131.6 | |||||||||
SwissProt | UniProtAcc | Q23272 | |||||||
TREEFAM | TREEFAM_ID | TF315772 | |||||||
UniProt_GCRP | UniProtAcc | Q23272 | |||||||
Species | Caenorhabditis elegans | ||||||||
History | Version_change | 1 | 26 May 2004 16:54:55 | WBPerson1971 | Event | Imported | Initial conversion from CDS class of WS125 | ||
2 | 24 May 2011 10:23:31 | WBPerson2970 | Name_change | CGC_name | atfs-1 | ||||
Status | Live | ||||||||
Gene_info | Biotype | SO:0001217 | |||||||
Gene_class | atfs | ||||||||
Allele (102) | |||||||||
Strain | WBStrain00031161 | ||||||||
WBStrain00031162 | |||||||||
WBStrain00031163 | |||||||||
WBStrain00031164 | |||||||||
WBStrain00037720 | |||||||||
WBStrain00052571 | |||||||||
WBStrain00052572 | |||||||||
WBStrain00052468 | |||||||||
RNASeq_FPKM (74) | |||||||||
GO_annotation (67) | |||||||||
Ortholog (23) | |||||||||
Paralog | WBGene00000221 | Caenorhabditis elegans | From_analysis | Panther | |||||
WormBase-Compara | |||||||||
WBGene00007932 | Caenorhabditis elegans | From_analysis | Panther | ||||||
WBGene00012330 | Caenorhabditis elegans | From_analysis | Panther | ||||||
WBGene00077761 | Caenorhabditis elegans | From_analysis | Panther | ||||||
Structured_description | Concise_description | atfs-1 encodes a bZip transcription factor; ATFS-1 is required for the mitochondrial unfolded protein response (UPRmt); in wild-type animals, ATFS-1 is imported into the mitochondria and degraded, but in response to perturbed mitchondrial protein folding and decreased mitochondrial import efficiency, some ATFS-1 accumulates in the cytosol and then, traffics to the nucleus. | Paper_evidence | WBPaper00035985 | |||||
WBPaper00041370 | |||||||||
Curator_confirmed | WBPerson1843 | ||||||||
Date_last_updated | 23 Oct 2012 00:00:00 | ||||||||
Automated_description | Enables DNA-binding transcription factor activity, RNA polymerase II-specific; enzyme binding activity; and mitochondrial transcription factor activity. Involved in positive regulation of nematode larval development; regulation of gene expression; and response to stress. Located in mitochondrial matrix and nucleus. Human ortholog(s) of this gene implicated in prostate carcinoma. Is an ortholog of human ATF4 (activating transcription factor 4). | Paper_evidence | WBPaper00065943 | ||||||
Curator_confirmed | WBPerson324 | ||||||||
WBPerson37462 | |||||||||
Inferred_automatically | This description was generated automatically by a script based on data from the WS292 version of WormBase | ||||||||
Date_last_updated | 24 Apr 2024 00:00:00 | ||||||||
Disease_info | Potential_model | DOID:10286 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:786) | ||||
Molecular_info | Corresponding_CDS | ZC376.7a | |||||||
ZC376.7b | |||||||||
ZC376.7c | |||||||||
ZC376.7d | |||||||||
Corresponding_CDS_history | ZC376.7:wp87 | ||||||||
Corresponding_transcript | ZC376.7a.1 | ||||||||
ZC376.7a.2 | |||||||||
ZC376.7b.1 | |||||||||
ZC376.7b.2 | |||||||||
ZC376.7c.1 | |||||||||
ZC376.7c.2 | |||||||||
ZC376.7d.1 | |||||||||
Other_sequence | CJC10202_1 | ||||||||
CR05510 | |||||||||
CJC00946_1 | |||||||||
CR05812 | |||||||||
MH00118 | |||||||||
Hbac_isotig01486 | |||||||||
CRC00297_1 | |||||||||
CBC02450_1 | |||||||||
Associated_feature (16) | |||||||||
Gene_product_binds | WBsf980914 | ||||||||
Transcription_factor | WBTranscriptionFactor000444 | ||||||||
Experimental_info | RNAi_result (55) | ||||||||
Expr_pattern | Expr8935 | ||||||||
Expr9728 | |||||||||
Expr9743 | |||||||||
Expr1015095 | |||||||||
Expr1036209 | |||||||||
Expr1162304 | |||||||||
Expr2009484 | |||||||||
Expr2027721 | |||||||||
Drives_construct | WBCnstr00013629 | ||||||||
WBCnstr00014248 | |||||||||
WBCnstr00014263 | |||||||||
WBCnstr00029481 | |||||||||
Construct_product | WBCnstr00013629 | ||||||||
WBCnstr00021929 | |||||||||
WBCnstr00029481 | |||||||||
WBCnstr00038813 | |||||||||
Regulate_expr_cluster (12) | |||||||||
Antibody | WBAntibody00002652 | ||||||||
Microarray_results (32) | |||||||||
Expression_cluster (116) | |||||||||
Interaction (975) | |||||||||
WBProcess | WBbiopr:00000077 | ||||||||
WBbiopr:00000079 | |||||||||
Map_info | Map | V | Position | 6.19651 | Error | 0.002029 | |||
Positive | Positive_clone | ZC376 | Inferred_automatically | From sequence, transcript, pseudogene data | |||||
Pseudo_map_position | |||||||||
Reference (127) | |||||||||
Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||||
Method | Gene |