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WormBase Tree Display for Gene: WBGene00013049

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Name Class

WBGene00013049SMapS_parentSequenceY50E8A
IdentityVersion1
NameSequence_nameY50E8A.6
Molecular_nameY50E8A.6
Y50E8A.6.1
CE40165
Other_nameCELE_Y50E8A.6Accession_evidenceNDBBX284605
Public_nameY50E8A.6
DB_infoDatabase (13)
SpeciesCaenorhabditis elegans
HistoryVersion_change126 May 2004 16:54:54WBPerson1971EventImportedInitial conversion from CDS class of WS125
StatusLive
Gene_infoBiotypeSO:0001217
Allele (40)
RNASeq_FPKM (74)
GO_annotation (11)
Ortholog (35)
ParalogWBGene00012031Caenorhabditis elegansFrom_analysisPanther
WormBase-Compara
Structured_descriptionConcise_descriptionY50E8A.6 encodes a putative mitochondrial glycerol-3-phosphatedehydrogenase, paralogous to T25G3.4 and orthologous to human GPD2(OMIM:138430, mutated in type II diabetes mellitus); Y50E8A.6 has noobvious function in mass RNAi assays.Paper_evidenceWBPaper00026721
Curator_confirmedWBPerson567
Date_last_updated09 Apr 2007 00:00:00
Automated_descriptionPredicted to enable glycerol-3-phosphate dehydrogenase (quinone) activity. Predicted to be involved in glycerol-3-phosphate metabolic process and glycerophosphate shuttle. Predicted to be located in mitochondrion. Human ortholog(s) of this gene implicated in type 2 diabetes mellitus. Is an ortholog of human GPD2 (glycerol-3-phosphate dehydrogenase 2).Paper_evidenceWBPaper00065943
WBPaper00067038
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS296 version of WormBase
Date_last_updated20 Mar 2025 00:00:00
Disease_infoPotential_modelDOID:9352Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:4456)
Molecular_infoCorresponding_CDSY50E8A.6
Corresponding_CDS_historyY50E8A.6:wp156
Corresponding_transcriptY50E8A.6.1
Other_sequenceFG351947.1
Associated_featureWBsf1002119
WBsf1002120
WBsf1002121
WBsf1002122
WBsf1020908
WBsf1020909
Experimental_infoRNAi_resultWBRNAi00020841Inferred_automaticallyRNAi_primary
WBRNAi00057106Inferred_automaticallyRNAi_primary
Expr_patternExpr1011007
Expr1035801
Expr1160553
Expr2007764
Expr2026007
Microarray_results (18)
Expression_cluster (84)
Interaction (15)
Map_infoPositivePositive_cloneY50E8AInferred_automaticallyFrom sequence, transcript, pseudogene data
Interpolated_map_positionV6.75664
ReferenceWBPaper00038491
WBPaper00042257
MethodGene