WormBase Tree Display for Gene: WBGene00012148
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WBGene00012148 | SMap | S_parent | Sequence | CHROMOSOME_II | |||||
---|---|---|---|---|---|---|---|---|---|
Identity | Version | 2 | |||||||
Name | CGC_name | inos-1 | Person_evidence | WBPerson9275 | |||||
Sequence_name | VF13D12L.1 | ||||||||
Molecular_name | VF13D12L.1 | ||||||||
VF13D12L.1.1 | |||||||||
CE31076 | |||||||||
Other_name | CELE_VF13D12L.1 | Accession_evidence | NDB | BX284602 | |||||
Public_name | inos-1 | ||||||||
DB_info | Database (12) | ||||||||
Species | Caenorhabditis elegans | ||||||||
History | Version_change | 1 | 26 May 2004 16:54:53 | WBPerson1971 | Event | Imported | Initial conversion from CDS class of WS125 | ||
2 | 05 May 2011 12:15:34 | WBPerson2970 | Name_change | CGC_name | inos-1 | ||||
Status | Live | ||||||||
Gene_info | Biotype | SO:0001217 | |||||||
Gene_class | inos | ||||||||
Allele (39) | |||||||||
RNASeq_FPKM (74) | |||||||||
GO_annotation (11) | |||||||||
Ortholog (36) | |||||||||
Structured_description | Concise_description | inos-1 encodes the C. elegans myo-inositol-1-phosphate (MIP) synthase ortholog; by homology, the product of inos-1 is predicted to function in de novo inositol biosynthesis by catalyzing the conversion of glucose-6-phosphate to inositol-1-phosphate; loss of inos-1 activity via RNAi has been reported to result in low levels of embryonic lethality, larval lethality, slow growth, uncoordinated locomotion, and a substantial increase in fat content; loss of inos-1 activity also results in a slight increase in the variability of the defecation cycle length, although this increase is not statistically significant; in situ hybridization studies reveal that inos-1 mRNA is expressed faintly in the germline. | Paper_evidence | WBPaper00005654 | |||||
WBPaper00005655 | |||||||||
WBPaper00006395 | |||||||||
WBPaper00025054 | |||||||||
WBPaper00027758 | |||||||||
WBPaper00031535 | |||||||||
Curator_confirmed | WBPerson1843 | ||||||||
Date_last_updated | 05 May 2011 00:00:00 | ||||||||
Automated_description | Predicted to enable inositol-3-phosphate synthase activity. Predicted to be involved in inositol biosynthetic process. Predicted to be located in cytoplasm. Expressed in germ line. Is an ortholog of human ISYNA1 (inositol-3-phosphate synthase 1). | Paper_evidence | WBPaper00065943 | ||||||
Curator_confirmed | WBPerson324 | ||||||||
WBPerson37462 | |||||||||
Inferred_automatically | This description was generated automatically by a script based on data from the WS292 version of WormBase | ||||||||
Date_last_updated | 24 Apr 2024 00:00:00 | ||||||||
Molecular_info | Corresponding_CDS | VF13D12L.1 | |||||||
Corresponding_transcript | VF13D12L.1.1 | ||||||||
Other_sequence (81) | |||||||||
Associated_feature | WBsf650614 | ||||||||
WBsf650615 | |||||||||
WBsf650616 | |||||||||
WBsf666190 | |||||||||
WBsf666191 | |||||||||
WBsf989857 | |||||||||
WBsf223984 | |||||||||
Experimental_info | RNAi_result | WBRNAi00009234 | Inferred_automatically | RNAi_primary | |||||
WBRNAi00024196 | Inferred_automatically | RNAi_primary | |||||||
WBRNAi00033587 | Inferred_automatically | RNAi_primary | |||||||
WBRNAi00076726 | Inferred_automatically | RNAi_primary | |||||||
WBRNAi00026432 | Inferred_automatically | RNAi_primary | |||||||
WBRNAi00054466 | Inferred_automatically | RNAi_primary | |||||||
WBRNAi00054465 | Inferred_automatically | RNAi_primary | |||||||
WBRNAi00077806 | Inferred_automatically | RNAi_primary | |||||||
Expr_pattern | Expr4091 | ||||||||
Expr1023077 | |||||||||
Expr1035373 | |||||||||
Expr1158012 | |||||||||
Expr2012744 | |||||||||
Expr2030981 | |||||||||
Drives_construct | WBCnstr00030104 | ||||||||
Construct_product | WBCnstr00030104 | ||||||||
Microarray_results (19) | |||||||||
Expression_cluster (149) | |||||||||
Interaction (76) | |||||||||
Map_info | Map | II | Position | 3.99091 | Error | 0.005099 | |||
Positive | Positive_clone | VF13D12L | Inferred_automatically | From sequence, transcript, pseudogene data | |||||
Pseudo_map_position | |||||||||
Reference | WBPaper00019539 | ||||||||
WBPaper00031535 | |||||||||
WBPaper00038491 | |||||||||
WBPaper00055090 | |||||||||
Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||||
Method | Gene |