WormBase Tree Display for Gene: WBGene00011232
expand all nodes | collapse all nodes | view schema
WBGene00011232 | SMap | S_parent | Sequence | R11A5 | |||||
---|---|---|---|---|---|---|---|---|---|
Identity | Version | 2 | |||||||
Name | CGC_name | pck-2 | Person_evidence | WBPerson2192 | |||||
Sequence_name | R11A5.4 | ||||||||
Molecular_name (13) | |||||||||
Other_name | CELE_R11A5.4 | Accession_evidence | NDB | BX284601 | |||||
Public_name | pck-2 | ||||||||
DB_info | Database (12) | ||||||||
Species | Caenorhabditis elegans | ||||||||
History | Version_change | 1 | 26 May 2004 16:54:52 | WBPerson1971 | Event | Imported | Initial conversion from CDS class of WS125 | ||
2 | 17 Feb 2012 16:57:01 | WBPerson2970 | Name_change | CGC_name | pck-2 | ||||
Status | Live | ||||||||
Gene_info | Biotype | SO:0001217 | |||||||
Gene_class | pck | ||||||||
Allele (66) | |||||||||
Possibly_affected_by | WBVar02153165 | ||||||||
Strain | WBStrain00002263 | ||||||||
WBStrain00032650 | |||||||||
WBStrain00049322 | |||||||||
RNASeq_FPKM (74) | |||||||||
GO_annotation (20) | |||||||||
Ortholog (45) | |||||||||
Paralog | WBGene00021043 | Caenorhabditis elegans | From_analysis | Panther | |||||
WormBase-Compara | |||||||||
WBGene00019151 | Caenorhabditis elegans | From_analysis | Panther | ||||||
WormBase-Compara | |||||||||
Structured_description | Concise_description | pck-2 is one of three C. elegans genes that encode proteins with similarity to phosphoenolpyruvate carboxykinase (PEPCK); by similarity, the products of pck-2 are predicted to function in gluconeogenesis. | Curator_confirmed | WBPerson1843 | |||||
Date_last_updated | 02 Aug 2011 00:00:00 | ||||||||
Automated_description | Predicted to enable manganese ion binding activity and phosphoenolpyruvate carboxykinase (GTP) activity. Predicted to be involved in several processes, including carbohydrate biosynthetic process; cellular response to oxygen-containing compound; and propionate catabolic process. Predicted to be located in cytosol and mitochondrion. Expressed in several structures, including body wall musculature; hypodermis; muscle cell; pharynx; and in male. Human ortholog(s) of this gene implicated in Alzheimer's disease and type 2 diabetes mellitus. Is an ortholog of human PCK1 (phosphoenolpyruvate carboxykinase 1). | Paper_evidence | WBPaper00065943 | ||||||
Curator_confirmed | WBPerson324 | ||||||||
WBPerson37462 | |||||||||
Inferred_automatically | This description was generated automatically by a script based on data from the WS292 version of WormBase | ||||||||
Date_last_updated | 24 Apr 2024 00:00:00 | ||||||||
Disease_info | Potential_model | DOID:10652 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:8724) | ||||
DOID:9352 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:8724) | ||||||
Molecular_info | Corresponding_CDS | R11A5.4a | |||||||
R11A5.4b | |||||||||
R11A5.4c | |||||||||
R11A5.4d | |||||||||
Corresponding_CDS_history | R11A5.4b:wp274 | ||||||||
Corresponding_transcript | R11A5.4a.1 | ||||||||
R11A5.4a.2 | |||||||||
R11A5.4b.1 | |||||||||
R11A5.4c.1 | |||||||||
R11A5.4d.1 | |||||||||
Other_sequence (359) | |||||||||
Associated_feature (19) | |||||||||
Experimental_info | RNAi_result | WBRNAi00116976 | Inferred_automatically | RNAi_primary | |||||
WBRNAi00051760 | Inferred_automatically | RNAi_primary | |||||||
WBRNAi00077181 | Inferred_automatically | RNAi_primary | |||||||
WBRNAi00090555 | Inferred_automatically | RNAi_primary | |||||||
WBRNAi00034849 | Inferred_automatically | RNAi_primary | |||||||
WBRNAi00001222 | Inferred_automatically | RNAi_primary | |||||||
WBRNAi00051759 | Inferred_automatically | RNAi_primary | |||||||
WBRNAi00004079 | Inferred_automatically | RNAi_primary | |||||||
Expr_pattern (16) | |||||||||
Drives_construct | WBCnstr00002285 | ||||||||
WBCnstr00004292 | |||||||||
WBCnstr00004926 | |||||||||
WBCnstr00011844 | |||||||||
WBCnstr00030823 | |||||||||
WBCnstr00042040 | |||||||||
WBCnstr00042041 | |||||||||
Construct_product | WBCnstr00030823 | ||||||||
WBCnstr00042040 | |||||||||
Microarray_results (41) | |||||||||
Expression_cluster (250) | |||||||||
Interaction (47) | |||||||||
Map_info | Map | I | Position | 2.38327 | |||||
Positive | Positive_clone | R11A5 | Inferred_automatically | From sequence, transcript, pseudogene data | |||||
Pseudo_map_position | |||||||||
Reference (22) | |||||||||
Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||||
[200811 gw3] Modified Map position as it was a reverse physical that could not be fixed by automated methods. (2.36373) | |||||||||
Method | Gene |