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WormBase Tree Display for Gene: WBGene00010663

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Name Class

WBGene00010663SMapS_parentSequenceK08E3
IdentityVersion3
NameCGC_nametoca-2Person_evidenceWBPerson5000
WBPerson5001
Sequence_nameK08E3.3
Molecular_nameK08E3.3a
K08E3.3a.1
CE37123
K08E3.3b
CE37124
K08E3.3b.1
Other_nameCELE_K08E3.3Accession_evidenceNDBBX284603
Public_nametoca-2
DB_infoDatabase (11)
SpeciesCaenorhabditis elegans
HistoryVersion_change126 May 2004 16:54:51WBPerson1971EventImportedInitial conversion from CDS class of WS125
222 Jul 2004 11:40:09WBPerson1983EventSplit_intoWBGene00023451
331 May 2006 17:04:33WBPerson2970Name_changeCGC_nametoca-2
Split_intoWBGene00023451
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classtoca
Allele (53)
RNASeq_FPKM (74)
GO_annotation (28)
Ortholog (39)
ParalogWBGene00017298Caenorhabditis elegansFrom_analysisTreeFam
WormBase-Compara
Structured_descriptionAutomated_descriptionInvolved in several processes, including negative regulation of protein localization to adherens junction; positive regulation of egg-laying behavior; and regulation of cellular component organization. Located in several cellular components, including cell-cell junction; intracellular vesicle; and plasma membrane. Expressed in spermatheca and uterus. Human ortholog(s) of this gene implicated in Huntington's disease. Is an ortholog of human FNBP1 (formin binding protein 1); FNBP1L (formin binding protein 1 like); and TRIP10 (thyroid hormone receptor interactor 10).Paper_evidenceWBPaper00065943
WBPaper00067038
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS296 version of WormBase
Date_last_updated20 Mar 2025 00:00:00
Disease_infoPotential_modelDOID:12858Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:12304)
Molecular_infoCorresponding_CDSK08E3.3a
K08E3.3b
Corresponding_CDS_historyK08E3.3a:wp129
K08E3.3b:wp129
Corresponding_transcriptK08E3.3a.1
K08E3.3b.1
Other_sequenceCRC06437_1
DI02200
HBC16197_1
DIC01573_1
CR07394
EX014135.1
Associated_featureWBsf645733
WBsf659780
WBsf995013
WBsf226063
Experimental_infoRNAi_resultWBRNAi00016806Inferred_automaticallyRNAi_primary
WBRNAi00050283Inferred_automaticallyRNAi_primary
WBRNAi00006275Inferred_automaticallyRNAi_primary
Expr_patternExpr2133
Expr8794
Expr8796
Expr12308
Expr1024110
Expr1034661
Expr1153985
Expr2017440
Expr2035579
Drives_constructWBCnstr00031243
Construct_productWBCnstr00013530
WBCnstr00020634
WBCnstr00031243
AntibodyWBAntibody00001521
WBAntibody00001983
Microarray_results (31)
Expression_cluster (139)
Interaction (39)
Map_infoMapIIIPosition21.4902Error0.008637
PositivePositive_cloneK08E3Inferred_automaticallyFrom sequence, transcript, pseudogene data
Pseudo_map_position
ReferenceWBPaper00006090
WBPaper00035252
WBPaper00038491
WBPaper00039213
WBPaper00043728
WBPaper00046549
WBPaper00048254
WBPaper00048842
WBPaper00055090
RemarkMap position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.CGC_data_submission
MethodGene