WormBase Tree Display for Gene: WBGene00007631

WBGene00007631 SMap: S_parent: Sequence: C16C10
  Identity: Version: 2
    Name: CGC_name: wht-3 Person_evidence: WBPerson253
      Sequence_name: C16C10.12
      Molecular_name (12)
      Other_name: CELE_C16C10.12 Accession_evidence: NDB BX284603
      Public_name: wht-3
    DB_info: Database: AceView gene 3F238
        WormQTL gene WBGene00007631
        WormFlux gene WBGene00007631
        NDB locus_tag CELE_C16C10.12
        Panther gene CAEEL|WormBase=WBGene00007631|UniProtKB=Q09466
          family PTHR48041
        NCBI gene 175528
        RefSeq protein NM_001322781.3
            NM_065424.3
            NM_001322780.3
            NM_001322779.3
        SwissProt UniProtAcc Q09466
        TrEMBL UniProtAcc A0A131MCE2
            A0A131MAX2
            A0A131MBH6
        UniProt_GCRP UniProtAcc Q09466
    Species: Caenorhabditis elegans
    History: Version_change: 1 26 May 2004 16:54:48 WBPerson1971 Event: Imported: Initial conversion from CDS class of WS125
        2 04 Jun 2007 15:54:19 WBPerson2970 Name_change: CGC_name: wht-3
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: wht
    Allele (58)
    Strain: WBStrain00031716
      WBStrain00031741
    RNASeq_FPKM (74)
    GO_annotation (12)
    Ortholog (32)
    Paralog: WBGene00006522 Caenorhabditis elegans From_analysis: Panther
            WormBase-Compara
      WBGene00007060 Caenorhabditis elegans From_analysis: TreeFam
            Panther
            WormBase-Compara
      WBGene00007513 Caenorhabditis elegans From_analysis: Panther
            WormBase-Compara
      WBGene00012925 Caenorhabditis elegans From_analysis: TreeFam
            Panther
            WormBase-Compara
      WBGene00017179 Caenorhabditis elegans From_analysis: TreeFam
            Panther
            WormBase-Compara
      WBGene00008950 Caenorhabditis elegans From_analysis: TreeFam
            Panther
            WormBase-Compara
      WBGene00015479 Caenorhabditis elegans From_analysis: TreeFam
            Panther
            WormBase-Compara
      WBGene00021535 Caenorhabditis elegans From_analysis: TreeFam
            Panther
            WormBase-Compara
      WBGene00016973 Caenorhabditis elegans From_analysis: Panther
            WormBase-Compara
    Structured_description: Concise_description: wht-3 encodes an ATP-binding cassette (ABC) transporter; wht-3 activity is required for efficient RNA interference (RNAi) of a germline-expressed target, pop-1, as well as for normal pharyngeal and body morphology. Paper_evidence: WBPaper00027644
            WBPaper00040399
          Curator_confirmed: WBPerson1843
          Date_last_updated: 16 Nov 2011 00:00:00
      Automated_description: Predicted to enable ATPase-coupled transmembrane transporter activity. Predicted to be involved in transmembrane transport. Predicted to be located in plasma membrane. Human ortholog(s) of this gene implicated in several diseases, including gout; hematologic cancer (multiple); and toxic encephalopathy. Is an ortholog of human ABCG2 (ATP binding cassette subfamily G member 2 (JR blood group)). Paper_evidence: WBPaper00065943
            WBPaper00067038
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS296 version of WormBase
          Date_last_updated: 20 Mar 2025 00:00:00
  Molecular_info: Corresponding_CDS: C16C10.12a
      C16C10.12b
      C16C10.12c
      C16C10.12d
    Corresponding_CDS_history: C16C10.12:wp252
    Corresponding_transcript: C16C10.12a.1
      C16C10.12b.1
      C16C10.12c.1
      C16C10.12d.1
    Associated_feature: WBsf981449
      WBsf992045
      WBsf226471
  Experimental_info: RNAi_result: WBRNAi00040676 Inferred_automatically: RNAi_primary
      WBRNAi00040675 Inferred_automatically: RNAi_primary
      WBRNAi00007062 Inferred_automatically: RNAi_primary
      WBRNAi00005051 Inferred_automatically: RNAi_primary
      WBRNAi00102075 Inferred_automatically: RNAi_primary
      WBRNAi00028953 Inferred_automatically: RNAi_primary
      WBRNAi00072937 Inferred_automatically: RNAi_primary
      WBRNAi00010827 Inferred_automatically: RNAi_primary
      WBRNAi00001808 Inferred_automatically: RNAi_primary
    Expr_pattern: Expr1023683
      Expr1144722
      Expr2018064
      Expr2036201
    Drives_construct: WBCnstr00033592
    Construct_product: WBCnstr00033592
    Microarray_results (18)
    Expression_cluster (134)
    Interaction (68)
  Map_info: Map: III Position: -3.78278 Error: 0.001298
    Positive: Positive_clone: C16C10 Inferred_automatically: From sequence, transcript, pseudogene data
    Pseudo_map_position
  Reference: WBPaper00027644
    WBPaper00031484
    WBPaper00038491
    WBPaper00040399
    WBPaper00055090
  Remark: Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. CGC_data_submission
  Method: Gene