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WormBase Tree Display for Gene: WBGene00007258

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Name Class

WBGene00007258SMapS_parentSequenceCHROMOSOME_I
IdentityVersion2
NameCGC_namehasp-1Person_evidenceWBPerson260
Sequence_nameC01H6.9
Molecular_nameC01H6.9
C01H6.9.1
CE42869
Other_nameCELE_C01H6.9Accession_evidenceNDBBX284601
Public_namehasp-1
DB_infoDatabase (12)
SpeciesCaenorhabditis elegans
HistoryVersion_change126 May 2004 16:54:47WBPerson1971EventImportedInitial conversion from CDS class of WS125
209 Dec 2014 15:51:18WBPerson2970Name_changeCGC_namehasp-1
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classhasp
Allele (36)
RNASeq_FPKM (74)
GO_annotation (18)
Contained_in_operonCEOP1376
Ortholog (46)
Paralog (12)
Structured_descriptionConcise_descriptionhasp-1 encodes a homolog of vertebrate haploid germ cell-specific nuclear protein kinase (haspin); the hasp-1 tm3858 deletion mutation has been classified as lethal or sterile by the National Bioresource Project of Japan; HASP-1 specifically binds GOA-1 in yeast two-hybrid assays; HASP-1 is expressed in PHB sensory neurons and PVT interneurons in the tail, several unidentified neurons in the head (with projections to the nose and nerve ring), and intestinal cells; HASP-1 is paralogous to HASP-2, encoded by Y18H1A.10; in addition, there are two pseudogenes, F22H10.5 and Y40A1A.1, in the C. elegans genome that share sequence similarity to HASP-1 and HASP-2.Paper_evidenceWBPaper00006194
Curator_confirmedWBPerson1843
WBPerson567
Date_last_updated19 Dec 2014 00:00:00
Automated_descriptionEnables G-protein alpha-subunit binding activity and histone H3T3 kinase activity. Predicted to be involved in intracellular signal transduction and mitotic cell cycle. Predicted to be located in cytoplasm and nucleus. Expressed in PHB; PVT; head neurons; intestine; and seam cell. Is an ortholog of human HASPIN (histone H3 associated protein kinase).Paper_evidenceWBPaper00065943
WBPaper00067038
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS296 version of WormBase
Date_last_updated20 Mar 2025 00:00:00
Molecular_infoCorresponding_CDSC01H6.9
Corresponding_CDS_historyC01H6.9:wp192
C01H6.9:wp193
Corresponding_transcriptC01H6.9.1
Other_sequenceXIC03618_1
CRC04477_1
CR04112
XI02862
Associated_featureWBsf649297
WBsf664423
WBsf219706
WBsf219707
WBsf219708
WBsf219709
Experimental_infoRNAi_resultWBRNAi00063374Inferred_automaticallyRNAi_primary
WBRNAi00063373Inferred_automaticallyRNAi_primary
WBRNAi00063362Inferred_automaticallyRNAi_primary
WBRNAi00116590Inferred_automaticallyRNAi_primary
WBRNAi00028323Inferred_automaticallyRNAi_primary
WBRNAi00063361Inferred_automaticallyRNAi_primary
WBRNAi00062104Inferred_automaticallyRNAi_primary
WBRNAi00009956Inferred_automaticallyRNAi_primary
WBRNAi00039377Inferred_automaticallyRNAi_primary
Expr_patternExpr2751
Expr1014423
Expr1033131
Expr1143492
Expr2012371
Expr2030607
Drives_constructWBCnstr00010931
WBCnstr00033879
Construct_productWBCnstr00010931
WBCnstr00021071
WBCnstr00021072
WBCnstr00033879
Microarray_results (19)
Expression_cluster (150)
InteractionWBInteraction000031975
WBInteraction000542827
WBInteraction000582146
Map_infoMapIPosition1.85027
PositivePositive_cloneC01H6Inferred_automaticallyFrom sequence, transcript, pseudogene data
Pseudo_map_position
ReferenceWBPaper00027258
WBPaper00038491
WBPaper00051993
WBPaper00055090
WBPaper00057802
WBPaper00063132
WBPaper00064160
WBPaper00064339
RemarkMap position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.CGC_data_submission
MethodGene