WormBase Tree Display for Gene: WBGene00006743
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WBGene00006743 | SMap | S_parent | Sequence | CHROMOSOME_X | |||||
---|---|---|---|---|---|---|---|---|---|
Identity | Version | 1 | |||||||
Name (5) | |||||||||
DB_info | Database (11) | ||||||||
Species | Caenorhabditis elegans | ||||||||
History | Version_change | 1 | 07 Apr 2004 11:29:41 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
Status | Live | ||||||||
Gene_info | Biotype | SO:0001217 | |||||||
Gene_class | unc | ||||||||
Reference_allele | WBVar00142996 | ||||||||
Allele (232) | |||||||||
Legacy_information | e151 : weak coiler tends to coil tail active; very disorganized ventral nerve cord; mutant focus in ABp descendants; ES3 ME1. Similar phenotype in e151/Df. NA4 (e54 (weaker allele) e95 etc.). | ||||||||
[C.elegansII] e151 : weak coiler tends to coil, tail active, good head movement; very disorganized ventral nerve cord; mosaic analysis indicates mutant focus in ventral cord motor neurons. Similar phenotype ine151/Df. ES3 ME1.OA>5: e54 (weaker allele), e95, mn419, p1001 etc. Cloned: polymorphisms identified in mn419 and derivatives (cosmid F42D1). [Brenner 1974; Herman and Kari 1987; NG; SP] | |||||||||
Strain (93) | |||||||||
RNASeq_FPKM (74) | |||||||||
GO_annotation (27) | |||||||||
Ortholog (47) | |||||||||
Structured_description | Automated_description | Enables RNA polymerase II transcription regulatory region sequence-specific DNA binding activity; histone acetyltransferase binding activity; and identical protein binding activity. Involved in several processes, including dauer larval development; neuron differentiation; and positive regulation of transcription by RNA polymerase II. Located in nucleus. Expressed in ABalappaap; ABalappaapp; and neurons. Human ortholog(s) of this gene implicated in hypotonia, ataxia, and delayed development syndrome. Is an ortholog of several human genes including EBF1 (EBF transcription factor 1); EBF2 (EBF transcription factor 2); and EBF4 (EBF family member 4). | Paper_evidence | WBPaper00065943 | |||||
Curator_confirmed | WBPerson324 | ||||||||
WBPerson37462 | |||||||||
Inferred_automatically | This description was generated automatically by a script based on data from the WS292 version of WormBase | ||||||||
Date_last_updated | 24 Apr 2024 00:00:00 | ||||||||
Disease_info | Potential_model | DOID:0081176 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:19087) | ||||
Molecular_info | Corresponding_CDS | Y16B4A.1 | |||||||
Corresponding_CDS_history | Y16B4A.1:wp62 | ||||||||
Corresponding_transcript | Y16B4A.1.1 | ||||||||
Other_sequence (23) | |||||||||
Associated_feature (19) | |||||||||
Transcription_factor | WBTranscriptionFactor000217 | ||||||||
Experimental_info | RNAi_result | WBRNAi00115872 | Inferred_automatically | RNAi_primary | |||||
WBRNAi00090173 | Inferred_automatically | RNAi_primary | |||||||
WBRNAi00090014 | Inferred_automatically | RNAi_primary | |||||||
WBRNAi00027739 | Inferred_automatically | RNAi_primary | |||||||
WBRNAi00020068 | Inferred_automatically | RNAi_primary | |||||||
WBRNAi00055554 | Inferred_automatically | RNAi_primary | |||||||
WBRNAi00062789 | Inferred_automatically | RNAi_primary | |||||||
WBRNAi00008787 | Inferred_automatically | RNAi_primary | |||||||
WBRNAi00090332 | Inferred_automatically | RNAi_primary | |||||||
WBRNAi00089778 | Inferred_automatically | RNAi_primary | |||||||
Expr_pattern (13) | |||||||||
Drives_construct (11) | |||||||||
Construct_product (14) | |||||||||
Antibody | WBAntibody00000177 | ||||||||
Microarray_results (21) | |||||||||
Expression_cluster (189) | |||||||||
Interaction (195) | |||||||||
Map_info | Map | X | Position | 21.3208 | Error | 0.014822 | |||
Well_ordered | |||||||||
Positive | Positive_clone | F42D1 | |||||||
Y16B4A | Inferred_automatically | From sequence, transcript, pseudogene data | |||||||
Negative | Negative_clone | K01B4 | |||||||
Mapping_data | 2_point (52) | ||||||||
Multi_point (53) | |||||||||
Pos_neg_data (39) | |||||||||
Landmark_gene | |||||||||
Reference (217) | |||||||||
Remark | [Eddy SR] EcoRV RFLP correlated with unc-3. 3.8 kb EcoRV band in N2, 2.3 kb in unc-3 (mn419), 3.8 kb again in revertants unc-3 (mn419 mn422) and unc-3 (mn419 mn426), 3.7 kb in revertant unc-3 (mn419 mn431). | ||||||||
Polymorphism detection method = Southern hybridisation krb 04/03/02 | |||||||||
Method | Gene |