WormBase Tree Display for Gene: WBGene00006510
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| WBGene00006510 | SMap | S_parent | Sequence | C01G6 | |||||
|---|---|---|---|---|---|---|---|---|---|
| Identity | Version | 2 | |||||||
| Name | CGC_name | mtrr-1 | Person_evidence | WBPerson1711 | |||||
| Sequence_name | C01G6.6 | ||||||||
| Molecular_name | C01G6.6a | ||||||||
| C01G6.6a.1 | |||||||||
| CE00868 | |||||||||
| C01G6.6b | |||||||||
| Other_name | tag-165 | ||||||||
| CELE_C01G6.6 | Accession_evidence | NDB | BX284602 | ||||||
| Public_name | mtrr-1 | ||||||||
| DB_info | Database (14) | ||||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 07 Apr 2004 11:29:40 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
| 2 | 20 Apr 2011 10:05:24 | WBPerson2970 | Name_change | CGC_name | mtrr-1 | ||||
| Other_name | tag-165 | ||||||||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | mtrr | ||||||||
| Allele (49) | |||||||||
| Strain | WBStrain00035852 | ||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation (13) | |||||||||
| Ortholog (37) | |||||||||
| Paralog | WBGene00001262 | Caenorhabditis elegans | From_analysis | Panther | |||||
| WormBase-Compara | |||||||||
| WBGene00001485 | Caenorhabditis elegans | From_analysis | Panther | ||||||
| WormBase-Compara | |||||||||
| WBGene00021314 | Caenorhabditis elegans | From_analysis | WormBase-Compara | ||||||
| Structured_description | Concise_description | C01G6.6 encodes an ortholog of the human gene METHIONINE SYNTHASE REDUCTASE (MTRR), which when mutated leads to homocystinuria (OMIM:236270) | Paper_evidence | WBPaper00004637 | |||||
| Curator_confirmed | WBPerson1823 | ||||||||
| WBPerson567 | |||||||||
| Date_last_updated | 09 Aug 2004 00:00:00 | ||||||||
| Automated_description | Predicted to enable FMN binding activity; [methionine synthase] reductase (NADPH) activity; and flavin adenine dinucleotide binding activity. Predicted to be involved in homocysteine metabolic process and methionine biosynthetic process. Predicted to be located in cytosol. Human ortholog(s) of this gene implicated in several diseases, including abdominal aortic aneurysm; endocrine gland cancer (multiple); and hematologic cancer (multiple). Is an ortholog of human MTRR (5-methyltetrahydrofolate-homocysteine methyltransferase reductase). | Paper_evidence | WBPaper00065943 | ||||||
| WBPaper00067038 | |||||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS296 version of WormBase | ||||||||
| Date_last_updated | 20 Mar 2025 00:00:00 | ||||||||
| Disease_info | Potential_model (17) | ||||||||
| Molecular_info | Corresponding_CDS | C01G6.6a | |||||||
| Corresponding_CDS_history | C01G6.6b:wp252 | ||||||||
| Corresponding_transcript | C01G6.6b | ||||||||
| C01G6.6a.1 | |||||||||
| Other_sequence (33) | |||||||||
| Associated_feature (11) | |||||||||
| Experimental_info | RNAi_result | WBRNAi00039357 | Inferred_automatically | RNAi_primary | |||||
| WBRNAi00028306 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00009953 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00062102 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00107057 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00107059 | Inferred_automatically | RNAi_primary | |||||||
| Expr_pattern | Expr1020855 | ||||||||
| Expr1032666 | |||||||||
| Expr1143473 | |||||||||
| Expr2013817 | |||||||||
| Expr2032057 | |||||||||
| Drives_construct | WBCnstr00037892 | ||||||||
| Construct_product | WBCnstr00037892 | ||||||||
| Microarray_results (35) | |||||||||
| Expression_cluster (178) | |||||||||
| Interaction (46) | |||||||||
| Map_info | Map | II | Position | 1.0987 | Error | 0.000654 | |||
| Positive | Positive_clone | C01G6 | Inferred_automatically | From sequence, transcript, pseudogene data | |||||
| Pseudo_map_position | |||||||||
| Reference | WBPaper00028527 | ||||||||
| WBPaper00038491 | |||||||||
| WBPaper00049828 | |||||||||
| WBPaper00049923 | |||||||||
| WBPaper00055090 | |||||||||
| WBPaper00060431 | |||||||||
| WBPaper00064989 | |||||||||
| WBPaper00065026 | |||||||||
| WBPaper00066161 | |||||||||
| WBPaper00066805 | |||||||||
| Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||||
| Method | Gene |
