WormBase Tree Display for Gene: WBGene00004350
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WBGene00004350 | SMap | S_parent | Sequence | F56B6 | |||
---|---|---|---|---|---|---|---|
Identity | Version | 2 | |||||
Name | CGC_name | rgs-7 | Person_evidence | WBPerson330 | |||
Sequence_name | F56B6.2 | ||||||
Molecular_name (27) | |||||||
Other_name | CELE_F56B6.2 | Accession_evidence | NDB | BX284606 | |||
Public_name | rgs-7 | ||||||
DB_info | Database | AceView | gene | XE175 | |||
WormQTL | gene | WBGene00004350 | |||||
WormFlux | gene | WBGene00004350 | |||||
NDB | locus_tag | CELE_F56B6.2 | |||||
Panther | gene | CAEEL|WormBase=WBGene00004350|UniProtKB=Q8WQC0 | |||||
family | PTHR10845 | ||||||
NCBI | gene | 180645 | |||||
RefSeq | protein | NM_001129682.5 | |||||
NM_001373262.3 | |||||||
NM_001373261.4 | |||||||
NM_001374994.1 | |||||||
NM_001029543.5 | |||||||
NM_001129681.4 | |||||||
NM_001373260.4 | |||||||
NM_001029544.6 | |||||||
NM_076209.7 | |||||||
SwissProt | UniProtAcc | Q8WQC0 | |||||
TrEMBL | UniProtAcc | A0A4V0IJG9 | |||||
Q1W0R0 | |||||||
H2KYQ7 | |||||||
A0A4V0IKM4 | |||||||
A0A4V0ILX5 | |||||||
H2KYQ8 | |||||||
UniProt_GCRP | UniProtAcc | Q8WQC0 | |||||
Species | Caenorhabditis elegans | ||||||
History | Version_change (2) | ||||||
Acquires_merge | WBGene00018936 | ||||||
Status | Live | ||||||
Gene_info | Biotype | SO:0001217 | |||||
Gene_class | rgs | ||||||
Allele (194) | |||||||
Strain | WBStrain00026370 | ||||||
WBStrain00026372 | |||||||
WBStrain00032622 | |||||||
WBStrain00034758 | |||||||
RNASeq_FPKM (74) | |||||||
GO_annotation | 00003513 | ||||||
00020704 | |||||||
00020705 | |||||||
00020706 | |||||||
00080909 | |||||||
Ortholog (38) | |||||||
Paralog (12) | |||||||
Structured_description | Concise_description | rgs-7 encodes three isoforms of an atypical regulator of G protein signaling (RGS) protein that contains both a C2 and an RGS domain, and that binds EGL-30 via both domains, similar in organization to mammalian PDZ-RGS3; the RGS domain has GTPase activator protein (GAP) activity in vitro on mammalian G[alphai]3; RGS-7 thus may stably bind EGL-30 at all stages of EGL-30's GTPase cycle, might organize EGL-30 into a stable multiprotein signalling complex (with GTP[gamma]S), and might persistently inhibit EGL-30 when triggered by calcium or phospholipids; rgs-7 has no obvious function in mass RNAi assays | Paper_evidence | WBPaper00005654 | |||
WBPaper00005958 | |||||||
WBPaper00013066 | |||||||
Curator_confirmed | WBPerson567 | ||||||
Date_last_updated | 18 Jun 2007 00:00:00 | ||||||
Automated_description | Enables GTPase activator activity. Predicted to be involved in negative regulation of signal transduction. Located in cell cortex. Is an ortholog of several human genes including RGS1 (regulator of G protein signaling 1); RGS13 (regulator of G protein signaling 13); and RGS4 (regulator of G protein signaling 4). | Paper_evidence | WBPaper00065943 | ||||
Curator_confirmed | WBPerson324 | ||||||
WBPerson37462 | |||||||
Inferred_automatically | This description was generated automatically by a script based on data from the WS292 version of WormBase | ||||||
Date_last_updated | 24 Apr 2024 00:00:00 | ||||||
Molecular_info | Corresponding_CDS | F56B6.2a | |||||
F56B6.2b | |||||||
F56B6.2c | |||||||
F56B6.2e | |||||||
F56B6.2f | |||||||
F56B6.2g | |||||||
F56B6.2h | |||||||
F56B6.2i | |||||||
F56B6.2j | |||||||
Corresponding_CDS_history | F56B6.2d:wp271 | ||||||
Corresponding_transcript | F56B6.2a.1 | ||||||
F56B6.2b.1 | |||||||
F56B6.2c.1 | |||||||
F56B6.2e.1 | |||||||
F56B6.2f.1 | |||||||
F56B6.2g.1 | |||||||
F56B6.2h.1 | |||||||
F56B6.2i.1 | |||||||
F56B6.2j.1 | |||||||
Other_sequence (21) | |||||||
Associated_feature (27) | |||||||
Experimental_info | RNAi_result | WBRNAi00048645 | Inferred_automatically | RNAi_primary | |||
WBRNAi00048644 | Inferred_automatically | RNAi_primary | |||||
WBRNAi00032932 | Inferred_automatically | RNAi_primary | |||||
WBRNAi00015785 | Inferred_automatically | RNAi_primary | |||||
Expr_pattern | Expr3108 | ||||||
Expr1025711 | |||||||
Expr1032168 | |||||||
Expr1152407 | |||||||
Expr1200208 | |||||||
Expr2015330 | |||||||
Expr2033564 | |||||||
Drives_construct | WBCnstr00011142 | ||||||
WBCnstr00035547 | |||||||
Construct_product | WBCnstr00011142 | ||||||
WBCnstr00035547 | |||||||
Microarray_results (53) | |||||||
Expression_cluster (147) | |||||||
Interaction (11) | |||||||
WBProcess | WBbiopr:00000017 | ||||||
Map_info | Map | X | Position | -10.1117 | Error | 0.033929 | |
Positive | Positive_clone | F56B6 | Inferred_automatically | From sequence, transcript, pseudogene data | |||
Mapping_data | Multi_point | 5042 | |||||
Pseudo_map_position | |||||||
Reference (17) | |||||||
Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||
Method | Gene |