WormBase Tree Display for Gene: WBGene00004350
expand all nodes | collapse all nodes | view schema
WBGene00004350 | SMap | S_parent | Sequence | F56B6 | |||||
---|---|---|---|---|---|---|---|---|---|
Identity | Version | 2 | |||||||
Name | CGC_name | rgs-7 | Person_evidence | WBPerson330 | |||||
Sequence_name | F56B6.2 | ||||||||
Molecular_name (27) | |||||||||
Other_name | CELE_F56B6.2 | Accession_evidence | NDB | BX284606 | |||||
Public_name | rgs-7 | ||||||||
DB_info | Database (10) | ||||||||
Species | Caenorhabditis elegans | ||||||||
History | Version_change | 1 | 07 Apr 2004 11:29:35 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
2 | 03 Dec 2004 16:13:27 | WBPerson2970 | Event | Acquires_merge | WBGene00018936 | ||||
Acquires_merge | WBGene00018936 | ||||||||
Status | Live | ||||||||
Gene_info | Biotype | SO:0001217 | |||||||
Gene_class | rgs | ||||||||
Allele (194) | |||||||||
Strain | WBStrain00026370 | ||||||||
WBStrain00026372 | |||||||||
WBStrain00032622 | |||||||||
WBStrain00034758 | |||||||||
RNASeq_FPKM (74) | |||||||||
GO_annotation | 00003513 | ||||||||
00020704 | |||||||||
00020705 | |||||||||
00020706 | |||||||||
00080909 | |||||||||
Ortholog (38) | |||||||||
Paralog (12) | |||||||||
Structured_description | Concise_description | rgs-7 encodes three isoforms of an atypical regulator of G protein signaling (RGS) protein that contains both a C2 and an RGS domain, and that binds EGL-30 via both domains, similar in organization to mammalian PDZ-RGS3; the RGS domain has GTPase activator protein (GAP) activity in vitro on mammalian G[alphai]3; RGS-7 thus may stably bind EGL-30 at all stages of EGL-30's GTPase cycle, might organize EGL-30 into a stable multiprotein signalling complex (with GTP[gamma]S), and might persistently inhibit EGL-30 when triggered by calcium or phospholipids; rgs-7 has no obvious function in mass RNAi assays | Paper_evidence | WBPaper00005654 | |||||
WBPaper00005958 | |||||||||
WBPaper00013066 | |||||||||
Curator_confirmed | WBPerson567 | ||||||||
Date_last_updated | 18 Jun 2007 00:00:00 | ||||||||
Automated_description | Enables GTPase activator activity. Predicted to be involved in negative regulation of signal transduction. Located in cell cortex. Is an ortholog of several human genes including RGS1 (regulator of G protein signaling 1); RGS13 (regulator of G protein signaling 13); and RGS4 (regulator of G protein signaling 4). | Paper_evidence | WBPaper00065943 | ||||||
Curator_confirmed | WBPerson324 | ||||||||
WBPerson37462 | |||||||||
Inferred_automatically | This description was generated automatically by a script based on data from the WS292 version of WormBase | ||||||||
Date_last_updated | 24 Apr 2024 00:00:00 | ||||||||
Molecular_info | Corresponding_CDS | F56B6.2a | |||||||
F56B6.2b | |||||||||
F56B6.2c | |||||||||
F56B6.2e | |||||||||
F56B6.2f | |||||||||
F56B6.2g | |||||||||
F56B6.2h | |||||||||
F56B6.2i | |||||||||
F56B6.2j | |||||||||
Corresponding_CDS_history | F56B6.2d:wp271 | ||||||||
Corresponding_transcript | F56B6.2a.1 | ||||||||
F56B6.2b.1 | |||||||||
F56B6.2c.1 | |||||||||
F56B6.2e.1 | |||||||||
F56B6.2f.1 | |||||||||
F56B6.2g.1 | |||||||||
F56B6.2h.1 | |||||||||
F56B6.2i.1 | |||||||||
F56B6.2j.1 | |||||||||
Other_sequence (21) | |||||||||
Associated_feature (27) | |||||||||
Experimental_info | RNAi_result | WBRNAi00048645 | Inferred_automatically | RNAi_primary | |||||
WBRNAi00048644 | Inferred_automatically | RNAi_primary | |||||||
WBRNAi00032932 | Inferred_automatically | RNAi_primary | |||||||
WBRNAi00015785 | Inferred_automatically | RNAi_primary | |||||||
Expr_pattern | Expr3108 | ||||||||
Expr1025711 | |||||||||
Expr1032168 | |||||||||
Expr1152407 | |||||||||
Expr1200208 | |||||||||
Expr2015330 | |||||||||
Expr2033564 | |||||||||
Drives_construct | WBCnstr00011142 | ||||||||
WBCnstr00035547 | |||||||||
Construct_product | WBCnstr00011142 | ||||||||
WBCnstr00035547 | |||||||||
Microarray_results (53) | |||||||||
Expression_cluster (147) | |||||||||
Interaction (11) | |||||||||
WBProcess | WBbiopr:00000017 | ||||||||
Map_info | Map | X | Position | -10.1117 | Error | 0.033929 | |||
Positive | Positive_clone | F56B6 | Inferred_automatically | From sequence, transcript, pseudogene data | |||||
Mapping_data | Multi_point | 5042 | |||||||
Pseudo_map_position | |||||||||
Reference (17) | |||||||||
Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||||
Method | Gene |