WormBase Tree Display for Gene: WBGene00003504
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WBGene00003504 | Evidence | CGC_data_submission | |||||||
---|---|---|---|---|---|---|---|---|---|
SMap | S_parent | Sequence | ZK1098 | ||||||
Identity | Version | 1 | |||||||
Name | CGC_name | mut-7 | Person_evidence | WBPerson261 | |||||
Sequence_name | ZK1098.8 | ||||||||
Molecular_name | ZK1098.8 | ||||||||
ZK1098.8.1 | |||||||||
CE00370 | |||||||||
Other_name | CELE_ZK1098.8 | Accession_evidence | NDB | BX284603 | |||||
Public_name | mut-7 | ||||||||
DB_info | Database (12) | ||||||||
Species | Caenorhabditis elegans | ||||||||
History | Version_change | 1 | 07 Apr 2004 11:29:32 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
Status | Live | ||||||||
Gene_info | Biotype | SO:0001217 | |||||||
Gene_class | mut | ||||||||
Allele (47) | |||||||||
Strain | WBStrain00003332 | ||||||||
WBStrain00028942 | |||||||||
WBStrain00028975 | |||||||||
WBStrain00034635 | |||||||||
WBStrain00040468 | |||||||||
In_cluster | conserved_miRNA_siRNA_cluster | ||||||||
RNASeq_FPKM (74) | |||||||||
GO_annotation (22) | |||||||||
Ortholog (28) | |||||||||
Paralog | WBGene00014220 | Caenorhabditis elegans | From_analysis | TreeFam | |||||
Inparanoid_8 | |||||||||
Panther | |||||||||
WormBase-Compara | |||||||||
WBGene00013256 | Caenorhabditis elegans | From_analysis | TreeFam | ||||||
WBGene00012290 | Caenorhabditis elegans | From_analysis | Panther | ||||||
Structured_description | Concise_description | mut-7 encodes a homolog of RnaseD that represses transposition of Tc1, Tc3, Tc4, and Tc5, perhaps by degrading transposon-specific messages; also affects sperm development, sensitivity to RNAi of mainly germline expressed genes, silencing of some germline transgenes, X chromosome loss, and is required for cosuppression (functional silencing of chromosomal loci induced by transgenes) and for silencing induced by antisense RNA oligomers; cellular fractionation experiments indicate that MUT-7 is expressed in adult worms, and resides in a complex in both the cytosol and nucleus; in the cytosolic complex, MUT-7 interacts with RDE-2, a novel protein also required for RNA interference. | Paper_evidence | WBPaper00003711 | |||||
WBPaper00003722 | |||||||||
WBPaper00003956 | |||||||||
WBPaper00004198 | |||||||||
WBPaper00005077 | |||||||||
WBPaper00024699 | |||||||||
Curator_confirmed | WBPerson48 | ||||||||
WBPerson1843 | |||||||||
Date_last_updated | 28 Dec 2005 00:00:00 | ||||||||
Automated_description | Predicted to enable 3'-5'-exoribonuclease activity involved in mature miRNA 3'-end processing. Involved in olfactory learning and regulatory ncRNA-mediated post-transcriptional gene silencing. Located in cytosol; mutator focus; and nucleus. Expressed in AWCL; AWCR; and somatic cell. Is an ortholog of human EXD3 (exonuclease 3'-5' domain containing 3). | Paper_evidence | WBPaper00065943 | ||||||
Curator_confirmed | WBPerson324 | ||||||||
WBPerson37462 | |||||||||
Inferred_automatically | This description was generated automatically by a script based on data from the WS292 version of WormBase | ||||||||
Date_last_updated | 24 Apr 2024 00:00:00 | ||||||||
Molecular_info | Corresponding_CDS | ZK1098.8 | |||||||
Corresponding_transcript | ZK1098.8.1 | ||||||||
Other_sequence | CR03715 | ||||||||
CBC14770_1 | |||||||||
CRC08288_1 | |||||||||
Associated_feature | WBsf667292 | ||||||||
WBsf667293 | |||||||||
WBsf227313 | |||||||||
Experimental_info | RNAi_result (12) | ||||||||
Expr_pattern (11) | |||||||||
Drives_construct | WBCnstr00003803 | ||||||||
WBCnstr00014695 | |||||||||
WBCnstr00014696 | |||||||||
WBCnstr00018512 | |||||||||
WBCnstr00036084 | |||||||||
Construct_product | WBCnstr00014695 | ||||||||
WBCnstr00014696 | |||||||||
WBCnstr00018512 | |||||||||
WBCnstr00036084 | |||||||||
Antibody | WBAntibody00000828 | ||||||||
Microarray_results (20) | |||||||||
Expression_cluster (133) | |||||||||
Interaction (31) | |||||||||
WBProcess | WBbiopr:00000057 | ||||||||
Map_info (4) | |||||||||
Reference (129) | |||||||||
Remark | Sequence connection from [Ketting RF] | ||||||||
Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | ||||||||
Method | Gene |