WormBase Tree Display for Gene: WBGene00003011
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WBGene00003011 | SMap | S_parent | Sequence | CHROMOSOME_V | |||||
---|---|---|---|---|---|---|---|---|---|
Identity | Version | 2 | |||||||
Name | CGC_name | lin-25 | Person_evidence | WBPerson261 | |||||
Sequence_name | F56H9.5 | ||||||||
Molecular_name | F56H9.5 | ||||||||
F56H9.5.1 | |||||||||
CE05975 | |||||||||
Other_name | mdt-24 | Person_evidence | WBPerson3947 | ||||||
CELE_F56H9.5 | Accession_evidence | NDB | BX284605 | ||||||
Public_name | lin-25 | ||||||||
DB_info | Database | AceView | gene | 5N137 | |||||
WormQTL | gene | WBGene00003011 | |||||||
SignaLink | protein | WBGene00003011 | |||||||
WormFlux | gene | WBGene00003011 | |||||||
NDB | locus_tag | CELE_F56H9.5 | |||||||
NCBI | gene | 179732 | |||||||
RefSeq | protein | NM_073761.8 | |||||||
SwissProt | UniProtAcc | Q10573 | |||||||
TREEFAM | TREEFAM_ID | TF316646 | |||||||
UniProt_GCRP | UniProtAcc | Q10573 | |||||||
Species | Caenorhabditis elegans | ||||||||
History | Version_change | 1 | 07 Apr 2004 11:29:30 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
2 | 12 Nov 2014 12:54:52 | WBPerson2970 | Name_change | Other_name | mdt-24 | ||||
Status | Live | ||||||||
Gene_info | Biotype | SO:0001217 | |||||||
Gene_class | lin | ||||||||
Reference_allele | WBVar00144008 | ||||||||
Allele (91) | |||||||||
Legacy_information | e1446 : adult hermaphrodite vulvaless 11% sterile. ES2. HME1. Males morphologically wildtype ME0. NA2 (n545ts (at 25x resembles e1446 at 15x 8% Vul)). | ||||||||
[Tuck SP] lin for lineage abnormal. Hermaphrodites are Egl | |||||||||
See also e1446, n545, n1062, n1063 | |||||||||
[C.elegansII] e1446 : adult hermaphrodite vulvaless,11% sterile. VPC all 3ary except P6.p. Suppresses lin-1, let-60(gf), not lin-12(gf).ES2. HME1. Males morphologically wildtype ME0. OA9: n545ts (at 25C resembles e1446, at 15C 8% Vul), n1063, ku78, ar90 (probable null, resembles e1446), etc. Cloned: encodes predicted 1139 aa novel protein. [Tuck and Greenwald 1995; GS] | |||||||||
Strain | WBStrain00026528 | ||||||||
WBStrain00026804 | |||||||||
WBStrain00026902 | |||||||||
WBStrain00027100 | |||||||||
WBStrain00005521 | |||||||||
WBStrain00008013 | |||||||||
WBStrain00008017 | |||||||||
RNASeq_FPKM (74) | |||||||||
GO_annotation (15) | |||||||||
Ortholog (27) | |||||||||
Structured_description | Concise_description | lin-25 encodes a divergent homolog of the TRAP100/Med24 subunit of the Mediator complex; during development, lin-25 functions downstream of let-60 ras to regulate fate specification and differentiation of a number of cell types such as the vulval precursor cells; targets of LIN-25 activity include the lin-39 Hox gene, whose transcriptional upregulation during vulval cell fate specification is dependent upon lin-25; LIN-25 is expressed in vulval precursor cells, hypodermal seam cells, and cells in the somatic gonad; LIN-25 is detected in nuclei, but also seen in the cytoplasm. | Paper_evidence | WBPaper00003330 | |||||
WBPaper00004407 | |||||||||
WBPaper00027035 | |||||||||
WBPaper00035311 | |||||||||
Curator_confirmed | WBPerson1843 | ||||||||
Date_last_updated | 03 May 2007 00:00:00 | ||||||||
Automated_description | Involved in defense response to Gram-positive bacterium and vulval development. Acts upstream of or within with a positive effect on cell fate specification. Located in cytoplasm and nucleus. Expressed in several structures, including P3.p hermaphrodite; P4.p hermaphrodite; P8.p hermaphrodite; hermaphrodite distal tip cell; and vulval cell. | Paper_evidence | WBPaper00065943 | ||||||
Curator_confirmed | WBPerson324 | ||||||||
WBPerson37462 | |||||||||
Inferred_automatically | This description was generated automatically by a script based on data from the WS292 version of WormBase | ||||||||
Date_last_updated | 24 Apr 2024 00:00:00 | ||||||||
Molecular_info | Corresponding_CDS | F56H9.5 | |||||||
Corresponding_transcript | F56H9.5.1 | ||||||||
Other_sequence | CJC16777 | ||||||||
Associated_feature | WBsf647392 | ||||||||
WBsf661921 | |||||||||
WBsf1001624 | |||||||||
WBsf1020604 | |||||||||
WBsf232679 | |||||||||
WBsf232680 | |||||||||
WBsf232681 | |||||||||
Experimental_info | RNAi_result | WBRNAi00067753 | Inferred_automatically | RNAi_primary | |||||
WBRNAi00095285 | Inferred_automatically | RNAi_primary | |||||||
WBRNAi00048794 | Inferred_automatically | RNAi_primary | |||||||
WBRNAi00067528 | Inferred_automatically | RNAi_primary | |||||||
WBRNAi00015856 | Inferred_automatically | RNAi_primary | |||||||
Expr_pattern | Expr1293 | ||||||||
Expr1023216 | |||||||||
Expr1031405 | |||||||||
Expr1152543 | |||||||||
Expr2013169 | |||||||||
Expr2031401 | |||||||||
Drives_construct | WBCnstr00004617 | ||||||||
WBCnstr00004618 | |||||||||
WBCnstr00036286 | |||||||||
Construct_product | WBCnstr00004617 | ||||||||
WBCnstr00004618 | |||||||||
WBCnstr00036286 | |||||||||
Antibody | WBAntibody00000201 | ||||||||
Microarray_results (20) | |||||||||
Expression_cluster (113) | |||||||||
Interaction (66) | |||||||||
Map_info | Map | V | Position | 4.60018 | Error | 0.006913 | |||
Well_ordered | |||||||||
Positive | Positive_clone | F56H9 | Inferred_automatically | From sequence, transcript, pseudogene data | |||||
YSL59 | |||||||||
Negative | Negative_clone | W05B10 | |||||||
Mapping_data | 2_point | 6095 | |||||||
6096 | |||||||||
6097 | |||||||||
6098 | |||||||||
Multi_point (25) | |||||||||
Pos_neg_data (3) | |||||||||
Reference (69) | |||||||||
Method | Gene |