WormBase Tree Display for Gene: WBGene00002019
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| WBGene00002019 | SMap | S_parent | Sequence | T27E4 | |||||
|---|---|---|---|---|---|---|---|---|---|
| Identity | Version | 1 | |||||||
| Name | CGC_name | hsp-16.48 | Person_evidence | WBPerson36 | |||||
| Sequence_name | T27E4.3 | ||||||||
| Molecular_name | T27E4.3 | ||||||||
| T27E4.3.1 | |||||||||
| CE14251 | |||||||||
| Other_name | hsp-16 | ||||||||
| CELE_T27E4.3 | Accession_evidence | NDB | BX284605 | ||||||
| Public_name | hsp-16.48 | ||||||||
| DB_info | Database | AceView | gene | 5J569 | |||||
| WormQTL | gene | WBGene00002019 | |||||||
| WormFlux | gene | WBGene00002019 | |||||||
| NDB | locus_tag | CELE_T27E4.3 | |||||||
| Panther | gene | CAEEL|WormBase=WBGene00002019|UniProtKB=P02513 | |||||||
| family | PTHR45640 | ||||||||
| NCBI | gene | 179287 | |||||||
| RefSeq | protein | NM_072954.5 | |||||||
| SwissProt | UniProtAcc | P02513 | |||||||
| UniProt_GCRP | UniProtAcc | P02513 | |||||||
| OMIM | gene | 123580 | |||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 07 Apr 2004 11:29:26 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | hsp | ||||||||
| Allele | WBVar00091863 | Inferred_automatically | From strain object: RB791 | ||||||
| WBVar01499903 | |||||||||
| WBVar01500129 | |||||||||
| WBVar01499419 | |||||||||
| WBVar01499420 | |||||||||
| WBVar01499056 | |||||||||
| WBVar01499249 | |||||||||
| WBVar01499316 | |||||||||
| Strain | WBStrain00030548 | ||||||||
| WBStrain00030720 | |||||||||
| WBStrain00030838 | |||||||||
| WBStrain00031504 | |||||||||
| WBStrain00034987 | |||||||||
| In_cluster | HSP16A | ||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation (14) | |||||||||
| Ortholog (91) | |||||||||
| Paralog (17) | |||||||||
| Structured_description | Concise_description | hsp-16.48 encodes a 16-kD heat shock protein (HSP) that is a member of the hsp16/hsp20/alphaB-crystallin (HSP16) family of heat shock proteins; an hsp-16.48 reporter fusion, expressed broadly but most strongly in body muscle and hypodermis, is induced solely in response to heat shock or other environmental stresses; expression is detectable in somatic tissues in post-gastrulation embryos, all larval stages, and in adults; HSP-16.48 is likely to function as a passive ligand temporarily preventing unfolded proteins from aggregating. | Paper_evidence | WBPaper00001187 | |||||
| WBPaper00001497 | |||||||||
| WBPaper00004424 | |||||||||
| WBPaper00013029 | |||||||||
| WBPaper00013239 | |||||||||
| WBPaper00013280 | |||||||||
| Curator_confirmed | WBPerson1843 | ||||||||
| Date_last_updated | 05 Nov 2004 00:00:00 | ||||||||
| Automated_description | Predicted to enable unfolded protein binding activity. Involved in determination of adult lifespan; endoplasmic reticulum unfolded protein response; and response to heat. Predicted to be located in cytoplasm and nucleus. Expressed in several structures, including coelomocyte; enteric muscle; intestine; nervous system; and pharynx. Human ortholog(s) of this gene implicated in cataract 9 multiple types. Is an ortholog of human CRYAA (crystallin alpha A). | Paper_evidence | WBPaper00065943 | ||||||
| WBPaper00067038 | |||||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS296 version of WormBase | ||||||||
| Date_last_updated | 20 Mar 2025 00:00:00 | ||||||||
| Disease_info | Potential_model | DOID:0110266 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:2388) | ||||
| Molecular_info | Corresponding_CDS | T27E4.3 | |||||||
| Corresponding_transcript | T27E4.3.1 | ||||||||
| Other_sequence (31) | |||||||||
| Associated_feature | WBsf977960 | ||||||||
| WBsf977961 | |||||||||
| WBsf977963 | |||||||||
| WBsf232205 | |||||||||
| Experimental_info | RNAi_result | WBRNAi00093732 | Inferred_automatically | RNAi_primary | |||||
| WBRNAi00063167 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00106385 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00106384 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00027602 | Inferred_automatically | RNAi_primary | |||||||
| Expr_pattern | Expr1381 | ||||||||
| Expr15006 | |||||||||
| Expr15519 | |||||||||
| Expr1028019 | |||||||||
| Expr1157857 | |||||||||
| Expr1200271 | |||||||||
| Expr2012620 | |||||||||
| Expr2030856 | |||||||||
| Drives_construct (24) | |||||||||
| Construct_product | WBCnstr00010254 | ||||||||
| WBCnstr00016623 | |||||||||
| WBCnstr00016624 | |||||||||
| WBCnstr00019264 | |||||||||
| WBCnstr00036517 | |||||||||
| WBCnstr00042210 | |||||||||
| Antibody | WBAntibody00001859 | ||||||||
| Microarray_results (21) | |||||||||
| Expression_cluster (267) | |||||||||
| Interaction (40) | |||||||||
| Map_info | Map | V | Position | 1.92471 | Error | 0.000457 | |||
| Positive | Positive_clone | T27E4 | Inferred_automatically | From sequence, transcript, pseudogene data | |||||
| Mapping_data | Multi_point | 4419 | |||||||
| Pseudo_map_position | |||||||||
| Reference (73) | |||||||||
| Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||||
| Method | Gene |
