WormBase Tree Display for Gene: WBGene00001978
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WBGene00001978 | SMap | S_parent | Sequence | R13H4 | |||||
---|---|---|---|---|---|---|---|---|---|
Identity | Version | 1 | |||||||
Name | CGC_name | hmp-1 | Person_evidence | WBPerson498 | |||||
Sequence_name | R13H4.4 | ||||||||
Molecular_name (19) | |||||||||
Other_name | CELE_R13H4.4 | Accession_evidence | NDB | BX284605 | |||||
Public_name | hmp-1 | ||||||||
DB_info | Database (11) | ||||||||
Species | Caenorhabditis elegans | ||||||||
History | Version_change | 1 | 07 Apr 2004 11:29:26 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
Status | Live | ||||||||
Gene_info | Biotype | SO:0001217 | |||||||
Gene_class | hmp | ||||||||
Allele (102) | |||||||||
Legacy_information | [C.elegansII] Mutations zygotic lethal, arrest at 1.25-1.5 fold stage with lumps in dorsal hypoderm. Cloned: encodes probable alpha-catenin homolog. [JJ] | ||||||||
Strain | WBStrain00001826 | ||||||||
WBStrain00022476 | |||||||||
WBStrain00024213 | |||||||||
WBStrain00030631 | |||||||||
RNASeq_FPKM (74) | |||||||||
GO_annotation (27) | |||||||||
Ortholog (46) | |||||||||
Paralog | WBGene00000832 | Caenorhabditis elegans | From_analysis | TreeFam | |||||
WormBase-Compara | |||||||||
WBGene00000942 | Caenorhabditis elegans | From_analysis | TreeFam | ||||||
WormBase-Compara | |||||||||
Structured_description | Concise_description | hmp-1 encodes an alpha-catenin; during development, hmp-1 activity is required for proper enclosure and elongation of the embryo; HMP-1 localizes to hypodermal adherens junctions. | Paper_evidence | WBPaper00003046 | |||||
Curator_confirmed | WBPerson1843 | ||||||||
Date_last_updated | 11 Jun 2008 00:00:00 | ||||||||
Automated_description | Enables actin filament binding activity and beta-catenin binding activity. Involved in several processes, including cortical actin cytoskeleton organization; embryonic morphogenesis; and regulation of actin cytoskeleton organization. Located in adherens junction and apical junction complex. Part of catenin complex. Expressed in several structures, including distal tip cell; germ cell; intestinal cell; neuroblasts; and pharyngeal cell. Human ortholog(s) of this gene implicated in several diseases, including arrhythmogenic right ventricular dysplasia 13; cervix uteri carcinoma in situ; and urinary system cancer (multiple). Is an ortholog of human CTNNA2 (catenin alpha 2). | Paper_evidence | WBPaper00065943 | ||||||
Curator_confirmed | WBPerson324 | ||||||||
WBPerson37462 | |||||||||
Inferred_automatically | This description was generated automatically by a script based on data from the WS292 version of WormBase | ||||||||
Date_last_updated | 24 Apr 2024 00:00:00 | ||||||||
Disease_info | Potential_model | DOID:8991 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:2509) | ||||
DOID:11054 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:2509) | ||||||
DOID:0090131 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:2510) | ||||||
DOID:2671 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:2509) | ||||||
DOID:0060864 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:2509) | ||||||
DOID:0110084 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:2511) | ||||||
DOID:4450 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:2509) | ||||||
DOID:10283 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:2509) | ||||||
DOID:3457 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:2509) | ||||||
Molecular_info | Corresponding_CDS | R13H4.4a | |||||||
R13H4.4b | |||||||||
R13H4.4c | |||||||||
R13H4.4d | |||||||||
R13H4.4e | |||||||||
R13H4.4f | |||||||||
Corresponding_transcript (7) | |||||||||
Other_sequence (49) | |||||||||
Associated_feature (11) | |||||||||
Experimental_info | RNAi_result (18) | ||||||||
Expr_pattern | Chronogram912 | ||||||||
Expr6534 | |||||||||
Expr9341 | |||||||||
Expr13047 | |||||||||
Expr14677 | |||||||||
Expr1011130 | |||||||||
Expr1031148 | |||||||||
Expr1155584 | |||||||||
Expr2012529 | |||||||||
Expr2030768 | |||||||||
Drives_construct | WBCnstr00002622 | ||||||||
WBCnstr00004619 | |||||||||
WBCnstr00006235 | |||||||||
WBCnstr00007873 | |||||||||
WBCnstr00008029 | |||||||||
WBCnstr00009117 | |||||||||
WBCnstr00020495 | |||||||||
WBCnstr00036545 | |||||||||
Construct_product | WBCnstr00020495 | ||||||||
WBCnstr00036545 | |||||||||
Antibody | WBAntibody00000167 | ||||||||
WBAntibody00001450 | |||||||||
WBAntibody00002691 | |||||||||
Microarray_results (30) | |||||||||
Expression_cluster (137) | |||||||||
Interaction (117) | |||||||||
WBProcess | WBbiopr:00000017 | ||||||||
Map_info | Map | V | Position | 3.46447 | Error | 0.012439 | |||
Positive | Positive_clone | R13H4 | Inferred_automatically | From sequence, transcript, pseudogene data | |||||
Mapping_data | Multi_point | 4408 | |||||||
5036 | |||||||||
Pseudo_map_position | |||||||||
Reference (108) | |||||||||
Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||||
Method | Gene |