WormBase Tree Display for Gene: WBGene00001974
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WBGene00001974 | Evidence | CGC_data_submission | |||||||
---|---|---|---|---|---|---|---|---|---|
SMap | S_parent | Sequence | T20B12 | ||||||
Identity | Version | 1 | |||||||
Name | CGC_name | hmg-4 | |||||||
Sequence_name | T20B12.8 | ||||||||
Molecular_name | T20B12.8 | ||||||||
T20B12.8.1 | |||||||||
CE01414 | |||||||||
Other_name | CELE_T20B12.8 | Accession_evidence | NDB | BX284603 | |||||
Public_name | hmg-4 | ||||||||
DB_info | Database | AceView | gene | 3I470 | |||||
WormQTL | gene | WBGene00001974 | |||||||
WormFlux | gene | WBGene00001974 | |||||||
NDB | locus_tag | CELE_T20B12.8 | |||||||
Panther | gene | CAEEL|WormBase=WBGene00001974|UniProtKB=P41848 | |||||||
family | PTHR45849 | ||||||||
NCBI | gene | 176052 | |||||||
RefSeq | protein | NM_066232.7 | |||||||
SwissProt | UniProtAcc | P41848 | |||||||
TREEFAM | TREEFAM_ID | TF315228 | |||||||
UniProt_GCRP | UniProtAcc | P41848 | |||||||
Species | Caenorhabditis elegans | ||||||||
History | Version_change | 1 | 07 Apr 2004 11:29:26 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
Status | Live | ||||||||
Gene_info | Biotype | SO:0001217 | |||||||
Gene_class | hmg | ||||||||
Allele (28) | |||||||||
RNASeq_FPKM (74) | |||||||||
GO_annotation (16) | |||||||||
Contained_in_operon | CEOP3432 | ||||||||
Ortholog (40) | |||||||||
Paralog | WBGene00001973 | Caenorhabditis elegans | From_analysis | TreeFam | |||||
Inparanoid_8 | |||||||||
Panther | |||||||||
WormBase-Compara | |||||||||
WBGene00001972 | Caenorhabditis elegans | From_analysis | WormBase-Compara | ||||||
WBGene00008081 | Caenorhabditis elegans | From_analysis | WormBase-Compara | ||||||
WBGene00012209 | Caenorhabditis elegans | From_analysis | WormBase-Compara | ||||||
WBGene00022182 | Caenorhabditis elegans | From_analysis | WormBase-Compara | ||||||
Structured_description | Concise_description | hmg-4 encodes a protein with strong similarity to the highly conserved high mobility group protein SSRP1 (structure-specific DNA recognition protein); by homology, HMG-4 is predicted to be a member of the FACT (facilitates chromatin transcription) complex that functions as a transcription elongation factor; RNAi experiments indicate that hmg-4 is required for locomotion and larval development, and required redundantly with hmg-3, its paralog, for embryonic development. | Paper_evidence | WBPaper00018389 | |||||
WBPaper00018725 | |||||||||
Curator_confirmed | WBPerson1843 | ||||||||
Date_last_updated | 17 Jun 2004 00:00:00 | ||||||||
Automated_description | Predicted to enable histone binding activity and nucleosome binding activity. Involved in nematode pharynx development and regulation of embryonic development. Located in nucleus. Expressed in several structures, including coelomocyte; head muscle; neurons; somatic cell; and somatic nervous system. Is an ortholog of human SSRP1 (structure specific recognition protein 1). | Paper_evidence | WBPaper00065943 | ||||||
Curator_confirmed | WBPerson324 | ||||||||
WBPerson37462 | |||||||||
Inferred_automatically | This description was generated automatically by a script based on data from the WS292 version of WormBase | ||||||||
Date_last_updated | 24 Apr 2024 00:00:00 | ||||||||
Molecular_info | Corresponding_CDS | T20B12.8 | |||||||
Corresponding_transcript | T20B12.8.1 | ||||||||
Other_sequence (65) | |||||||||
Associated_feature | WBsf651203 | ||||||||
WBsf655453 | |||||||||
WBsf667074 | |||||||||
WBsf667075 | |||||||||
WBsf667076 | |||||||||
WBsf978766 | |||||||||
WBsf226976 | |||||||||
WBsf226977 | |||||||||
Transcription_factor | WBTranscriptionFactor000348 | ||||||||
Experimental_info | RNAi_result (41) | ||||||||
Expr_pattern | Expr7669 | ||||||||
Expr13852 | |||||||||
Expr1016203 | |||||||||
Expr1031144 | |||||||||
Expr1157147 | |||||||||
Expr2012521 | |||||||||
Expr2030760 | |||||||||
Drives_construct | WBCnstr00012814 | ||||||||
WBCnstr00036549 | |||||||||
Construct_product | WBCnstr00016596 | ||||||||
WBCnstr00036549 | |||||||||
WBCnstr00038803 | |||||||||
Regulate_expr_cluster | WBPaper00055013:hmg-4(RNAi)_downregulated | ||||||||
WBPaper00055013:hmg-4(RNAi)_upregulated | |||||||||
WBPaper00055013:HMG-4_interacting_protein | |||||||||
Microarray_results (25) | |||||||||
Expression_cluster (140) | |||||||||
Interaction (330) | |||||||||
Map_info | Map | III | Position | -0.742919 | Error | 0.002225 | |||
Positive | Positive_clone | T20B12 | Inferred_automatically | From sequence, transcript, pseudogene data | |||||
Mapping_data | Multi_point | 5263 | |||||||
4724 | |||||||||
Pseudo_map_position | |||||||||
Reference (13) | |||||||||
Remark | Sequence connection from [Sugimoto A] | ||||||||
Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | ||||||||
Method | Gene |