WormBase Tree Display for Gene: WBGene00001207
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| WBGene00001207 | SMap | S_parent | Sequence | R53 | |||||
|---|---|---|---|---|---|---|---|---|---|
| Identity | Version | 1 | |||||||
| Name | CGC_name | egl-43 | Person_evidence | WBPerson268 | |||||
| Sequence_name | R53.3 | ||||||||
| Molecular_name | R53.3a | ||||||||
| R53.3a.1 | |||||||||
| CE03572 | |||||||||
| R53.3b | |||||||||
| CE03573 | |||||||||
| R53.3b.1 | |||||||||
| R53.3b.2 | |||||||||
| R53.3c | |||||||||
| Other_name | CELE_R53.3 | Accession_evidence | NDB | BX284602 | |||||
| Public_name | egl-43 | ||||||||
| DB_info | Database (13) | ||||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 07 Apr 2004 11:29:23 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | egl | ||||||||
| Allele (146) | |||||||||
| Legacy_information | n997 : moderate bloating Type B. HSN cell bodies serotonin- positive but misplaced posteriorly along path of HSN migration; aberrant variable HSN processes. ES2 (adult) ES1 (other stages). NA2 (n1079). | ||||||||
| See also n997, n1079 | |||||||||
| [C.elegansII] n997 : moderate bloating; stimulated by serotonin, not imipramine. HSN cell bodies serotonin-positive but misplaced posteriorly along path of HSN migration; aberrant variable HSN processes; abnormal IL2 wiring. ES2 (adult) ES1 (other stages). ME2. OA1: n1079. Cloned: 2.5 and 1.8 kb transcripts, encode 517 aa or360 aa zinc finger proteins, related to mouse Evi-1. [Desai and Horvitz 1989; Garriga and Stern 1994; KP; MT; NG] | |||||||||
| Strain | WBStrain00026951 | ||||||||
| WBStrain00027008 | |||||||||
| WBStrain00027009 | |||||||||
| WBStrain00027071 | |||||||||
| WBStrain00030688 | |||||||||
| WBStrain00033860 | |||||||||
| WBStrain00047248 | |||||||||
| WBStrain00047250 | |||||||||
| WBStrain00054724 | |||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation (23) | |||||||||
| Ortholog (41) | |||||||||
| Paralog | WBGene00000483 | Caenorhabditis elegans | From_analysis | Panther | |||||
| WBGene00003015 | Caenorhabditis elegans | From_analysis | Panther | ||||||
| WBGene00013240 | Caenorhabditis elegans | From_analysis | Panther | ||||||
| WBGene00016905 | Caenorhabditis elegans | From_analysis | Panther | ||||||
| WBGene00009448 | Caenorhabditis elegans | From_analysis | Panther | ||||||
| Structured_description | Concise_description | egl-43 encodes a zinc finger protein that affects HSN cell migration and development of the phasmid neurons; expressed in the HSN and phasmid neurons. | Paper_evidence | WBPaper00001105 | |||||
| WBPaper00001836 | |||||||||
| WBPaper00003422 | |||||||||
| Curator_confirmed | WBPerson48 | ||||||||
| Date_last_updated | 17 Jun 2004 00:00:00 | ||||||||
| Automated_description | Enables DNA-binding transcription factor activity. Involved in several processes, including regulation of developmental process; regulation of mitotic cell cycle; and regulation of transcription by RNA polymerase II. Located in nucleus. Expressed in several structures, including MSaaap; MSpaap; gonad; neurons; and somatic gonad precursor. Human ortholog(s) of this gene implicated in dilated cardiomyopathy 1LL and myeloid neoplasm. Is an ortholog of human MECOM (MDS1 and EVI1 complex locus) and PRDM16 (PR/SET domain 16). | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS292 version of WormBase | ||||||||
| Date_last_updated | 24 Apr 2024 00:00:00 | ||||||||
| Disease_info | Potential_model | EFO:MONDO:0011555 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:3498) | ||||
| DOID:0081157 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:14000) | ||||||
| DOID:0070004 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:3498) | ||||||
| Molecular_info | Corresponding_CDS | R53.3a | |||||||
| R53.3b | |||||||||
| Corresponding_transcript (4) | |||||||||
| Corresponding_transcript_history | R53.3c:wp248 | ||||||||
| Other_sequence (16) | |||||||||
| Associated_feature (25) | |||||||||
| Gene_product_binds | WBsf038811 | ||||||||
| WBsf038815 | |||||||||
| WBsf038818 | |||||||||
| WBsf038819 | |||||||||
| WBsf919669 | |||||||||
| Transcription_factor | WBTranscriptionFactor000128 | ||||||||
| Experimental_info | RNAi_result (44) | ||||||||
| Expr_pattern | Expr669 | ||||||||
| Expr4501 | |||||||||
| Expr4761 | |||||||||
| Expr11260 | |||||||||
| Expr15011 | |||||||||
| Expr1016323 | |||||||||
| Expr1030766 | |||||||||
| Expr1155673 | |||||||||
| Expr2011222 | |||||||||
| Expr2029458 | |||||||||
| Drives_construct | WBCnstr00006142 | ||||||||
| WBCnstr00006143 | |||||||||
| WBCnstr00012064 | |||||||||
| WBCnstr00012225 | |||||||||
| WBCnstr00018524 | |||||||||
| WBCnstr00037034 | |||||||||
| Construct_product | WBCnstr00012064 | ||||||||
| WBCnstr00018524 | |||||||||
| WBCnstr00037034 | |||||||||
| Regulate_expr_cluster | WBPaper00059471:EGL-43_interacting | ||||||||
| Antibody | WBAntibody00000214 | ||||||||
| WBAntibody00000971 | |||||||||
| WBAntibody00001537 | |||||||||
| Microarray_results (31) | |||||||||
| Expression_cluster (146) | |||||||||
| Interaction (105) | |||||||||
| Map_info | Map | II | Position | 1.81525 | Error | 0.002697 | |||
| Well_ordered | |||||||||
| Positive | Positive_clone | R53 | Inferred_automatically | From sequence, transcript, pseudogene data | |||||
| W02B7 | Inferred_automatically | From sequence, transcript, pseudogene data | |||||||
| Mapping_data | Multi_point | 844 | |||||||
| 845 | |||||||||
| 1065 | |||||||||
| 1385 | |||||||||
| 5451 | |||||||||
| Pos_neg_data | 3190 | ||||||||
| 3227 | |||||||||
| 3228 | |||||||||
| 3229 | |||||||||
| 3230 | |||||||||
| 3231 | |||||||||
| 3234 | |||||||||
| Reference (46) | |||||||||
| Method | Gene |
