WormBase Tree Display for Gene: WBGene00000890
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| WBGene00000890 | SMap | S_parent | Sequence | CHROMOSOME_I | |||||
|---|---|---|---|---|---|---|---|---|---|
| Identity | Version | 3 | |||||||
| Name | CGC_name | sig-7 | Person_evidence | WBPerson510 | |||||
| WBPerson313 | |||||||||
| WBPerson466 | |||||||||
| Sequence_name | F39H2.2 | ||||||||
| Molecular_name | F39H2.2a | ||||||||
| F39H2.2a.1 | |||||||||
| CE32410 | |||||||||
| F39H2.2b | |||||||||
| CE32411 | |||||||||
| F39H2.2b.1 | |||||||||
| Other_name | cyp-14 | Person_evidence | WBPerson466 | ||||||
| cyn-14 | Person_evidence | WBPerson466 | |||||||
| CELE_F39H2.2 | Accession_evidence | NDB | BX284601 | ||||||
| Public_name | sig-7 | ||||||||
| DB_info | Database (12) | ||||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 07 Apr 2004 11:29:21 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
| 2 | 20 Sep 2004 16:20:03 | WBPerson1971 | Name_change | CGC_name | cyp-14 -> cyn-14 | ||||
| 3 | 05 Jan 2006 11:22:21 | WBPerson2970 | Name_change | CGC_name | sig-7 | ||||
| Other_name | cyn-14 | ||||||||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | sig | ||||||||
| Allele (50) | |||||||||
| Legacy_information | [Page AP] F39H2.2 No mutants known. | ||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation (24) | |||||||||
| Contained_in_operon | CEOP1492 | ||||||||
| Ortholog (35) | |||||||||
| Paralog (18) | |||||||||
| Structured_description | Concise_description | sig-7 encodes a predicted cyclophilin; loss of sig-7 activity via large-scale RNAi screens results in embryonic and larval lethality as well as reduced brood sizes, suggesting that SIG-7 plays an essential role during C. elegans development. | Paper_evidence | WBPaper00024497 | |||||
| WBPaper00024925 | |||||||||
| WBPaper00025054 | |||||||||
| WBPaper00026884 | |||||||||
| Curator_confirmed | WBPerson48 | ||||||||
| WBPerson1843 | |||||||||
| Date_last_updated | 20 Mar 2007 00:00:00 | ||||||||
| Automated_description | Enables RNA polymerase II complex binding activity. Involved in nematode larval development; positive regulation of developmental process; and transcription elongation-coupled chromatin remodeling. Located in euchromatin and nucleoplasm. Expressed in several structures, including intestine. Is an ortholog of human PPIL4 (peptidylprolyl isomerase like 4). | Paper_evidence | WBPaper00065943 | ||||||
| WBPaper00067038 | |||||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS296 version of WormBase | ||||||||
| Date_last_updated | 20 Mar 2025 00:00:00 | ||||||||
| Molecular_info | Corresponding_CDS | F39H2.2a | |||||||
| F39H2.2b | |||||||||
| Corresponding_CDS_history | F39H2.2:wp90 | ||||||||
| Corresponding_transcript | F39H2.2a.1 | ||||||||
| F39H2.2b.1 | |||||||||
| Other_sequence (36) | |||||||||
| Associated_feature | WBsf984474 | ||||||||
| WBsf218188 | |||||||||
| WBsf218189 | |||||||||
| Experimental_info | RNAi_result (14) | ||||||||
| Expr_pattern | Expr4666 | ||||||||
| Expr13018 | |||||||||
| Expr1022644 | |||||||||
| Expr1030555 | |||||||||
| Expr1150678 | |||||||||
| Expr2015818 | |||||||||
| Expr2034051 | |||||||||
| Drives_construct | WBCnstr00037217 | ||||||||
| Construct_product | WBCnstr00037217 | ||||||||
| Microarray_results (25) | |||||||||
| Expression_cluster (107) | |||||||||
| SAGE_tag | SAGE:tacggagaacaaggacg | Strand | Sense | ||||||
| Unambiguously_mapped | |||||||||
| SAGE:atagatctccggatcgg | Strand | Sense | |||||||
| Unambiguously_mapped | |||||||||
| SAGE:acgacgacgatcccgat | Strand | Antisense | |||||||
| SAGE:ttttactgttacagaat | Strand | Antisense | |||||||
| SAGE:ttttactgtt | Strand | Antisense | |||||||
| SAGE:acgacgacga | Strand | Antisense | |||||||
| SAGE:tacggagaac | Strand | Sense | |||||||
| Unambiguously_mapped | |||||||||
| SAGE:ttgatttctcacaatct | Strand | Sense | |||||||
| Unambiguously_mapped | |||||||||
| Interaction (47) | |||||||||
| Map_info | Map | I | Position | 3.01492 | Error | 0.000261 | |||
| Positive | Positive_clone | F39H2 | Inferred_automatically | From sequence, transcript, pseudogene data | |||||
| Pseudo_map_position | |||||||||
| Reference (11) | |||||||||
| Remark | This gene has been renamed with approval of the CGC (cyp-14->cyn-14) | Person_evidence | WBPerson466 | ||||||
| Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | ||||||||
| Method | Gene |
