WormBase Tree Display for Gene: WBGene00000866
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| WBGene00000866 | SMap | S_parent | Sequence | Y43E12A | |||||
|---|---|---|---|---|---|---|---|---|---|
| Identity | Version | 1 | |||||||
| Name | CGC_name | cyb-2.1 | |||||||
| Sequence_name | Y43E12A.1 | ||||||||
| Molecular_name | Y43E12A.1 | ||||||||
| Y43E12A.1.1 | |||||||||
| CE28122 | |||||||||
| Other_name | CELE_Y43E12A.1 | Accession_evidence | NDB | BX284604 | |||||
| Public_name | cyb-2.1 | ||||||||
| DB_info | Database | AceView | gene | 4L751 | |||||
| WormQTL | gene | WBGene00000866 | |||||||
| WormFlux | gene | WBGene00000866 | |||||||
| NDB | locus_tag | CELE_Y43E12A.1 | |||||||
| Panther | gene | CAEEL|WormBase=WBGene00000866|UniProtKB=O45926 | |||||||
| family | PTHR10177 | ||||||||
| NCBI | gene | 177994 | |||||||
| RefSeq | protein | NM_069646.8 | |||||||
| TREEFAM | TREEFAM_ID | TF101001 | |||||||
| TrEMBL | UniProtAcc | O45926 | |||||||
| UniProt_GCRP | UniProtAcc | O45926 | |||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 07 Apr 2004 11:29:21 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | cyb | ||||||||
| Allele (24) | |||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation (13) | |||||||||
| Contained_in_operon | CEOP4621 | ||||||||
| Ortholog (46) | |||||||||
| Paralog (13) | |||||||||
| Structured_description | Automated_description | Predicted to enable cyclin-dependent protein serine/threonine kinase regulator activity. Involved in anterior/posterior axis specification, embryo and oocyte maturation. Predicted to be located in cytoplasm; microtubule organizing center; and nucleus. Predicted to be part of cyclin-dependent protein kinase holoenzyme complex. Expressed in germ line. Used to study cardiovascular system disease. Human ortholog(s) of this gene implicated in several diseases, including in situ carcinoma; renal cell carcinoma; and reproductive organ cancer (multiple). Is an ortholog of human CCNB1 (cyclin B1). | Paper_evidence | WBPaper00065943 | |||||
| WBPaper00067038 | |||||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS296 version of WormBase | ||||||||
| Date_last_updated | 20 Mar 2025 00:00:00 | ||||||||
| Disease_info | Experimental_model | DOID:1287 | Homo sapiens | Paper_evidence | WBPaper00066660 | ||||
| Curator_confirmed | WBPerson324 | ||||||||
| Date_last_updated | 02 May 2024 00:00:00 | ||||||||
| Potential_model | DOID:2871 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:1579) | |||||
| DOID:4450 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:1579) | ||||||
| DOID:8719 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:1579) | ||||||
| DOID:2152 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:1579) | ||||||
| DOID:10283 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:1579) | ||||||
| DOID:2526 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:1579) | ||||||
| DOID:4362 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:1579) | ||||||
| DOID:1612 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:1579) | ||||||
| Models_disease_in_annotation | WBDOannot00001528 | ||||||||
| Molecular_info | Corresponding_CDS | Y43E12A.1 | |||||||
| Corresponding_CDS_history | Y43E12A.1:wp52 | ||||||||
| Corresponding_transcript | Y43E12A.1.1 | ||||||||
| Other_sequence | DN191008.1 | ||||||||
| EX006941.1 | |||||||||
| EX551057.1 | |||||||||
| AAC00308_1 | |||||||||
| CR08550 | |||||||||
| EX546722.1 | |||||||||
| HBC18463_1 | |||||||||
| Associated_feature | WBsf976961 | ||||||||
| WBsf997747 | |||||||||
| WBsf1018164 | |||||||||
| WBsf229075 | |||||||||
| Experimental_info | RNAi_result (18) | ||||||||
| Expr_pattern | Expr4132 | ||||||||
| Expr1030533 | |||||||||
| Expr1159948 | |||||||||
| Expr2010647 | |||||||||
| Expr2028887 | |||||||||
| Antibody | WBAntibody00003113 | ||||||||
| Microarray_results | SMD_Y43E12A.1 | ||||||||
| 172738_x_at | |||||||||
| A_12_P114640 | |||||||||
| A_12_P131770 | |||||||||
| Aff_Y43E12A.1 | |||||||||
| GPL3518_CE28122 | |||||||||
| GPL8304_CE_WBGene00000866_A | |||||||||
| GPL8304_CE_WBGene00000866_C | |||||||||
| GPL8673_Y43E12A_1P00048 | |||||||||
| GPL8673_Y43E12A_1P00161 | |||||||||
| Expression_cluster (200) | |||||||||
| Interaction (376) | |||||||||
| Map_info | Map | IV | Position | 4.77843 | Error | 0.003213 | |||
| Positive | Positive_clone | Y43E12A | Inferred_automatically | From CDS info | |||||
| From sequence, transcript, pseudogene data | |||||||||
| Mapping_data | Multi_point | 5507 | |||||||
| 5510 | |||||||||
| Pseudo_map_position | |||||||||
| Reference (20) | |||||||||
| Remark | Sequence connection from [van den Heuvel SJL], [020808 krb] | ||||||||
| Noe, this gene is not the same as cyb-2 which is now a secondary name for cyb-3 [020808 krb] | |||||||||
| Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | ||||||||
| Method | Gene |
