WormBase Tree Display for Gene: WBGene00000821
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WBGene00000821 | SMap | S_parent | Sequence | Y47H9C | |||||
---|---|---|---|---|---|---|---|---|---|
Identity | Version | 2 | |||||||
Name | CGC_name | csp-3 | Person_evidence | WBPerson576 | |||||
Sequence_name | Y47H9C.6 | ||||||||
Molecular_name | Y47H9C.6a | ||||||||
Y47H9C.6a.1 | |||||||||
CE27635 | |||||||||
Y47H9C.6b | |||||||||
Other_name | CELE_Y47H9C.6 | Accession_evidence | NDB | BX284601 | |||||
Public_name | csp-3 | ||||||||
DB_info | Database | AceView | gene | 1M480 | |||||
WormQTL | gene | WBGene00000821 | |||||||
WormFlux | gene | WBGene00000821 | |||||||
NDB | locus_tag | CELE_Y47H9C.6 | |||||||
Panther | gene | CAEEL|WormBase=WBGene00000821|UniProtKB=G5ECW5 | |||||||
family | PTHR10454 | ||||||||
NCBI | gene | 190006 | |||||||
RefSeq | protein | NM_060610.4 | |||||||
NR_138525.1 | |||||||||
SwissProt | UniProtAcc | G5ECW5 | |||||||
UniProt_GCRP | UniProtAcc | G5ECW5 | |||||||
RNAcentral | URSid | URS0000A040E4 | |||||||
Species | Caenorhabditis elegans | ||||||||
History | Version_change | 1 | 07 Apr 2004 11:29:21 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
2 | 19 Apr 2016 17:09:35 | WBPerson1983 | Event | Acquires_merge | WBGene00012957 | ||||
Acquires_merge | WBGene00012957 | ||||||||
Status | Live | ||||||||
Gene_info | Biotype | SO:0001217 | |||||||
Gene_class | csp | ||||||||
Allele (49) | |||||||||
Strain | WBStrain00032148 | ||||||||
WBStrain00027534 | |||||||||
RNASeq_FPKM (74) | |||||||||
GO_annotation (23) | |||||||||
Ortholog (16) | |||||||||
Paralog | WBGene00000417 | Caenorhabditis elegans | From_analysis | WormBase-Compara | |||||
WBGene00000819 | Caenorhabditis elegans | From_analysis | WormBase-Compara | ||||||
WBGene00000820 | Caenorhabditis elegans | From_analysis | WormBase-Compara | ||||||
Structured_description | Concise_description | csp-3 encodes a protein that is homologous to the C-terminal domain (small subunit) of caspase-like cysteine proteases, including CED-3; unlike other caspases, CSP-3 does not contain a middle or N-terminal domain; during development, csp-3 functions to negatively regulate programmed cell death; csp-3 activity is also required for embryonic development and coordinated locomotion; CSP-3 physically associates with CED-3 both in vitro and in vivo and can inhibit autoactivation of CED-3; a CSP-3::GFP reporter protein is expressed ubiquitously in embryos where it localizes to the cytoplasm. | Paper_evidence | WBPaper00003342 | |||||
WBPaper00004402 | |||||||||
WBPaper00032164 | |||||||||
Curator_confirmed | WBPerson1843 | ||||||||
Date_last_updated | 28 Jul 2009 00:00:00 | ||||||||
Automated_description | Enables caspase binding activity; cysteine-type endopeptidase inhibitor activity involved in apoptotic process; and zymogen binding activity. Involved in positive regulation of behavior; positive regulation of embryonic development; and regulation of apoptotic process. Located in cytoplasm. Expressed in several structures, including germ line. | Paper_evidence | WBPaper00065943 | ||||||
Curator_confirmed | WBPerson324 | ||||||||
WBPerson37462 | |||||||||
Inferred_automatically | This description was generated automatically by a script based on data from the WS292 version of WormBase | ||||||||
Date_last_updated | 24 Apr 2024 00:00:00 | ||||||||
Molecular_info | Corresponding_CDS | Y47H9C.6a | |||||||
Corresponding_CDS_history | Y47H9C.6:wp50 | ||||||||
Corresponding_transcript | Y47H9C.6b | ||||||||
Y47H9C.6a.1 | |||||||||
Other_sequence | AF088290 | ||||||||
Associated_feature | WBsf985407 | ||||||||
WBsf985408 | |||||||||
WBsf985409 | |||||||||
WBsf1010803 | |||||||||
Experimental_info | RNAi_result | WBRNAi00004667 | Inferred_automatically | RNAi_primary | |||||
WBRNAi00056851 | Inferred_automatically | RNAi_primary | |||||||
WBRNAi00058345 | Inferred_automatically | RNAi_primary | |||||||
WBRNAi00056846 | Inferred_automatically | RNAi_primary | |||||||
Expr_pattern | Expr8958 | ||||||||
Expr10792 | |||||||||
Expr1011429 | |||||||||
Expr1013265 | |||||||||
Expr1160298 | |||||||||
Expr1160302 | |||||||||
Expr2010559 | |||||||||
Expr2028799 | |||||||||
Drives_construct | WBCnstr00004605 | ||||||||
WBCnstr00013637 | |||||||||
Construct_product | WBCnstr00004605 | ||||||||
WBCnstr00013637 | |||||||||
Antibody | WBAntibody00001877 | ||||||||
Microarray_results (18) | |||||||||
Expression_cluster (82) | |||||||||
Interaction | WBInteraction000133984 | ||||||||
WBInteraction000133985 | |||||||||
WBInteraction000288549 | |||||||||
WBInteraction000303099 | |||||||||
WBInteraction000379964 | |||||||||
WBInteraction000420523 | |||||||||
WBInteraction000540820 | |||||||||
Map_info | Map | I | Position | 12.9054 | Error | 0.003378 | |||
Positive | Positive_clone | Y47H9C | Inferred_automatically | From CDS info | |||||
From sequence, transcript, pseudogene data | |||||||||
Mapping_data | Multi_point | 5594 | |||||||
Pseudo_map_position | |||||||||
Reference (21) | |||||||||
Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||||
Method | Gene |