WormBase Tree Display for Gene: WBGene00000821
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| WBGene00000821 | SMap | S_parent | Sequence | Y47H9C | |||||
|---|---|---|---|---|---|---|---|---|---|
| Identity | Version | 2 | |||||||
| Name | CGC_name | csp-3 | Person_evidence | WBPerson576 | |||||
| Sequence_name | Y47H9C.6 | ||||||||
| Molecular_name | Y47H9C.6a | ||||||||
| Y47H9C.6a.1 | |||||||||
| CE27635 | |||||||||
| Y47H9C.6b | |||||||||
| Other_name | CELE_Y47H9C.6 | Accession_evidence | NDB | BX284601 | |||||
| Public_name | csp-3 | ||||||||
| DB_info | Database (11) | ||||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 07 Apr 2004 11:29:21 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
| 2 | 19 Apr 2016 17:09:35 | WBPerson1983 | Event | Acquires_merge | WBGene00012957 | ||||
| Acquires_merge | WBGene00012957 | ||||||||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | csp | ||||||||
| Allele (49) | |||||||||
| Strain | WBStrain00032148 | ||||||||
| WBStrain00027534 | |||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation (15) | |||||||||
| Ortholog | CBOVI.g8214 | Caenorhabditis bovis | From_analysis | WormBase-Compara | |||||
| Cnig_chr_IV.g16094 | Caenorhabditis nigoni | From_analysis | WormBase-Compara | ||||||
| chrI_pilon.g2354 | Caenorhabditis elegans | From_analysis | WormBase-Compara | ||||||
| WBGene00286714 | Trichuris muris | From_analysis | WormBase-Compara | ||||||
| FB:FBgn0026404 | Drosophila melanogaster | From_analysis | EnsEMBL-Compara | ||||||
| PhylomeDB | |||||||||
| ZFIN:ZDB-GENE-070608-2 | Danio rerio | From_analysis | EnsEMBL-Compara | ||||||
| OrthoFinder | |||||||||
| PhylomeDB | |||||||||
| ZFIN:ZDB-GENE-060526-186 | Danio rerio | From_analysis | EnsEMBL-Compara | ||||||
| OrthoFinder | |||||||||
| PhylomeDB | |||||||||
| HGNC:1509 | Homo sapiens | From_analysis | EnsEMBL-Compara | ||||||
| OrthoFinder | |||||||||
| PhylomeDB | |||||||||
| RGD:620945 | Rattus norvegicus | From_analysis | EnsEMBL-Compara | ||||||
| OrthoFinder | |||||||||
| PhylomeDB | |||||||||
| Paralog | WBGene00000417 | Caenorhabditis elegans | From_analysis | WormBase-Compara | |||||
| WBGene00000819 | Caenorhabditis elegans | From_analysis | WormBase-Compara | ||||||
| WBGene00000820 | Caenorhabditis elegans | From_analysis | WormBase-Compara | ||||||
| Structured_description | Concise_description | csp-3 encodes a protein that is homologous to the C-terminal domain (small subunit) of caspase-like cysteine proteases, including CED-3; unlike other caspases, CSP-3 does not contain a middle or N-terminal domain; during development, csp-3 functions to negatively regulate programmed cell death; csp-3 activity is also required for embryonic development and coordinated locomotion; CSP-3 physically associates with CED-3 both in vitro and in vivo and can inhibit autoactivation of CED-3; a CSP-3::GFP reporter protein is expressed ubiquitously in embryos where it localizes to the cytoplasm. | Paper_evidence | WBPaper00003342 | |||||
| WBPaper00004402 | |||||||||
| WBPaper00032164 | |||||||||
| Curator_confirmed | WBPerson1843 | ||||||||
| Date_last_updated | 28 Jul 2009 00:00:00 | ||||||||
| Automated_description | Enables cysteine-type endopeptidase inhibitor activity and zymogen binding activity. Involved in negative regulation of apoptotic process involved in development and positive regulation of apoptotic process involved in development. Located in cytoplasm. Expressed in several structures, including germ line. | Paper_evidence | WBPaper00065943 | ||||||
| WBPaper00067038 | |||||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS296 version of WormBase | ||||||||
| Date_last_updated | 20 Mar 2025 00:00:00 | ||||||||
| Disease_info | Potential_model (11) | ||||||||
| Molecular_info | Corresponding_CDS | Y47H9C.6a | |||||||
| Corresponding_CDS_history | Y47H9C.6:wp50 | ||||||||
| Corresponding_transcript | Y47H9C.6b | ||||||||
| Y47H9C.6a.1 | |||||||||
| Other_sequence | AF088290 | ||||||||
| Associated_feature | WBsf985407 | ||||||||
| WBsf985408 | |||||||||
| WBsf985409 | |||||||||
| WBsf1010803 | |||||||||
| Experimental_info | RNAi_result | WBRNAi00004667 | Inferred_automatically | RNAi_primary | |||||
| WBRNAi00056851 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00058345 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00056846 | Inferred_automatically | RNAi_primary | |||||||
| Expr_pattern | Expr8958 | ||||||||
| Expr10792 | |||||||||
| Expr1011429 | |||||||||
| Expr1013265 | |||||||||
| Expr1160298 | |||||||||
| Expr1160302 | |||||||||
| Expr2010559 | |||||||||
| Expr2028799 | |||||||||
| Drives_construct | WBCnstr00004605 | ||||||||
| WBCnstr00013637 | |||||||||
| Construct_product | WBCnstr00004605 | ||||||||
| WBCnstr00013637 | |||||||||
| Antibody | WBAntibody00001877 | ||||||||
| Microarray_results (18) | |||||||||
| Expression_cluster (88) | |||||||||
| Interaction | WBInteraction000133984 | ||||||||
| WBInteraction000133985 | |||||||||
| WBInteraction000288549 | |||||||||
| WBInteraction000303099 | |||||||||
| WBInteraction000379964 | |||||||||
| WBInteraction000420523 | |||||||||
| WBInteraction000540820 | |||||||||
| Map_info | Map | I | Position | 12.9054 | Error | 0.003378 | |||
| Positive | Positive_clone | Y47H9C | Inferred_automatically | From CDS info | |||||
| From sequence, transcript, pseudogene data | |||||||||
| Mapping_data | Multi_point | 5594 | |||||||
| Pseudo_map_position | |||||||||
| Reference (21) | |||||||||
| Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||||
| Method | Gene |
