WormBase Tree Display for Gene: WBGene00000413
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| WBGene00000413 | SMap | S_parent | Sequence | Y54E10A | |||||
|---|---|---|---|---|---|---|---|---|---|
| Identity | Version | 1 | |||||||
| Name | CGC_name | cdt-1 | Person_evidence | WBPerson322 | |||||
| Sequence_name | Y54E10A.15 | ||||||||
| Molecular_name | Y54E10A.15 | ||||||||
| Y54E10A.15.1 | |||||||||
| CE22447 | |||||||||
| Other_name | CELE_Y54E10A.15 | Accession_evidence | NDB | BX284601 | |||||
| Public_name | cdt-1 | ||||||||
| DB_info | Database | WormQTL | gene | WBGene00000413 | |||||
| WormFlux | gene | WBGene00000413 | |||||||
| NDB | locus_tag | CELE_Y54E10A.15 | |||||||
| Panther | gene | CAEEL|WormBase=WBGene00000413|UniProtKB=Q86S68 | |||||||
| family | PTHR28637 | ||||||||
| NCBI | gene | 171896 | |||||||
| RefSeq | protein | NM_001047242.4 | |||||||
| TREEFAM | TREEFAM_ID | TF101159 | |||||||
| TrEMBL | UniProtAcc | Q86S68 | |||||||
| UniProt_GCRP | UniProtAcc | Q86S68 | |||||||
| OMIM | gene | 605525 | |||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 07 Apr 2004 11:29:20 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | cdt | ||||||||
| Allele (93) | |||||||||
| Strain | WBStrain00051136 | ||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation (18) | |||||||||
| Contained_in_operon | CEOP1944 | ||||||||
| Ortholog (29) | |||||||||
| Structured_description | Concise_description | cdt-1 encodes the C. elegans ortholog of the replication-licensing factor Cdt1; CDT-1 activity is essential for DNA replication; CDT-1 levels are negatively regulated by a CUL-4-containing ubiquitin ligase complex. | Paper_evidence | WBPaper00005912 | |||||
| WBPaper00028868 | |||||||||
| Curator_confirmed | WBPerson1843 | ||||||||
| Date_last_updated | 03 Dec 2007 00:00:00 | ||||||||
| Automated_description | Predicted to enable DNA binding activity and DNA polymerase binding activity. Involved in positive regulation of nematode male tail tip morphogenesis. Located in chromatin; cytoplasm; and nucleus. Expressed in anchor cell; germ line; uterine epithelial cell; and vulD. Human ortholog(s) of this gene implicated in Meier-Gorlin syndrome 4. Is an ortholog of human CDT1 (chromatin licensing and DNA replication factor 1). | Paper_evidence | WBPaper00065943 | ||||||
| WBPaper00067038 | |||||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS296 version of WormBase | ||||||||
| Date_last_updated | 20 Mar 2025 00:00:00 | ||||||||
| Disease_info | Potential_model | DOID:0080515 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:24576) | ||||
| Molecular_info | Corresponding_CDS | Y54E10A.15 | |||||||
| Corresponding_CDS_history | Y54E10A.15a:wp154 | ||||||||
| Y54E10A.15b:wp102 | |||||||||
| Y54E10A.15b:wp154 | |||||||||
| Corresponding_transcript | Y54E10A.15.1 | ||||||||
| Other_sequence | CJC07546_1 | ||||||||
| CR06574 | |||||||||
| CRC10573_1 | |||||||||
| CBC14493_1 | |||||||||
| CRC01944_1 | |||||||||
| CBC05093_1 | |||||||||
| JI468640.1 | |||||||||
| CR00767 | |||||||||
| CBC05545_1 | |||||||||
| Associated_feature | WBsf649013 | ||||||||
| WBsf976651 | |||||||||
| WBsf976652 | |||||||||
| WBsf983088 | |||||||||
| WBsf219111 | |||||||||
| Experimental_info | RNAi_result (26) | ||||||||
| Expr_pattern (12) | |||||||||
| Drives_construct | WBCnstr00000442 | ||||||||
| WBCnstr00042819 | |||||||||
| Construct_product | WBCnstr00000442 | ||||||||
| WBCnstr00019393 | |||||||||
| WBCnstr00042819 | |||||||||
| Antibody | WBAntibody00000626 | ||||||||
| Microarray_results (25) | |||||||||
| Expression_cluster (173) | |||||||||
| Interaction (95) | |||||||||
| Map_info | Map | I | Position | -4.45779 | Error | 0.003381 | |||
| Positive | Positive_clone | Y54E10A | Inferred_automatically | From CDS info | |||||
| From sequence, transcript, pseudogene data | |||||||||
| Pseudo_map_position | |||||||||
| Reference (21) | |||||||||
| Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||||
| Method | Gene |
