WormBase Tree Display for Gene: WBGene00000145
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| WBGene00000145 | SMap | S_parent | Sequence | F35G12 | |||||
|---|---|---|---|---|---|---|---|---|---|
| Identity | Version | 1 | |||||||
| Name | CGC_name | apc-11 | Person_evidence | WBPerson205 | |||||
| Sequence_name | F35G12.9 | ||||||||
| Molecular_name | F35G12.9 | ||||||||
| F35G12.9.1 | |||||||||
| CE00978 | |||||||||
| Other_name | CELE_F35G12.9 | Accession_evidence | NDB | BX284603 | |||||
| Public_name | apc-11 | ||||||||
| DB_info | Database | AceView | gene | 3F684 | |||||
| WormQTL | gene | WBGene00000145 | |||||||
| WormFlux | gene | WBGene00000145 | |||||||
| NDB | locus_tag | CELE_F35G12.9 | |||||||
| Panther | gene | CAEEL|WormBase=WBGene00000145|UniProtKB=Q20052 | |||||||
| family | PTHR11210 | ||||||||
| NCBI | gene | 175604 | |||||||
| RefSeq | protein | NM_065536.8 | |||||||
| SwissProt | UniProtAcc | Q20052 | |||||||
| TREEFAM | TREEFAM_ID | TF354219 | |||||||
| UniProt_GCRP | UniProtAcc | Q20052 | |||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 07 Apr 2004 11:29:20 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | apc | ||||||||
| Allele | WBVar00145492 | Inferred_automatically | From strain object: VC109 | ||||||
| WBVar00822687 | |||||||||
| WBVar00822688 | |||||||||
| WBVar00822689 | |||||||||
| WBVar00822690 | |||||||||
| WBVar02034155 | |||||||||
| Strain | WBStrain00035511 | ||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation (30) | |||||||||
| Contained_in_operon | CEOP3204 | ||||||||
| Ortholog (32) | |||||||||
| Paralog | WBGene00019993 | Caenorhabditis elegans | From_analysis | Panther | |||||
| WormBase-Compara | |||||||||
| WBGene00004320 | Caenorhabditis elegans | From_analysis | Panther | ||||||
| WormBase-Compara | |||||||||
| Structured_description | Concise_description | apc-11 encodes an E3 ubiquitin ligase that is orthologous to subunit 11 of the anaphase promoting complex (APC); apc-11 is required for embryonic development past the one-cell stage; APC-11 functions together with the LET-70/UBC-2 E2-conjugating enzyme: purified APC-11 and LET-70 exhibit ubiquitination activity in vitro. | Paper_evidence | WBPaper00005096 | |||||
| WBPaper00024468 | |||||||||
| Curator_confirmed | WBPerson48 | ||||||||
| WBPerson1843 | |||||||||
| Date_last_updated | 06 May 2009 00:00:00 | ||||||||
| Automated_description | Enables ubiquitin-protein transferase activity. Involved in anaphase-promoting complex-dependent catabolic process; embryo development; and meiotic chromosome segregation. Predicted to be located in nucleus. Predicted to be part of anaphase-promoting complex. Expressed in germ line. Is an ortholog of human ANAPC11 (anaphase promoting complex subunit 11). | Paper_evidence | WBPaper00065943 | ||||||
| WBPaper00067038 | |||||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS296 version of WormBase | ||||||||
| Date_last_updated | 20 Mar 2025 00:00:00 | ||||||||
| Molecular_info | Corresponding_CDS | F35G12.9 | |||||||
| Corresponding_transcript | F35G12.9.1 | ||||||||
| Other_sequence (26) | |||||||||
| Associated_feature | WBsf226552 | ||||||||
| Experimental_info | RNAi_result (11) | ||||||||
| Expr_pattern | Expr2886 | ||||||||
| Expr1020404 | |||||||||
| Expr1030077 | |||||||||
| Expr1150274 | |||||||||
| Expr2009352 | |||||||||
| Expr2027588 | |||||||||
| Drives_construct | WBCnstr00037706 | ||||||||
| Construct_product | WBCnstr00037706 | ||||||||
| Microarray_results (19) | |||||||||
| Expression_cluster (135) | |||||||||
| Interaction (171) | |||||||||
| Map_info | Map | III | Position | -3.03782 | Error | 0.003089 | |||
| Positive | Positive_clone | F35G12 | Inferred_automatically | From CDS info | |||||
| From sequence, transcript, pseudogene data | |||||||||
| Mapping_data | Multi_point | 4157 | |||||||
| Pseudo_map_position | |||||||||
| Reference | WBPaper00006387 | ||||||||
| WBPaper00006435 | |||||||||
| WBPaper00019452 | |||||||||
| WBPaper00024321 | |||||||||
| WBPaper00024468 | |||||||||
| WBPaper00027315 | |||||||||
| WBPaper00028987 | |||||||||
| WBPaper00038491 | |||||||||
| WBPaper00039858 | |||||||||
| WBPaper00055090 | |||||||||
| Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||||
| Method | Gene |
