WormBase Tree Display for Gene: HGNC:1460
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HGNC:1460 | Identity | Name | CGC_name | Camk2a | Inferred_automatically | AGR_import |
---|---|---|---|---|---|---|
Other_name (17) | ||||||
Public_name | Camk2a | |||||
DB_info | Database | HGNC | id | 1460 | ||
AGR | cURI | HGNC:1460 | ||||
EnsEMBL | ENSEMBL_geneID | ENSG00000070808 | ||||
UniProt | UniProt_AC | Q9UQM7 | ||||
OMIM | gene | 114078 | ||||
DO | id | DOID:10652 | ||||
DOID:3070 | ||||||
DOID:0081224 | ||||||
DOID:0080228 | ||||||
Species | Homo sapiens | |||||
Status | Live | |||||
Gene_info | Biotype | SO:0001217 | ||||
Ortholog | WBGene00006779 | Caenorhabditis elegans | From_analysis | Hieranoid | ||
Inparanoid | ||||||
OMA | ||||||
OrthoFinder | ||||||
OrthoInspector | ||||||
Panther | ||||||
PhylomeDB | ||||||
SonicParanoid | ||||||
Structured_description | Automated_description | The product of this gene belongs to the serine/threonine protein kinases family, and to the Ca(2+)/calmodulin-dependent protein kinases subfamily. Calcium signaling is crucial for several aspects of plasticity at glutamatergic synapses. This calcium calmodulin-dependent protein kinase is composed of four different chains: alpha, beta, gamma, and delta. The alpha chain encoded by this gene is required for hippocampal long-term potentiation (LTP) and spatial learning. In addition to its calcium-calmodulin (CaM)-dependent activity, this protein can undergo autophosphorylation, resulting in CaM-independent activity. Several transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Jun 2018] | Inferred_automatically | AGR_import |