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WormBase Tree Display for Gene: WBGene00012376

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Name Class

WBGene00012376SMapS_parentSequenceCHROMOSOME_I
IdentityVersion3
NameCGC_namenduf-7
Sequence_nameW10D5.2
Molecular_nameW10D5.2
W10D5.2.1
CE14780
W10D5.2.2
Other_namendus-7Person_evidenceWBPerson555
CELE_W10D5.2Accession_evidenceNDBBX284601
Public_namenduf-7
DB_infoDatabase (13)
SpeciesCaenorhabditis elegans
HistoryVersion_change126 May 2004 16:54:53WBPerson1971EventImportedInitial conversion from CDS class of WS125
226 Feb 2008 13:57:13WBPerson2970Name_changeCGC_namenduf-7
316 Jan 2023 18:37:21WBPerson51134Name_changeOther_namendus-7
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classnduf
Allele (33)
StrainWBStrain00003495
WBStrain00031178
RNASeq_FPKM (74)
GO_annotation (19)
Contained_in_operonCEOP1532
Ortholog (36)
Structured_descriptionConcise_descriptionW10D5.2 is orthologous to the human gene NADH-UBIQUINONE OXIDOREDUCTASE Fe-S PROTEIN 7 (NDUFS7; OMIM:601825), which when mutated leads to Leigh syndrome (OMIM:256000).Paper_evidenceWBPaper00004424
Curator_confirmedWBPerson1823
WBPerson567
Date_last_updated17 Jun 2004 00:00:00
Automated_descriptionPredicted to enable NADH dehydrogenase (ubiquinone) activity. Predicted to be involved in aerobic respiration; electron transport coupled proton transport; and mitochondrial respiratory chain complex I assembly. Predicted to be located in mitochondrion and respirasome. Predicted to be part of mitochondrial respiratory chain complex I. Expressed in intestine. Human ortholog(s) of this gene implicated in bipolar disorder; developmental disorder of mental health; and nuclear type mitochondrial complex I deficiency 3. Is an ortholog of human NDUFS7 (NADH:ubiquinone oxidoreductase core subunit S7).Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS292 version of WormBase
Date_last_updated24 Apr 2024 00:00:00
Disease_infoPotential_modelDOID:3312Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:7714)
DOID:0060037Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:7714)
DOID:0112093Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:7714)
Molecular_infoCorresponding_CDSW10D5.2
Corresponding_transcriptW10D5.2.1
W10D5.2.2
Other_sequenceMJC01862_1
ES739614.1
LSC01079_1
ZP00083
HG05459
FC540518.1
OOC03495_1
AM743559.1
XI03626
NBC01942_1
ES409631.1
Tcol_isotig05807
BM00443
MCC05633_1
Oden_isotig06056
TMC00876_1
MJ02758
DN558235.1
HBC24283_1
PPC03362_1
Acan_isotig17811
HGC03744_1
XIC01299_1
HG02151
HCC02310_1
FE918047.1
BM174635.1
CRC07260_1
BG467522.1
AS01500
AS04334
FG587378.1
Tcir_isotig10231
EW742325.1
AI239327.1
TSC07124_1
AE00489
ES562692.1
BG467622.1
BMC02441_1
DI02300
FD514431.1
Oden_isotig06057
BUC00363_1
ES413366.1
HBC09089_1
FC821091.1
ES409446.1
Oden_isotig06058
CR02035
BU088568.1
EW741990.1
NB09937
JI178556.1
JI466366.1
BM174763.1
ZPC00163_1
Acan_isotig12586
CBC02717_1
Tcol_isotig05805
MC05078
Dviv_isotig22730
CSC01768_1
DIC01874_1
Acan_isotig17591
SRC01478_1
Hbac_isotig03804
OVC02642_1
WBC01994_1
CGC01194_1
CRC00638_1
HC03954
CK850677.1
NAC00333_1
Acan_isotig17671
HBC03384_1
SR00788
DA05401
BE491812.1
CJC02530_1
FC817216.1
AYC01573_1
AI670464.1
AW562076.1
TDC02364_1
Name_isotig02916
CK855361.1
BU087966.1
Tcol_isotig05806
ES742512.1
EX910494.1
BU089075.1
CR10182
FC543718.1
EX914049.1
ES412654.1
ACC02649_1
ASC01045_1
FC821707.1
DAC01674_1
FE913443.1
Associated_feature (15)
Experimental_infoRNAi_result (23)
Expr_patternChronogram966
Expr6866
Expr12381
Expr1026047
Expr1035484
Expr1158621
Expr2013935
Expr2032174
Drives_constructWBCnstr00003953
WBCnstr00021000
WBCnstr00029981
Construct_productWBCnstr00029981
Microarray_results (24)
Expression_cluster (109)
Interaction (82)
Map_infoMapIPosition3.57757Error0.008816
PositivePositive_cloneW10D5Inferred_automaticallyFrom sequence, transcript, pseudogene data
Pseudo_map_position
Reference (12)
RemarkMap position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.CGC_data_submission
MethodGene