WormBase Tree Display for Gene: WBGene00012166

WBGene00012166 SMap: S_parent: Sequence: W01A8
  Identity: Version: 3
    Name: CGC_name: nuo-6 Paper_evidence: WBPaper00036109
          Person_evidence: WBPerson364
      Sequence_name: W01A8.4
      Molecular_name: W01A8.4
        W01A8.4.1
        CE32507
      Other_name: ndub-4 Person_evidence: WBPerson555
        CELE_W01A8.4 Accession_evidence: NDB BX284601
      Public_name: nuo-6
    DB_info: Database: AceView gene 1H644
        WormQTL gene WBGene00012166
        WormFlux gene WBGene00012166
        NDB locus_tag CELE_W01A8.4
        Panther gene CAEEL|WormBase=WBGene00012166|UniProtKB=Q23098
          family PTHR15469
        NCBI gene 172438
        RefSeq protein NM_059600.6
        TREEFAM TREEFAM_ID TF353901
        TrEMBL UniProtAcc Q23098
        UniProt_GCRP UniProtAcc Q23098
    Species: Caenorhabditis elegans
    History: Version_change: 1 26 May 2004 16:54:53 WBPerson1971 Event: Imported: Initial conversion from CDS class of WS125
        2 07 Jul 2010 13:18:30 WBPerson2970 Name_change: CGC_name: nuo-6
        3 16 Jan 2023 18:37:21 WBPerson51134 Name_change: Other_name: ndub-4
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: nuo
    Allele (16)
    Strain: WBStrain00026676
    RNASeq_FPKM (74)
    GO_annotation: 00080074
      00080075
      00080076
      00080077
      00080078
      00080079
      00123309
    Ortholog: WBGene00032060 Caenorhabditis briggsae From_analysis: Hillier-set
            OrthoMCL
            OMA
            Inparanoid_8
            WormBase-Compara
      WBGene00070764 Caenorhabditis remanei From_analysis: OMA
            TreeFam
            Inparanoid_8
            WormBase-Compara
      WBGene00154372 Caenorhabditis brenneri From_analysis: TreeFam
            WormBase-Compara
      WBGene00122197 Caenorhabditis japonica From_analysis: OMA
            TreeFam
            Inparanoid_8
            WormBase-Compara
      WBGene00150111 Caenorhabditis brenneri From_analysis: OMA
            TreeFam
            Inparanoid_8
            WormBase-Compara
      WBGene00226354 Brugia malayi From_analysis: WormBase-Compara
      CBOVI.g9641 Caenorhabditis bovis From_analysis: WormBase-Compara
      CSP21.g3425 Caenorhabditis parvicauda From_analysis: WormBase-Compara
      CSP26.g4514 Caenorhabditis zanzibari From_analysis: WormBase-Compara
      CSP28.g13065 Caenorhabditis panamensis From_analysis: WormBase-Compara
      CSP29.g10723 Caenorhabditis becei From_analysis: WormBase-Compara
      CSP31.g111 Caenorhabditis uteleia From_analysis: WormBase-Compara
      CSP32.g15425 Caenorhabditis sulstoni From_analysis: WormBase-Compara
      CSP38.g1743 Caenorhabditis quiockensis From_analysis: WormBase-Compara
      CSP39.g29134 Caenorhabditis waitukubuli From_analysis: WormBase-Compara
      CSP40.g17937 Caenorhabditis tribulationis From_analysis: WormBase-Compara
      Cang_2012_03_13_00303.g8851 Caenorhabditis angaria From_analysis: WormBase-Compara
      Cni-nuo-6 Caenorhabditis nigoni From_analysis: WormBase-Compara
      Csp11.Scaffold542.g3405 Caenorhabditis tropicalis From_analysis: WormBase-Compara
      Csp5_scaffold_01482.g21186 Caenorhabditis sinica From_analysis: WormBase-Compara
      FL83_07590 Caenorhabditis latens From_analysis: WormBase-Compara
      GCK72_000243 Caenorhabditis remanei From_analysis: WormBase-Compara
      OTIPU.nOt.2.0.1.g14866 Oscheius tipulae From_analysis: WormBase-Compara
      Pan_g17468 Panagrellus redivivus From_analysis: WormBase-Compara
      Sp34_10081800 Caenorhabditis inopinata From_analysis: WormBase-Compara
      chrI_pilon.g1299 Caenorhabditis elegans From_analysis: WormBase-Compara
      WBGene00248527 Onchocerca volvulus From_analysis: WormBase-Compara
      WBGene00304742 Pristionchus pacificus From_analysis: WormBase-Compara
      WBGene00263627 Strongyloides ratti From_analysis: WormBase-Compara
      WBGene00292457 Trichuris muris From_analysis: WormBase-Compara
      FB:FBgn0033961 Drosophila melanogaster From_analysis: EnsEMBL-Compara
            Hieranoid
            OrthoFinder
            Panther
      ZFIN:ZDB-GENE-040426-1973 Danio rerio From_analysis: EnsEMBL-Compara
            Hieranoid
            OrthoFinder
            Panther
      HGNC:7699 Homo sapiens From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OrthoFinder
            OrthoInspector
            Panther
            PhylomeDB
            SonicParanoid
      MGI:1915444 Mus musculus From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OrthoFinder
            Panther
            PhylomeDB
      MGI:3782046 Mus musculus From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OrthoFinder
            Panther
            PhylomeDB
      RGD:1307072 Rattus norvegicus From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OrthoFinder
            Panther
            PhylomeDB
      RGD:1560088 Rattus norvegicus From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OrthoFinder
            Panther
            PhylomeDB
      RGD:1560413 Rattus norvegicus From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OrthoFinder
            Panther
      RGD:1596079 Rattus norvegicus From_analysis: EnsEMBL-Compara
            Hieranoid
            OrthoFinder
      RGD:2319146 Rattus norvegicus From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OrthoFinder
            Panther
            PhylomeDB
      RGD:9202400 Rattus norvegicus From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OrthoFinder
            Panther
            PhylomeDB
      RGD:40961805 Rattus norvegicus From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OrthoFinder
            Panther
            PhylomeDB
    Structured_description: Concise_description: nuo-6 encodes the C. elegans ortholog of the NDUFB4/B15 subunit of the mitochondrial NADH dehydrogenase (ubiquinone) complex (complex I). Paper_evidence: WBPaper00036109
          Curator_confirmed: WBPerson1843
          Date_last_updated: 25 Mar 2013 00:00:00
      Automated_description: Predicted to be located in mitochondrial inner membrane. Predicted to be part of respiratory chain complex I. Expressed in body wall musculature; germ line; gonad; and hypodermis. Is an ortholog of human NDUFB4 (NADH:ubiquinone oxidoreductase subunit B4). Paper_evidence: WBPaper00065943
            WBPaper00067038
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS296 version of WormBase
          Date_last_updated: 20 Mar 2025 00:00:00
  Molecular_info: Corresponding_CDS: W01A8.4
    Corresponding_CDS_history: W01A8.4:wp90
    Corresponding_transcript: W01A8.4.1
    Other_sequence (89)
    Associated_feature: WBsf649280
      WBsf219672
  Experimental_info: RNAi_result (28)
    Expr_pattern: Expr9086
      Expr1016520
      Expr1035381
      Expr1158040
      Expr2014532
      Expr2032771
    Drives_construct: WBCnstr00013711
      WBCnstr00030096
    Construct_product: WBCnstr00013711
      WBCnstr00030096
    Regulate_expr_cluster: WBPaper00045263:nuo-6(qm200)_downregulated
      WBPaper00045263:nuo-6(qm200)_upregulated
      WBPaper00045263:ProLongevity-mtROS_downregulated
      WBPaper00045263:ProLongevity-mtROS_upregulated
      WBPaper00053810:nuo-6(qm200)_downregulated
      WBPaper00053810:nuo-6(qm200)_upregulated
      WBPaper00055941:nuo-6(qm200);atfs-1(gk3094)_downregulated
      WBPaper00055941:nuo-6(qm200);atfs-1(gk3094)_upregulated
      WBPaper00055941:nuo-6(qm200)_downregulated
      WBPaper00055941:nuo-6(qm200)_upregulated
    Microarray_results (17)
    Expression_cluster (106)
    Interaction (70)
    WBProcess: WBbiopr:00000001
  Map_info: Map: I Position: 1.69904 Error: 0.003103
    Positive: Positive_clone: W01A8 Inferred_automatically: From sequence, transcript, pseudogene data
    Pseudo_map_position
  Reference (47)
  Remark: Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. CGC_data_submission
  Method: Gene