WormBase Tree Display for Gene: WBGene00009192

WBGene00009192 SMap: S_parent: Sequence: F27E5
  Identity: Version: 2
    Name: CGC_name: asah-2 Person_evidence: WBPerson237
      Sequence_name: F27E5.1
      Molecular_name: F27E5.1
        F27E5.1.1
        CE01562
      Other_name: CELE_F27E5.1 Accession_evidence: NDB BX284602
      Public_name: asah-2
    DB_info: Database (13)
    Species: Caenorhabditis elegans
    History: Version_change: 1 26 May 2004 16:54:49 WBPerson1971 Event: Imported: Initial conversion from CDS class of WS125
        2 25 Oct 2016 11:59:12 WBPerson2970 Name_change: CGC_name: asah-2
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: asah
    Allele (30)
    Strain: WBStrain00031495
    RNASeq_FPKM (74)
    GO_annotation: 00051990
      00051991
      00051992
      00051993
      00051994
      00051995
      00111734
      00111735
      00111736
    Ortholog: WBGene00071613 Caenorhabditis remanei From_analysis: OMA
            TreeFam
            Inparanoid_8
            WormBase-Compara
      WBGene00024190 Caenorhabditis briggsae From_analysis: Hillier-set
            OrthoMCL
            OMA
            Inparanoid_8
            WormBase-Compara
      WBGene00155195 Caenorhabditis brenneri From_analysis: OMA
            TreeFam
            Inparanoid_8
            WormBase-Compara
      WBGene00158225 Caenorhabditis brenneri From_analysis: OMA
            TreeFam
            Inparanoid_8
            WormBase-Compara
      WBGene00137260 Caenorhabditis japonica From_analysis: TreeFam
            Inparanoid_8
            WormBase-Compara
      WBGene00101417 Pristionchus pacificus From_analysis: OMA
            WormBase-Compara
      WBGene00101357 Pristionchus pacificus From_analysis: OMA
            WormBase-Compara
      WBGene00227104 Brugia malayi From_analysis: WormBase-Compara
      CBOVI.g7499 Caenorhabditis bovis From_analysis: WormBase-Compara
      CSP26.g18245 Caenorhabditis zanzibari From_analysis: WormBase-Compara
      CSP28.g321 Caenorhabditis panamensis From_analysis: WormBase-Compara
      CSP29.g12670 Caenorhabditis becei From_analysis: WormBase-Compara
      CSP31.g27415 Caenorhabditis uteleia From_analysis: WormBase-Compara
      CSP32.g7566 Caenorhabditis sulstoni From_analysis: WormBase-Compara
      CSP38.g9426 Caenorhabditis quiockensis From_analysis: WormBase-Compara
      CSP39.g6394 Caenorhabditis waitukubuli From_analysis: WormBase-Compara
      CSP40.g6728 Caenorhabditis tribulationis From_analysis: WormBase-Compara
      Cang_2012_03_13_00760.g13945 Caenorhabditis angaria From_analysis: WormBase-Compara
      Cni-F27E5.1 Caenorhabditis nigoni From_analysis: WormBase-Compara
      Csp11.Scaffold563.g3971 Caenorhabditis tropicalis From_analysis: WormBase-Compara
      Csp5_scaffold_03341.g29867 Caenorhabditis sinica From_analysis: WormBase-Compara
      FL83_05482 Caenorhabditis latens From_analysis: WormBase-Compara
      GCK72_004307 Caenorhabditis remanei From_analysis: WormBase-Compara
      OTIPU.nOt.2.0.1.g00581 Oscheius tipulae From_analysis: WormBase-Compara
      Pan_g2058 Panagrellus redivivus From_analysis: WormBase-Compara
      Sp34_20210500 Caenorhabditis inopinata From_analysis: WormBase-Compara
      chrII_pilon.g5671 Caenorhabditis elegans From_analysis: WormBase-Compara
      WBGene00244681 Onchocerca volvulus From_analysis: WormBase-Compara
      WBGene00093835 Pristionchus pacificus From_analysis: WormBase-Compara
      WBGene00265066 Strongyloides ratti From_analysis: WormBase-Compara
      ZFIN:ZDB-GENE-040426-1512 Danio rerio From_analysis: EnsEMBL-Compara
            OrthoFinder
            Panther
            PhylomeDB
      ZFIN:ZDB-GENE-041010-191 Danio rerio From_analysis: EnsEMBL-Compara
            OrthoFinder
            Panther
            PhylomeDB
      HGNC:735 Homo sapiens From_analysis: EnsEMBL-Compara
            OMA
            OrthoFinder
            Panther
            PhylomeDB
      MGI:1277124 Mus musculus From_analysis: EnsEMBL-Compara
            OMA
            OrthoFinder
            Panther
            PhylomeDB
      RGD:621568 Rattus norvegicus From_analysis: EnsEMBL-Compara
            OMA
            OrthoFinder
            Panther
            PhylomeDB
    Paralog: WBGene00010769 Caenorhabditis elegans From_analysis: Panther
            WormBase-Compara
      WBGene00021917 Caenorhabditis elegans From_analysis: TreeFam
            Panther
            WormBase-Compara
    Structured_description: Automated_description: Predicted to enable N-acylsphingosine amidohydrolase activity. Predicted to be involved in fatty acid metabolic process and sphingolipid metabolic process. Predicted to be located in lysosome. Human ortholog(s) of this gene implicated in Farber lipogranulomatosis; sphingolipidosis; and spinal muscular atrophy with progressive myoclonic epilepsy. Is an ortholog of human ASAH1 (N-acylsphingosine amidohydrolase 1). Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS292 version of WormBase
          Date_last_updated: 24 Apr 2024 00:00:00
  Disease_info: Potential_model: DOID:0111527 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:735)
      DOID:1927 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:735)
      DOID:0050464 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:735)
  Molecular_info: Corresponding_CDS: F27E5.1
    Corresponding_transcript: F27E5.1.1
    Other_sequence (13)
    Associated_feature: WBsf221969
      WBsf221970
      WBsf221971
  Experimental_info: RNAi_result: WBRNAi00045755 Inferred_automatically: RNAi_primary
      WBRNAi00031502 Inferred_automatically: RNAi_primary
    Expr_pattern: Expr1875
      Expr1876
      Expr1010559
      Expr1149664
      Expr2009442
      Expr2027679
    Drives_construct: WBCnstr00032384
    Construct_product: WBCnstr00032384
    Antibody: WBAntibody00000505
    Microarray_results (19)
    Expression_cluster (248)
    Interaction (164)
  Map_info: Map: II Position: 1.97775
    Positive: Positive_clone: F27E5 Inferred_automatically: From sequence, transcript, pseudogene data
    Pseudo_map_position
  Reference: WBPaper00032243
    WBPaper00038491
    WBPaper00042257
    WBPaper00055090
    WBPaper00062863
  Remark: Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. CGC_data_submission
  Method: Gene