WormBase Tree Display for Gene: WBGene00004347
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WBGene00004347 | SMap | S_parent | Sequence | Y38E10A | |||||
---|---|---|---|---|---|---|---|---|---|
Identity | Version | 3 | |||||||
Name | CGC_name | rgs-4 | Person_evidence | WBPerson330 | |||||
Sequence_name | Y38E10A.21 | ||||||||
Molecular_name | Y38E10A.21a | ||||||||
Y38E10A.21a.1 | |||||||||
CE46667 | |||||||||
Y38E10A.21b | |||||||||
CE46711 | |||||||||
Y38E10A.21c | |||||||||
CE52991 | |||||||||
Y38E10A.21d | |||||||||
CE53887 | |||||||||
Y38E10A.21b.1 | |||||||||
Y38E10A.21c.1 | |||||||||
Y38E10A.21d.1 | |||||||||
Other_name | CELE_Y38E10A.21 | Accession_evidence | NDB | BX284602 | |||||
Public_name | rgs-4 | ||||||||
DB_info | Database | AceView | gene | 2M957 | |||||
WormQTL | gene | WBGene00004347 | |||||||
WormFlux | gene | WBGene00004347 | |||||||
NDB | locus_tag | CELE_Y38E10A.21 | |||||||
Panther | gene | CAEEL|WormBase=WBGene00004347|UniProtKB=H2KMK7 | |||||||
family | PTHR10845 | ||||||||
NCBI | gene | 189666 | |||||||
RefSeq | protein | NM_001381631.1 | |||||||
NM_001377886.2 | |||||||||
NM_001267421.4 | |||||||||
NM_001373807.2 | |||||||||
TrEMBL | UniProtAcc | H2KMK5 | |||||||
A0A5S9MNH1 | |||||||||
A0A486WXG8 | |||||||||
H2KMK7 | |||||||||
UniProt_GCRP | UniProtAcc | A0A5S9MNH1 | |||||||
Species | Caenorhabditis elegans | ||||||||
History | Version_change | 1 | 07 Apr 2004 11:29:35 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
2 | 03 Dec 2004 16:28:54 | WBPerson2970 | Event | Acquires_merge | WBGene00012599 | ||||
3 | 21 Nov 2019 16:12:41 | WBPerson4025 | Event | Acquires_merge | WBGene00012598 | ||||
Acquires_merge | WBGene00012599 | ||||||||
WBGene00012598 | |||||||||
Status | Live | ||||||||
Gene_info | Biotype | SO:0001217 | |||||||
Gene_class | rgs | ||||||||
Allele (540) | |||||||||
Strain | WBStrain00026366 | ||||||||
WBStrain00031678 | |||||||||
RNASeq_FPKM (74) | |||||||||
Ortholog (31) | |||||||||
Paralog (12) | |||||||||
Structured_description | Concise_description | rgs-4 encodes a regulator of G protein signaling; by homology, RGS-4 is predicted to function as a GTPase-activating protein that binds G protein alpha subunits and negatively regulates heterotrimeric G protein signaling; loss of rgs-4 activity via RNAi or a deletion mutation results in no obvious defects, and likewise, rgs-4 overexpression has no measurable effect on egg-laying behavior, locomotion, or viability; the RGS-4 expression pattern has not yet been reported. | Paper_evidence | WBPaper00004281 | |||||
WBPaper00024480 | |||||||||
Curator_confirmed | WBPerson1843 | ||||||||
Date_last_updated | 07 Feb 2005 00:00:00 | ||||||||
Automated_description | Enriched in head mesodermal cell; neurons; and ventral nerve cord based on microarray; tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including mter-4; etr-1; and isp-1 based on tiling array; microarray; and RNA-seq studies. Is affected by thirteen chemicals including stavudine; Psoralens; and allantoin based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: RGS, subdomain 2; Regulator of G protein signaling domain; RGS domain superfamily; and RGS domain. | Paper_evidence | WBPaper00065943 | ||||||
Curator_confirmed | WBPerson324 | ||||||||
WBPerson37462 | |||||||||
Inferred_automatically | This description was generated automatically by a script based on data from the WS292 version of WormBase | ||||||||
Date_last_updated | 24 Apr 2024 00:00:00 | ||||||||
Molecular_info | Corresponding_CDS | Y38E10A.21a | |||||||
Y38E10A.21b | |||||||||
Y38E10A.21c | |||||||||
Y38E10A.21d | |||||||||
Corresponding_CDS_history | Y38E10A.21:wp229 | ||||||||
Y38E10A.21a:wp274 | |||||||||
Corresponding_transcript | Y38E10A.21a.1 | ||||||||
Y38E10A.21b.1 | |||||||||
Y38E10A.21c.1 | |||||||||
Y38E10A.21d.1 | |||||||||
Other_sequence (36) | |||||||||
Associated_feature (12) | |||||||||
Experimental_info | RNAi_result | WBRNAi00020288 | Inferred_automatically | RNAi_primary | |||||
WBRNAi00056020 | Inferred_automatically | RNAi_primary | |||||||
WBRNAi00020287 | Inferred_automatically | RNAi_primary | |||||||
WBRNAi00056021 | Inferred_automatically | RNAi_primary | |||||||
Expr_pattern | Chronogram882 | ||||||||
Chronogram1470 | |||||||||
Expr1022441 | |||||||||
Expr1027927 | |||||||||
Expr1032165 | |||||||||
Expr1159539 | |||||||||
Expr1159540 | |||||||||
Expr2007301 | |||||||||
Expr2015327 | |||||||||
Expr2033561 | |||||||||
Drives_construct | WBCnstr00004337 | ||||||||
Microarray_results (35) | |||||||||
Expression_cluster (132) | |||||||||
Map_info | Map | II | Position | 10.6551 | Error | 0.037636 | |||
Positive | Positive_clone | Y38E10A | Inferred_automatically | From sequence, transcript, pseudogene data | |||||
Mapping_data | Multi_point | 4624 | |||||||
4673 | |||||||||
5028 | |||||||||
Pseudo_map_position | |||||||||
Reference | WBPaper00004281 | ||||||||
WBPaper00055090 | |||||||||
Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||||
Method | Gene |