WormBase Tree Display for Gene: WBGene00000367

WBGene00000367 SMap: S_parent: Sequence: CHROMOSOME_X
  Identity: Version: 1
    Name: CGC_name: cca-1 Person_evidence: WBPerson604
      Sequence_name: C54D2.5
      Molecular_name (17)
      Other_name: CELE_C54D2.5 Accession_evidence: NDB BX284606
      Public_name: cca-1
    DB_info: Database (11)
    Species: Caenorhabditis elegans
    History: Version_change: 1 07 Apr 2004 11:29:20 WBPerson1971 Event: Imported: Initial conversion from geneace
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: cca
    Allele: WBVar00000099 Inferred_automatically: From strain object: JD21
      WBVar00094445 Inferred_automatically: From strain object: RB2487
      WBVar00145485 Inferred_automatically: From strain object: VC39
      WBVar01500067
      WBVar01163738
      WBVar00509435
      WBVar01163739
      WBVar00509436
      WBVar01163740
      WBVar00509437
      WBVar01163741
      WBVar00509438
      WBVar00509439
      WBVar01163742
      WBVar00509440
      WBVar01490319
      WBVar01163743
      WBVar00509441
      WBVar01163744
      WBVar00509442
      WBVar01163745
      WBVar00509443
      WBVar01163746
      WBVar01163747
      WBVar00509444
      WBVar01163748
      WBVar00509445
      WBVar01163749
      WBVar00509446
      WBVar00509447
      WBVar01163750
      WBVar01163751
      WBVar00509448
      WBVar02064851
      WBVar00509449
      WBVar01163752
      WBVar00315945
      WBVar01825241
      WBVar02064852
      WBVar01163753
      WBVar00509450
      WBVar01163754
      WBVar00509451
      WBVar02064853
      WBVar02064854
      WBVar00509452
      WBVar01163755
      WBVar01163756
      WBVar00509453
      WBVar02064855
      WBVar00509454
      WBVar01163757
      WBVar02064856
      WBVar01550573
      WBVar02064857
      WBVar01163758
      WBVar00509455
      WBVar01550574
      WBVar02064858
      WBVar01163759
      WBVar00509456
      WBVar01550575
      WBVar01163760
      WBVar00509457
      WBVar01163761
      WBVar00509458
      WBVar00509459
      WBVar01163762
      WBVar01883860
      WBVar00509460
      WBVar01163763
      WBVar01163764
      WBVar00509461
      WBVar01883861
      WBVar01883862
      WBVar01163765
      WBVar01495861
      WBVar00509462
      WBVar01883863
      WBVar01163766
      WBVar00509463
      WBVar00509464
      WBVar01883864
      WBVar01163767
      WBVar00509465
      WBVar01163768
      WBVar01883865
      WBVar01163769
      WBVar00509466
      WBVar01883866
      WBVar01883867
      WBVar00509467
      WBVar01163770
      WBVar02147045
      WBVar01883868
      WBVar01163771
      WBVar00509468
      WBVar01883869
      WBVar01163773
      WBVar00509469
      WBVar01163774
      WBVar01883870
      WBVar00509470
      WBVar01163775
      WBVar00509471
      WBVar01945684
      WBVar01883871
      WBVar00509472
      WBVar01883872
      WBVar01163776
      WBVar00509473
      WBVar01883873
      WBVar01163777
      WBVar01883874
      WBVar01163778
      WBVar00509474
      WBVar01883875
      WBVar00509475
      WBVar01163779
      WBVar02139642
      WBVar02139643
      WBVar00509476
      WBVar01163780
      WBVar02139644
      WBVar01163781
      WBVar00509477
      WBVar00509478
      WBVar02139645
      WBVar01163782
      WBVar02139646
      WBVar01163783
      WBVar00509479
      WBVar01163784
      WBVar02139647
      WBVar00509480
      WBVar01163785
      WBVar00509481
      WBVar02139648
      WBVar02139649
      WBVar00509482
      WBVar00050936
      WBVar01163786
      WBVar00509483
      WBVar01163787
      WBVar00050941
      WBVar00509484
      WBVar01163788
      WBVar00509485
      WBVar01499933
      WBVar01163789
      WBVar02080346
      WBVar01499934
      WBVar01163790
      WBVar00050946
      WBVar01163791
      WBVar01163792
      WBVar01163793
      WBVar00050951
      WBVar01163794
      WBVar01163795
      WBVar01163796
      WBVar00050956
      WBVar01163797
      WBVar01163798
      WBVar00050961
      WBVar01163799
      WBVar01163800
      WBVar01163801
      WBVar01163802
      WBVar00050966
      WBVar01163803
      WBVar01163804
      WBVar01163805
      WBVar00050971
      WBVar01163806
      WBVar01163622
      WBVar01163807
      WBVar00142685
      WBVar01163623
      WBVar00050976
      WBVar01163808
      WBVar01163624
      WBVar01163809
      WBVar01487256
      WBVar01163810
      WBVar00050981
      WBVar01163625
      WBVar01487257
      WBVar01163626
      WBVar01163811
      WBVar01816077
      WBVar01163627
      WBVar01163812
      WBVar00050986
      WBVar01816078
      WBVar01816079
      WBVar01163628
      WBVar01163813
      WBVar00050991
      WBVar01163814
      WBVar01816080
      WBVar01163629
      WBVar01163815
      WBVar01816081
      WBVar01163630
      WBVar01163631
      WBVar01816082
      WBVar01163816
      WBVar00050996
      WBVar01816083
      WBVar01163632
      WBVar01163817
      WBVar01816084
      WBVar01163633
      WBVar01163818
      WBVar01816085
      WBVar00051001
      WBVar01163819
      WBVar01163634
      WBVar01782312
      WBVar01816086
      WBVar01163635
      WBVar01816087
      WBVar01782313
      WBVar01163636
      WBVar01499781
      WBVar01497756
      WBVar01816088
      WBVar00051006
      WBVar01163637
      WBVar01816089
      WBVar01163638
      WBVar01163639
      WBVar01816090
      WBVar00051011
      WBVar01163640
      WBVar01163641
      WBVar01163642
      WBVar00051016
      WBVar01163643
      WBVar01526949
      WBVar02046578
      WBVar01163644
      WBVar01526950
      WBVar02046579
      WBVar01163645
      WBVar01163646
      WBVar01526951
      WBVar01526952
      WBVar01834981
      WBVar01163647
      WBVar01526953
      WBVar01163648
      WBVar00051026
      WBVar01163649
      WBVar01526954
      WBVar01526955
      WBVar01163650
      WBVar01163651
      WBVar00051031
      WBVar02032760
      WBVar01163652
      WBVar01491148
      WBVar01163653
      WBVar00233671
      WBVar01163654
      WBVar00051036
      WBVar00233672
      WBVar00236432
      WBVar00236433
      WBVar02076299
      WBVar01163655
      WBVar01927426
      WBVar00236434
      WBVar01163656
      WBVar01927427
      WBVar00236435
      WBVar01820354
      WBVar00051041
      WBVar01163657
      WBVar01820355
      WBVar01927428
      WBVar01163658
      WBVar01163659
      WBVar01927429
      WBVar02045092
      WBVar01820356
      WBVar00051046
      WBVar01163660
      WBVar02045093
      WBVar01820357
      WBVar01927430
      WBVar02045094
      WBVar01163661
      WBVar01820358
      WBVar01927431
      WBVar02045095
      WBVar01163662
      WBVar01927432
      WBVar01820359
      WBVar01163663
      WBVar00051051
      WBVar01927433
      WBVar02045096
      WBVar01163664
      WBVar01927434
      WBVar00315337
      WBVar01163665
      WBVar01927435
      WBVar00315338
      WBVar01927436
      WBVar01163666
      WBVar00315339
      WBVar00051056
      WBVar00315340
      WBVar01163667
      WBVar01927437
      WBVar01163668
      WBVar00243841
      WBVar01927438
      WBVar00051061
      WBVar01927439
      WBVar01163669
      WBVar01163670
      WBVar01163671
      WBVar00051066
      WBVar01163672
      WBVar01163673
      WBVar02051073
      WBVar00051071
      WBVar01493746
      WBVar01163674
      WBVar01163675
      WBVar01163676
      WBVar02056472
      WBVar01163677
      WBVar00099159
      WBVar00099161
      WBVar02056473
      WBVar01163678
      WBVar00051081
      WBVar02056474
      WBVar01163679
      WBVar00099163
      WBVar01163680
      WBVar00051086
      WBVar01499642
      WBVar01835755
      WBVar01163681
      WBVar00051091
      WBVar01163682
      WBVar01500012
      WBVar01163683
      WBVar01500013
      WBVar00080770
      WBVar01163684
      WBVar01163685
      WBVar02116496
      WBVar00080771
      WBVar00051096
      WBVar01163686
      WBVar00080775
      WBVar02116497
      WBVar02116498
      WBVar00080776
      WBVar01163687
      WBVar00080777
      WBVar00051101
      WBVar01163688
      WBVar00080779
      WBVar01163689
      WBVar01163690
      WBVar00080780
      WBVar00051106
      WBVar00080781
      WBVar01163691
      WBVar00080783
      WBVar01163692
      WBVar01163693
      WBVar00080784
      WBVar00051111
      WBVar01163694
      WBVar00080788
      WBVar00080790
      WBVar01163695
      WBVar00080791
      WBVar01163696
      WBVar00080792
      WBVar01849318
      WBVar01163697
      WBVar00051116
      WBVar01163698
      WBVar00080793
      WBVar01849319
      WBVar00080796
      WBVar00300517
      WBVar01163699
      WBVar01849320
      WBVar01163700
      WBVar00300518
      WBVar00080797
      WBVar00051121
      WBVar01849321
      WBVar01849322
      WBVar00080798
      WBVar01163701
      WBVar01495982
      WBVar00080800
      WBVar01163702
      WBVar01163703
      WBVar00080804
      WBVar00051126
      WBVar00080805
      WBVar01163704
      WBVar00051131
      WBVar01163705
      WBVar00080809
      WBVar01601973
      WBVar01163706
      WBVar00080814
      WBVar01163707
      WBVar00080815
      WBVar00259065
      WBVar01163708
      WBVar00080820
      WBVar00051136
      WBVar01163709
      WBVar00080821
      WBVar00080824
      WBVar01163710
      WBVar01163711
      WBVar00080825
      WBVar01163712
      WBVar01163713
      WBVar01163714
      WBVar01469868
      WBVar01980981
      WBVar00051146
      WBVar01163715
      WBVar01469869
      WBVar01980982
      WBVar01469870
      WBVar01163716
      WBVar00051151
      WBVar02151216
      WBVar01163717
      WBVar01469871
      WBVar01469872
      WBVar01163718
      WBVar00051156
      WBVar01469873
      WBVar01163719
      WBVar01163720
      WBVar00051161
      WBVar01163721
      WBVar01163722
      WBVar00051166
      WBVar01163723
      WBVar01163724
      WBVar00509422
      WBVar01163725
      WBVar01163726
      WBVar00509423
      WBVar01163727
      WBVar00509424
      WBVar01163728
      WBVar00509425
      WBVar02083416
      WBVar01163729
      WBVar00509426
      WBVar01163730
      WBVar00509427
      WBVar01163731
      WBVar00509428
      WBVar00509429
      WBVar01163732
      WBVar00509430
      WBVar01163733
      WBVar00509431
      WBVar01163734
      WBVar00509432
      WBVar01498407
      WBVar01498960
      WBVar01163735
      WBVar01163736
      WBVar00509433
      WBVar01163737
      WBVar00509434
    Strain: WBStrain00035024
      WBStrain00035026
      WBStrain00002849
      WBStrain00022216
      WBStrain00033162
      WBStrain00035498
    RNASeq_FPKM (74)
    GO_annotation (28)
    Ortholog (45)
    Paralog: WBGene00001187 Caenorhabditis elegans From_analysis: WormBase-Compara
      WBGene00003558 Caenorhabditis elegans From_analysis: WormBase-Compara
      WBGene00006742 Caenorhabditis elegans From_analysis: WormBase-Compara
      WBGene00006809 Caenorhabditis elegans From_analysis: WormBase-Compara
      WBGene00008911 Caenorhabditis elegans From_analysis: WormBase-Compara
    Structured_description: Concise_description: cca-1 encodes a calcium channel alpha subunit that is homologous to vertebrate T-type calcium channel alpha 1 subunits; CCA-1 is required for regulation of pharyngeal pumping, specifically for the efficient initiation of action potentials in the pharynx in response to excitatory inputs; a CCA-1::GFP fusion protein is expressed strongly in pharyngeal muscle as well as in many neurons, including particular subsets of neurons in the head, pharynx, ventral nerve cord, and anal ganglia. Paper_evidence: WBPaper00025209
            WBPaper00025210
          Curator_confirmed: WBPerson480
            WBPerson1843
          Date_last_updated: 18 Oct 2006 00:00:00
      Automated_description: Predicted to enable low voltage-gated calcium channel activity. Involved in membrane depolarization; positive regulation of action potential; and regulation of nematode pharyngeal pumping. Predicted to be located in neuron projection. Predicted to be part of voltage-gated sodium channel complex. Expressed in several structures, including alimentary muscle; distal tip cell; pharyngeal neurons; serotonergic neurons; and ventral nerve cord. Human ortholog(s) of this gene implicated in several diseases, including cerebellar ataxia type 42; childhood absence epilepsy; and primary hyperaldosteronism. Is an ortholog of human CACNA1I (calcium voltage-gated channel subunit alpha1 I). Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS292 version of WormBase
          Date_last_updated: 24 Apr 2024 00:00:00
  Disease_info: Potential_model: DOID:446 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:1395)
      DOID:1825 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:1395)
      DOID:0111742 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:1394)
      DOID:5419 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:1396)
  Molecular_info: Corresponding_CDS: C54D2.5a
      C54D2.5c
      C54D2.5d
      C54D2.5e
      C54D2.5g
    Corresponding_CDS_history: C54D2.5b:wp170
      C54D2.5f:wp245
    Corresponding_transcript: C54D2.5a.1
      C54D2.5a.2
      C54D2.5a.3
      C54D2.5c.1
      C54D2.5d.1
      C54D2.5e.1
      C54D2.5g.1
    Other_sequence (29)
    Associated_feature (24)
  Experimental_info: RNAi_result: WBRNAi00012391 Inferred_automatically: RNAi_primary
      WBRNAi00043146 Inferred_automatically: RNAi_primary
    Expr_pattern (12)
    Drives_construct: WBCnstr00003371
      WBCnstr00004844
      WBCnstr00004846
      WBCnstr00011900
    Microarray_results (41)
    Expression_cluster (144)
    Interaction (22)
  Map_info: Map: X Position: -1.05786 Error: 0.020226
    Positive: Positive_clone: C54D2 Inferred_automatically: From sequence, transcript, pseudogene data
    Mapping_data: Multi_point: 4178
        4653
        4766
    Pseudo_map_position
  Reference (39)
  Remark: AF368920 contains the experimentally derived cDNA sequence. It differs in several regards from the sequence predicted from analysis of cosmid C54D2 (product 5).
    Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. CGC_data_submission
  Method: Gene