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WormBase Tree Display for GO_term: GO:0008518

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Name Class

GO:0008518Namefolate:monoatomic anion antiporter activity
DefinitionEnables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: Folate derivative (out) + anion (in) = folate derivative (in) + anion (out). The Reduced Folate Carrier (RCF(SLC19A1) acts by an antiport mechanism. RCF carries several folate derivatives: MTX, PMX, ratitrexed, pralatrexate, 5-methyl THF, and 5-formyl THF.
SynonymBroadfolate:anion antiporter activity
Relatedreduced folate carrier activity
reduced folate transmembrane transporter activity
reduced folate transporter
StatusValid
TypeMolecular_function
ParentInstance_ofGO:0008509
GO:0008517
GO:0015297
GO:0022853
Attributes_ofMotifINTERPRO:IPR028339
IndexAncestor (39)
VersionGene Ontology releases/2024-03-28