WormBase Tree Display for GO_term: GO:0000184

GO:0000184 Name: nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
  Definition: The nonsense-mediated decay pathway for nuclear-transcribed mRNAs degrades mRNAs in which an amino-acid codon has changed to a nonsense codon; this prevents the translation of such mRNAs into truncated, and potentially harmful, proteins.
  Synonym: Exact: mRNA breakdown, nonsense-mediated decay
      mRNA catabolic process, nonsense-mediated
      mRNA catabolism, nonsense-mediated
      mRNA degradation, nonsense-mediated decay
      nonsense-mediated mRNA decay
      nuclear mRNA catabolic process, nonsense-mediated decay
  Status: Valid
  Type: Biological_process
  Child: Instance: GO:0070478
      GO:0070479
  Parent: Instance_of: GO:0000956
  Attributes_of: Motif: INTERPRO:IPR018999
      INTERPRO:IPR019354
      INTERPRO:IPR031559
      INTERPRO:IPR039177
      INTERPRO:IPR039414
      INTERPRO:IPR039722
      INTERPRO:IPR039762
      INTERPRO:IPR044099
    Index: Ancestor (31)
      Descendant: GO:0070478
        GO:0070479
    GO_annotation (88)
  Version: Gene Ontology releases/2025-03-16