WormBase Tree Display for Expr_pattern: Expr8718
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Expr8718 | Expression_of | Gene | WBGene00016961 | |
---|---|---|---|---|
Reflects_endogenous_expression_of | WBGene00016961 | |||
Expression_data | Life_stage | WBls:0000024 | ||
WBls:0000003 | ||||
WBls:0000038 | ||||
WBls:0000027 | ||||
WBls:0000035 | ||||
WBls:0000041 | ||||
Anatomy_term | WBbt:0003681 | Certain | ||
WBbt:0005175 | Certain | |||
WBbt:0005319 | Certain | |||
WBbt:0005733 | Certain | |||
WBbt:0005772 | Certain | |||
WBbt:0006748 | Certain | |||
GO_term | GO:0010008 | |||
Subcellular_localization | In embryo, CeVPS-32 immunoreactivity was detected in a diffuse cytosolic pattern with a punctiform component characteristic of vesicular localisation. To confirm that CeVPS-32 positive vesicles are endosomes authors looked for colocalization with the endosomal marker CeVPS-27/HGRS-1. Vesicles positive for both CeVPS-32 and CeVPS-27 were detected in all epithelial tissues. However, only a subset (30%, n=606) of vesicles is positive for both markers suggesting that the presence of CeVPS-27 and/or CeVPS-32 correspond to distinct stages of endosomal maturation. | |||
Type | Antibody | |||
Pattern (3) | ||||
Picture | WBPicture0000011968 | |||
WBPicture0000011969 | ||||
WBPicture0000011970 | ||||
Remark | Picture: Fig 2, Fig 3. | |||
The specificity of anti-CeVPS-32 antibodies was confirmed by the almost complete extinction of the signal after inactivation of Cevps-32 by RNA interference and in the Cevps-32(ok1355) null mutant. | ||||
Reference | WBPaper00033139 | |||
Antibody_info | WBAntibody00001923 |