WormBase Tree Display for Expr_pattern: Expr744
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| Expr744 | Expression_of (2) | |
|---|---|---|
| Expression_data (2) | ||
| Type | Reporter_gene | |
| Pattern | cyp-8 protein as expression of beta-galactosidase was localized specifically in the gut cell nuclei. Expression is detected at all stages from embryo through to adult. Promoter region of Ce-CYP-8 examined with downstream coding sequence either including or excluding the NLS containing tail domain of cyp-8. This shows that non-cyclophilin tail domain directs the localization of this enzyme to the gut cell nuclei. Constructs containing promoter cyclophilin domain and tail domain exhibited nuclear localized gut staining in a non-nuclear localized vector. Animals transformed with the promoter and cyclophilin domain but lacking the NLS-rich tail domain show diffuse gut staining extending to the pharynx. | |
| Remark (2) | ||
| Reference | WBPaper00003528 | |
| Transgene | WBTransgene00029788 |
