WormBase Tree Display for Expr_pattern: Expr3677
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| Expr3677 | Expression_of (2) | |
|---|---|---|
| Expression_data (2) | ||
| Subcellular_localization | nrf-5::gfp fluorescence was concentrated at the basal membrane of the intestine. Based on its similarity to secreted lipid binding proteins and the fact that it contains an N-terminal signal sequence, NRF-5 probably is secreted. The concentration of nrf-5::gfp fluorescence at the basal membrane of the intestine suggests that NRF-5 protein is secreted from the intestine into the pseudocoelomic fluid. GFP fluorescence was not observed in the pseudocoelomic fluid itself, however one possibility is that the level of secreted nrf-5::gfp is too low to detect in this manner, particularly against the background of fluorescence from the intestine. | |
| Type | Reporter_gene | |
| Pattern | GFP fluorescence was observed throughout the entire intestine of transgenic animals expressing this nrf-5::gfp fusion. No GFP expression was observed in any other tissue. Furthermore, the nrf-5::gfp fusion rescued the Nrf and Peg phenotypes of nrf-5 mutants. | |
| Picture | WBPicture0000010915 | |
| Reference | WBPaper00026767 | |
| Transgene | WBTransgene00028810 |
