WormBase Tree Display for Expr_pattern: Expr16569

Expr16569 Expression_of: Gene: WBGene00011344
    Reflects_endogenous_expression_of: WBGene00011344
  Expression_data: Life_stage: WBls:0000024 Anatomy_term: WBbt:0005394
          WBbt:0005772
          WBbt:0005803
      WBls:0000038 Anatomy_term: WBbt:0005803
          WBbt:0005828
      WBls:0000027 Anatomy_term: WBbt:0005394
          WBbt:0005772
          WBbt:0005803
      WBls:0000035 Anatomy_term: WBbt:0004522
          WBbt:0005394
          WBbt:0006749
          WBbt:0006865
      WBls:0000041 Anatomy_term: WBbt:0003734
          WBbt:0004822
          WBbt:0005300
          WBbt:0005394
          WBbt:0005409
          WBbt:0005451
          WBbt:0005796
          WBbt:0005798
          WBbt:0005813
          WBbt:0005821
    Anatomy_term (17)
  Type: Reporter_gene
  Pattern: Confocal microscopy analyses revealed that myt-1 was mostly expressed in body wall muscles, neurons, and intestine early during development, while it was mainly expressed in muscles and neurons in adulthood. Next, we tested myt-1 expression in 11-day-old C. elegans (counting day 0 at L4 stage) and identified an increased expression in neurons and muscles compared with younger (3-day-old) animals, confirming an age-related regulation also in C. elegans. Finally, because the initial screening was based on genes induced when nutrients are reduced, we tested whether this expression was affected by 24 hours of starvation. Consistently, GFP signal was dramatically increased by fasting, especially in body wall muscles. Thus, C. elegans replicates the mammalian tissue-pattern and age-dependent expression of MYTHO.
  Reference: WBPaper00066888
  Transgene: WBTransgene00033903