WormBase Tree Display for Expr_pattern: Expr11951
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| Expr11951 | Expression_of | Gene | WBGene00022598 |
|---|---|---|---|
| Reflects_endogenous_expression_of | WBGene00022598 | ||
| Expression_data (2) | |||
| Subcellular_localization | At a higher resolution, ZTF-8 signal is observed as foci both on chromosomes as well as in the nucleolus. Specifically, 34% of ZTF-8 foci at the premeiotic tip, and 78% at late pachytene, localize to DAPI-stained chromosomes, with the remaining foci being localized to the nucleolus. ZTF-8 localization is also observed in gut and embryonic nuclei. | ||
| ZTF-8 localizes to both chromatin and the nucleolus. ZTF-8 signal is observed in mitotic nuclei at the gonadal distal tip (premeiotic tip). This signal is then reduced upon entrance into meiosis (leptotene/zygotene stages = transition zone) and remains weak through the mid-pachytene stage. However, the ZTF-8 signal increases once again in late pachytene nuclei and persists through late diakinesis oocytes. This dynamic pattern of expression suggests regulation of ZTF-8 during meiotic prophase. | |||
| Type | Antibody | ||
| Picture | WBPicture0000013803 | ||
| Reference | WBPaper00045881 | ||
| Antibody_info | WBAntibody00002560 |
